• Lymphomatoid means lymphoma-like and granulomatosis denotes the microscopic characteristic of the presence of granulomas with polymorphic lymphoid infiltrates and focal necrosis within it. (wikipedia.org)
  • however, there is overwhelming evidence that lymphomatoid granulomatosis is a distinctive type of malignant lymphoma associated with immunosuppression. (medscape.com)
  • Lymphomatoid granulomatosis is considered a distinct form of T cell-rich large B-cell lymphoma. (medscape.com)
  • Lymphomatoid granulomatosis (LYG) is a rare type of angiocentric and angiodestructive lymphoproliferative disorder, which is a type of non-Hodgkin lymphoma. (healthplantip.com)
  • In lymphomas I have conducted studies in rare aggressive primary cutaneous tumors such as gamma/delta T cell lymphoma (expanding the description of the epidermotropic variant) as well as more indolent entities such as lymphomatoid papulosis (type D) and CD4-positive small to medium size T cell lymphoproliferative disorders. (mdanderson.org)
  • The single father of two little boys has a rare lymphoma -- lymphomatoid granulomatosis (LYG). (thebatavian.com)
  • The differential diagnosis of septal perforations associated with WG includes sarcoidosis, cocaine use, SLE, extranodal nasal lymphoma, lymphomatoid granulomatosis (LYG), and excessive use of intranasal corticosteroids. (egms.de)
  • [ 15 ] Simultaneous presentation of multiple myeloma and lymphomatoid granulomatosis in rheumatoid arthritis patients is also reported. (medscape.com)
  • Lymphomatoid granulomatosis (LYG or LG) is a very rare lymphoproliferative disorder first characterized in 1972. (wikipedia.org)
  • Lymphomatoid granulomatosis was first described as a distinct clinicopathologic entity in 1972. (medscape.com)
  • He developed effective therapies for formerly fatal inflammatory and immune-mediated diseases such as polyarteritis nodosa, granulomatosis with polyangiitis (formerly Wegener's granulomatosis), and lymphomatoid granulomatosis. (nih.gov)
  • The aim of our poster is to present several cases of Wegener's granulomatosis (WG) patients with head and neck manifestations including epistaxis, nasal crusting, prolonged sinus infections with atypical microbiological causes and nasal polyposis. (egms.de)
  • Lymphomatoid granulomatosis (LYG) is a rare Epstein-Barr virus -associated systemic angiodestructive lymphoproliferative disease histopathologically defined by angiocentric, angioinvasive and extranodal lesions with polymorphic lymphocyte infiltration. (medscape.com)
  • Lymphomatoid granulomatosis (LYG) involves a B-cell lymphoproliferative process associated with Epstein-Barr virus ( 1 ). (cdc.gov)
  • We describe a 12-year-old boy with Wiskott-Aldrich syndrome who developed a pulmonary vasculitis associated with lymphoreticular proliferation, consistent with the histological and clinical diagnosis of lymphomatoid granulomatosis. (elsevierpure.com)
  • Results from a clinical trial conducted by CCR researchers show that people with low-grade lymphomatoid granulomatosis who are treated with interferon-alpha, a type of immunotherapy, can live for decades after diagnosis. (cancer.gov)
  • An NCI study shows that people with low-grade lymphomatoid granulomatosis who are treated with interferon alfa-2b, a type of immunotherapy, can live for decades after diagnosis. (blueridgecancercare.com)
  • Lymphomatoid granulomatosis (LYG) is an angiocentric destructive proliferation of lymphoid cells predominantly involving the lungs, skin, kidneys, and central nervous system. (survivornet.com)
  • We studied the histological and clinicopathological findings in 42 patients who had lymphomatoid granulomatosis (LYG). (usuhs.edu)
  • Lymphomatoid granulomatosis is a rare disease of unknown prevalence. (medscape.com)
  • Pathobiology and treatment of lymphomatoid granulomatosis, a rare EBV-driven disorder. (medscape.com)
  • Lymphomatoid granulomatosis is a rare precancerous condition triggered by Epstein-Barr virus infection. (cancer.gov)
  • Hospitalized with lymphomatoid granulomatosis, a rare cancer, the father of little two boys has only limited means to deal with his illness. (thebatavian.com)
  • [ 2 , 7 ] A small number of patients with isolated lymphomatoid granulomatosis of the CNS (CNS-LYG) have been reported. (medscape.com)
  • This study will evaluate the response and long-term effects of alpha-interferon in patients with lymphomatoid granulomatosis (LYG). (survivornet.com)
  • To determine the response and long-term efficacy of alpha-Interferon in patients with lymphomatoid granulomatosis (LYG). (survivornet.com)
  • The presence of Epstein-Barr virus (EBV) in the large B cells in lymphomatoid granulomatosis has been confirmed in numerous studies, and large B cells showing the presence of EBV-positive cells by in situ hybridization with the EBER probe is now definitional for lymphomatoid granulomatosis according to the WHO. (medscape.com)
  • This graph shows the total number of publications written about "Lymphomatoid Granulomatosis" by people in this website by year, and whether "Lymphomatoid Granulomatosis" was a major or minor topic of these publications. (rush.edu)
  • Below are the most recent publications written about "Lymphomatoid Granulomatosis" by people in Profiles. (rush.edu)
  • Lymphomatoid granulomatosis usually is progressive and fatal. (medscape.com)
  • Barakat A, Grover K, Peshin R. Rituximab for pulmonary lymphomatoid granulomatosis which developed as a complication of methotrexate and azathioprine therapy for rheumatoid arthritis. (medscape.com)
  • Pulmonary lymphomatoid granulomatosis in a 4-year-old girl: A case report. (nih.gov)
  • 5. Pulmonary lymphomatoid granulomatosis. (nih.gov)
  • 13. Pulmonary lymphomatoid granulomatosis in acquired immunodeficiency syndrome: lesions with Epstein-Barr virus infection. (nih.gov)
  • 19. Expression of cytolytic lymphocyte-associated antigens in pulmonary lymphomatoid granulomatosis. (nih.gov)
  • Gangar P, Venkatarajan S. Granulomatous Lymphoproliferative Disorders: Granulomatous Slack Skin and Lymphomatoid Granulomatosis. (medscape.com)
  • Lymphomatoid granulomatosis (LYG or LG) is a very rare lymphoproliferative disorder first characterized in 1972. (wikipedia.org)
  • Treatment with interferon alfa-2b led to the disappearance of a large lesion (top image) in the lungs of a patient with lymphomatoid granulomatosis, as shown in this computed tomography chest scan. (nih.gov)
  • Results from a clinical trial conducted by researchers at the National Institutes of Health (NIH) show that people with low-grade lymphomatoid granulomatosis who are treated with interferon alfa-2b, a type of immunotherapy, can live for decades after diagnosis . (nih.gov)
  • He and his colleagues treated four people with low-grade lymphomatoid granulomatosis with interferon alfa-2b over a 5-year period, and the treatment eradicated all signs of the disease in three of those patients, known as a complete remission. (nih.gov)
  • That study laid the foundation for the phase 2 trial of interferon alfa-2b in lymphomatoid granulomatosis, which has taken 30 years to complete because of the rarity of the disease and the challenges of recruiting enough patients for the study. (nih.gov)
  • An NCI study shows that people with low-grade lymphomatoid granulomatosis who are treated with interferon alfa-2b, a type of immunotherapy, can live for decades after diagnosis. (feedburner.com)
  • Lymphomatoid Granulomatosis Involving the Lung and Brain in a Child: A Case Report. (nih.gov)
  • A) Bilateral multiple lung nodules and lymphomatoid granulomatosis were diagnosed after lung biopsy. (cdc.gov)
  • 2. Lymphomatoid granulomatosis of the skin and lung. (nih.gov)
  • 17. [Primary and isolated cutaneous lymphomatoid granulomatosis following heart-lung transplantation]. (nih.gov)
  • 1. Cutaneous lymphomatoid granulomatosis: correlation of clinical and biologic features. (nih.gov)
  • 6. EBV-Negative Cutaneous Lymphomatoid Granulomatosis With Concomitant EBV-Positive Pulmonary Involvement: A Potential Diagnostic and Prognostic Pitfall. (nih.gov)
  • 15. Lymphomatoid granulomatosis presenting with cutaneous involvement: a case report and review of the literature. (nih.gov)
  • Primary cutaneous Compact disc30-positive T-cell lymphoproliferative disorders (LPDs), which take into account 30% of cutaneous T-cell lymphomas (CTCLs), express CD30 always, aside from a uncommon subtype called type B lymphomatoid papulosis (LyP) [42]. (spierarchitecturalarts.com)
  • lymphomatoid granulomatosis (LYG)/angiocentric immunoproliferative lesions (AIL) consist of angiocentric and angiodestructive lymphoreticular proliferation predominantly involving the lungs and other extranodal sites, such as the central nervous system (CNS). (lookfordiagnosis.com)
  • Lymphomatoid granulomatosis: a clinical case]. (nih.gov)
  • 4. Lymphomatoid granulomatosis--a single institute experience: pathologic findings and clinical correlations. (nih.gov)
  • A case of lymphomatoid granulomatosis /angiocentric immunoproliferative lesion with long clinical course and diffuse brain involvement. (lookfordiagnosis.com)
  • Although some of these case reports appear promising, larger studies are needed to substantiate the efficacy of rituximab in the treatment of lymphomatoid granulomatosis. (medscape.com)
  • Failure of rituximab monotherapy in lymphomatoid granulomatosis. (medscape.com)
  • Lymphomatoid granulomatosis treated successfully with rituximab in a renal transplant patient. (medscape.com)
  • Cervera P, Guihot A, Gorochov G, Lassoued K, Coppo P. Epstein-Barr virus-driven B Cell Proliferation with CD4(+) T Cell Expansion: A Lymphomatoid Granulomatosis-like Disease Related to Hyperinterleukin-10 Secretion of Remarkably Favourable Outcome with Rituximab. (medscape.com)
  • Successful treatment of mediastinal lymphomatoid granulomatosis with rituximab monotherapy. (medscape.com)
  • Methotrexate-related lymphomatoid granulomatosis in a patient with rheumatoid arthritis]. (nih.gov)
  • Lymphomatoid granulomatosis is a progressive blood vessel disease characterized by a proliferation of abnormal white blood cells (lymphocytes containing the Epstein-Barr virus) that systematically destroy the small arteries in the lungs, skin, and nervous system by forming harmful nodules in the tissues. (callfred.com)
  • Although lymphomatoid granulomatosis is uncommon, the effects of high-grade disease can be debilitating," said Jeffrey Cohen, M.D., chief of the Laboratory of Infectious Diseases at the National Institute of Allergy and Infectious Diseases and a co-leader of the study. (nih.gov)
  • A patient with lymphomatoid granulomatosis and positive EBV serology post-stem cell transplant for multiple myeloma was reported to have complete radiologic remission following 2 weeks of ganciclovir therapy. (medscape.com)
  • Lymphomatoid granulomatosis (LYG) involves a B-cell lymphoproliferative process associated with Epstein-Barr virus ( 1 ). (cdc.gov)
  • Primary orbital lymphomatoid granulomatosis. (medscape.com)
  • Primary cerebral lymphomatoid granulomatosis: report of four cases and literature review. (medscape.com)
  • Association of lymphomatoid granulomatosis with Epstein-Barr viral infection of B lymphocytes and response to interferon-alpha 2b. (medscape.com)
  • Lymphomatoid granulomatosis of the vulva: case report with immunohistochemical analysis. (medscape.com)
  • 8. Immunohistochemical and gene rearrangement studies of central nervous system lymphomatoid granulomatosis. (nih.gov)
  • Lymphomatoid granulomatosis is more common in males than in females and usually presents between ages 30 - 50. (callfred.com)
  • The trial included 67 people with lymphomatoid granulomatosis, 37 with low-grade disease and 30 with high-grade disease. (nih.gov)
  • Grade III lymphomatoid granulomatosis is a disabling condition on the Compassionate Allowance List , which qualifies an individual for an expedited approval process. (callfred.com)
  • Grade III lymphomatoid granulomatosis automatically qualifies you for social security disability benefits under the Social Security Administration's guidelines. (callfred.com)
  • If you or a loved one has been diagnosed with grade III lymphomatoid granulomatosis, contact an experienced social security disability lawyer today. (callfred.com)
  • This study will evaluate the response and long-term effects of alpha-interferon in patients with lymphomatoid granulomatosis (LYG). (nih.gov)