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  • Mice
  • To test this hypothesis in preclinical settings, we have previously developed several experimental models of GVHD using TK+ T-cells in mice. (bioportfolio.com)
  • In 28-day toxicology studies in mice, pharmacological effects were restricted to B lymphoid tissues including B lymphocyte hyperplasia, increased splenic weight without significant increase in spleen size, and increased immunoglobulin production. (bioportfolio.com)
  • Tumor
  • Expression of inducible NO synthase by MSC was induced through synergistic stimulation with tumor necrosis factor α and interferon γ secreted by activated lymphocytes. (frontiersin.org)
  • Syngeneic lymphocytes were transferred from rodents heavily immunized against the tumor to inhibit growth of small established tumors, becoming the first example of ACT. (wikipedia.org)
  • Lymphocytes infiltrating the stroma of growing, transplantable tumors provided a concentrated source of tumor-infiltrating lymphocytes (TIL) and could stimulate regression of established lung and liver tumors. (wikipedia.org)
  • species
  • but the molecular mechanisms by which MSC exert these effects are not entirely understood and the influences of tissue source, species origin, and cell culture conditions have yet to be firmly established. (frontiersin.org)
  • Freemartinism is the normal outcome of mixed-sex twins in all cattle species that have been studied, and it also occurs occasionally in other mammals including sheep, goats and pigs. (wikipedia.org)
  • A freemartin is the normal outcome of mixed twins in all cattle species which have been studied. (wikipedia.org)
  • A variety of tests are used in the detection HHV-6, some of which do not differentiate the two species. (wikipedia.org)
  • Tuberculin
  • Tuberculin skin testing (TST) has been used for years as an aid in diagnosing latent tuberculosis infection (LTBI) and includes measurement of the delayed type hypersensitivity response 48-72 hours after intradermal injection of PPD. (wikipedia.org)
  • commonly
  • Aside from temperature and gas mixture, the most commonly varied factor in culture systems is the cell growth medium. (wikipedia.org)
  • tissue culture
  • The historical development and methods of cell culture are closely interrelated to those of tissue culture and organ culture. (wikipedia.org)
  • In 1885, Wilhelm Roux removed a portion of the medullary plate of an embryonic chicken and maintained it in a warm saline solution for several days, establishing the principle of tissue culture. (wikipedia.org)
  • Ross Granville Harrison, working at Johns Hopkins Medical School and then at Yale University, published results of his experiments from 1907 to 1910, establishing the methodology of tissue culture. (wikipedia.org)
  • Trademark
  • QuantiFERON, also known as QFT, is the registered trademark of the test for tuberculosis infection or latent tuberculosis. (wikipedia.org)
  • Bach
  • By 1975 Bach had improved his technique so that the test would not take days anymore, but hours. (wikipedia.org)
  • days
  • Genetic testing for the Y-chromosome can be performed within days of birth and can aid in the early identification of a sterile female bovine. (wikipedia.org)
  • microbes
  • In addition, if pustules are present, cultures are taken to identify which microbes, if any, may be contributing to the inflammation. (wikipedia.org)
  • drug
  • According to the U.S. Centers for Disease Control, in 2001, the QuantiFERON-TB test (QFT) was approved by the Food and Drug Administration (FDA) as an aid for detecting latent Mycobacterium tuberculosis infection. (wikipedia.org)
  • patients
  • Some of the patients exhibited parallel decreases in both CML and MLR tests, while others showed decreased CML responses but normal MLR responses. (biomedsearch.com)
  • cell type
  • Culture conditions vary widely for each cell type, and variation of conditions for a particular cell type can result in different phenotypes. (wikipedia.org)
  • study
  • The "Thousand Asian American Study" or "TAAS" aims to test 2,000 foreign-born and children of foreign born Asian Americans residing in Sacramento county residents for HBV and (2) counsel a. (bioportfolio.com)
  • potential
  • The 2002 FAO/WHO guidelines recommend that, though bacteria may be generally recognized as safe (GRAS), the safety of the potential probiotic should be assessed by the minimum required tests: Determination of antibiotic resistance patterns Assessment of certain metabolic activities (e.g. (wikipedia.org)
  • One complication of these blood-derived ingredients is the potential for contamination of the culture with viruses or prions, particularly in medical biotechnology applications. (wikipedia.org)
  • symptoms
  • Africans are not even tested for HIV before being treated, but large numbers are given the toxic antiretrovirals, because they have symptoms of disease. (newmediaexplorer.org)
  • Two decision analysis studies suggest that during local outbreaks of influenza, the prevalence will be over 70%, and thus patients with any of these combinations of symptoms may be treated with neuraminidase inhibitors without testing. (wikipedia.org)
  • endothelial cell
  • In the mid-1990s, my research group began to devise a method to establish endothelial cell cultures from human peripheral blood, with an ultimate goal of examining interindividual heterogeneity of endothelial biology. (jci.org)
  • The sphingosine 1-phosphate receptor (S1PR1) is known to act by multiple mechanisms: limiting lymphocyte egress from secondary lymphoid organs, suppressing proinflammatory endothelial cell function, and acting directly on neurons and astrocytes. (pnas.org)
  • chromosome
  • A higher intensity of the test sample colour in a specific region of a chromosome indicates the gain of material of that region in the corresponding source sample, while a higher intensity of the reference sample colour indicates the loss of material in the test sample in that specific region. (wikipedia.org)
  • infection
  • The infection may be confirmed by testing the throat, sputum, or nose for the virus. (wikipedia.org)
  • If undiagnosed or left untreated, HIV usually progresses to AIDS, defined as possessing a CD4+ lymphocyte count under 200 cells/μl or HIV infection plus co-infection with an AIDS-defining opportunistic infection. (wikipedia.org)
  • The analysis includes testing for the presence of proteins, glucose, ketones, haemoglobin, bilirubin, urobilinogen, acetone, nitrite and leucocytes as well as testing of pH and specific gravity or to test for infection by different pathogens. (wikipedia.org)
  • QuantiFERON, also known as QFT, is the registered trademark of the test for tuberculosis infection or latent tuberculosis. (wikipedia.org)
  • An individual is considered positive for M. tuberculosis infection if the IFN-gamma response to TB antigens is above the test cut-off (after subtracting the background IFN-gamma response in the negative control). (wikipedia.org)
  • According to the U.S. Centers for Disease Control, in 2001, the QuantiFERON-TB test (QFT) was approved by the Food and Drug Administration (FDA) as an aid for detecting latent Mycobacterium tuberculosis infection. (wikipedia.org)
  • Tuberculin skin testing (TST) has been used for years as an aid in diagnosing latent tuberculosis infection (LTBI) and includes measurement of the delayed type hypersensitivity response 48-72 hours after intradermal injection of PPD. (wikipedia.org)
  • persistent
  • In 2002, lymphodepletion using a nonmyeloablative chemotherapy regimen administered immediately before TIL transfer increased cancer regression, as well as the persistent oligoclonal repopulation of the host with the transferred lymphocytes. (wikipedia.org)
  • methodology
  • Ross Granville Harrison, working at Johns Hopkins Medical School and then at Yale University, published results of his experiments from 1907 to 1910, establishing the methodology of tissue culture. (wikipedia.org)
  • positive
  • But what about all the people that test HIV positive? (newmediaexplorer.org)
  • Apparently, they test positive to something else than the virus. (newmediaexplorer.org)
  • There are strips which serve different purposes, such as qualitative strips that only determine if the sample is positive or negative, or there are semi-quantitative ones that in addition to providing a positive or negative reaction also provide an estimation of a quantitative result, in the latter the colour reactions are approximately proportional to the concentration of the substance being tested for in the sample. (wikipedia.org)
  • reported evidence suggesting false positive TST results are common and that QFT testing could guide more targeted treatment and alleviate unnecessary anti-tuberculous treatment. (wikipedia.org)
  • cells
  • Evaluation of human being malignancy cell lines is definitely generally performed using cells cultured on strict plastic material, or in Matrigel or smooth agar, the mechanised properties of which are badly described and/or hard to modulate. (techtasys.com)
  • In this research we possess modified a technique for culturing cells on biologically relevant smooth substrates using ECM-conjugated polyacrylamide (Pennsylvania) gel that can period the tightness range of 100 PaC150,000 Pennsylvania. (techtasys.com)
  • Cells can be isolated from tissues for ex vivo culture in several ways. (wikipedia.org)
  • however, only the white cells are capable of growth in culture. (wikipedia.org)
  • Alternatively, pieces of tissue can be placed in growth media, and the cells that grow out are available for culture. (wikipedia.org)
  • Cells that are cultured directly from a subject are known as primary cells. (wikipedia.org)
  • All T cells begin as CD4-CD8-TCR- cells at the DN (double-negative) stage, where an individual cell will rearrange its T cell receptor genes to form a unique, functional molecule, which they, in turn, test against cells in the thymic cortex for a minimal level of interaction with self-MHC. (wikipedia.org)
  • In 2016, CD19-specific chimeric antigen receptor (CAR)-modified T cells were used to treat patients with relapsed and refractory CD19+ B cell malignancies, including B cell acute lymphoblastic leukemia (B-ALL) harboring rearrangement of the mixed lineage leukemia (MLL) gene with CD19 CAR-T cells. (wikipedia.org)
  • Comparative genomic hybridization is a molecular cytogenetic method for analysing copy number variations (CNVs) relative to ploidy level in the DNA of a test sample compared to a reference sample, without the need for culturing cells. (wikipedia.org)
  • The authors painted a series of individual human chromosomes from a DNA library with two different fluorophores in different proportions to test the technique, and also applied CGH to genomic DNA from patients affected with either Downs syndrome or T-cell prolymphocytic leukemia as well as cells of a renal papillary carcinoma cell line. (wikipedia.org)
  • widely
  • Culture conditions vary widely for each cell type, and variation of conditions for a particular cell type can result in different phenotypes. (wikipedia.org)
  • blood
  • Blood tests are also performed to assess function of major organs and to assess safety for chemotherapy. (wikipedia.org)
  • One complication of these blood-derived ingredients is the potential for contamination of the culture with viruses or prions, particularly in medical biotechnology applications. (wikipedia.org)
  • whole
  • The cell lines examined diverged into two groups centered on their expansion information: solidity reliant lines generally exhibited raising cell development as extracellular solidity improved, while rigidity indie lines grew well across the whole tested range of matrix rigidity equally. (techtasys.com)
  • method
  • The test method consists of immersing the test strip completely in a well mixed sample of urine for a short period of time, then extracting it from the container and supporting the edge of the strip over the mouth of the container to remove excess urine. (wikipedia.org)
  • This method is known as explant culture. (wikipedia.org)
  • plastic
  • The test strips consist of a ribbon made of plastic or paper of about 5 millimetre wide, plastic strips have pads impregnated with chemicals that react with the compounds present in urine producing a characteristic colour. (wikipedia.org)
  • human
  • Your material is recognized a Tested or human law. (southwayinc.com)
  • CGH does, however, allow for the exploration of all 46 human chromosomes in single test and the discovery of deletions and duplications, even on the microscopic scale which may lead to the identification of candidate genes to be further explored by other cytological techniques. (wikipedia.org)
  • research
  • Research in rats has indicated that THC prevented hydroperoxide-induced oxidative damage as well as or better than other antioxidants in a chemical (Fenton reaction) system and neuronal cultures. (wikipedia.org)
  • In 1891, Robert Koch invited Ehrlich to join the staff at his Berlin Institute of Infectious Diseases, where in 1896 a new branch, the Institute for Serum Research and Testing (Institut für Serumforschung und Serumprüfung), was established for Ehrlich's specialization. (wikipedia.org)
  • different
  • A standard urine test strip may comprise up to 10 different chemical pads or reagents which react (change color) when immersed in, and then removed from, a urine sample. (wikipedia.org)
  • often
  • The test can often be read in as little as 60 to 120 seconds after dipping, although certain tests require longer. (wikipedia.org)
  • types
  • There are two major types of Hodgkin lymphoma: classical Hodgkin lymphoma and nodular lymphocyte-predominant Hodgkin lymphoma. (wikipedia.org)
  • taken
  • The time taken for the appearance of the test results on the strip can vary from a few minutes after the test to 30 minutes after immersion of the strip in the urine (depending on the brand of product being used). (wikipedia.org)
  • results
  • Automated readers of test strips also provide results using units from the International System of Units. (wikipedia.org)