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  • pulmonary
  • On post operative day 1 (24 hours following lung transplant), the investigators will evaluate whether extravascular lung water measured at 24 hours correlates with pulmonary edema determined by reviewers of the CXR blinded to the extravascular lung water measurement. (clinicaltrials.gov)
  • 24 hours following lung transplant, the investigators will evaluate whether the combination of extravascular lung water and pulmonary permeability measurements at 24 hours correlate with the presence and severity of primary graft dysfunction (PGD) at 24 hours. (clinicaltrials.gov)
  • The median extravascular lung water and pulmonary permeability measurements will be calculated. (clinicaltrials.gov)
  • The combinations of above/below median extravascular lung water with above/below median pulmonary permeability will be correlated to the presence of PGD. (clinicaltrials.gov)
  • The investigators will compare whether immediate (time 0) post operative measurements of the combination of extravascular lung water and pulmonary permeability can predict the later onset (24 hours) of primary graft dysfunction. (clinicaltrials.gov)
  • injury
  • Mitogen-activated protein kinases have been implicated in ventilator-induced lung injury though their functional significance remains incomplete. (plos.org)
  • We characterize the role of p38 mitogen-activated protein kinase/mitogen activated protein kinase kinase-3 and c-Jun-NH 2 -terminal kinase-1 in ventilator-induced lung injury and investigate novel independent mechanisms contributing to lung injury during mechanical ventilation. (plos.org)
  • C57/BL6 wild-type mice and mice genetically deleted for mitogen-activated protein kinase kinase-3 ( mkk-3 −/− ) or c-Jun-NH 2 -terminal kinase-1 ( jnk1 −/− ) were ventilated, and lung injury parameters were assessed. (plos.org)
  • We demonstrate that mkk3 −/− or jnk1 −/− mice displayed significantly reduced inflammatory lung injury and apoptosis relative to wild-type mice. (plos.org)
  • Since jnk1 −/− mice were highly resistant to ventilator-induced lung injury, we performed comprehensive gene expression profiling of ventilated wild-type or jnk1 −/− mice to identify novel candidate genes which may play critical roles in the pathogenesis of ventilator-induced lung injury. (plos.org)
  • We demonstrate that mitogen-activated protein kinase pathways mediate inflammatory lung injury during ventilator-induced lung injury. (plos.org)
  • Ventilator-associated lung injury arises as a clinical complication of mechanical ventilation. (plos.org)
  • Animal models have been used extensively to model ventilator-induced lung injury (VILI) yet the underlying mechanisms remain incompletely understood. (plos.org)
  • MAPK activation is associated with various forms of inflammatory lung injury. (plos.org)
  • mucus
  • A clinical study into high-frequency chest wall oscillation vests - assessing their short-term impact on standard measures of lung function before and during use - challenges the view that these devices work through airflow bias in the lungs, the process responsible for mucus movement when breathing. (cysticfibrosisnewstoday.com)
  • Examination of the coughed up mucus is important in any lung infection and often reveals mixed bacterial flora. (wikipedia.org)
  • pneumonia
  • Other contributory factors which are likely to lead to acute lung injury comprise pneumonia, sepsis, major trauma, and inhalation of noxious fumes. (tmrresearch.com)
  • Medical terms related to the lung often begin with pulmo-, from the Latin pulmonarius (of the lungs) as in pulmonology, or with pneumo- (from Greek πνεύμων "lung") as in pneumonia. (wikipedia.org)
  • 2017
  • Jonathan "Jon" Lung is an American television personality, product designer and graphic designer, known as a co-host on the Science Channel TV series MythBusters, which premieres November 15, 2017, and is a revival of the 2003 - 2016 incarnation of the program. (wikipedia.org)
  • Lung and his co-host Brian Louden won their hosting duties on the reality television competition series MythBusters: The Search, which aired in January and February 2017. (wikipedia.org)
  • Lung relocated to Los Angeles when he took the job of hosting MythBusters in 2017. (wikipedia.org)
  • disease
  • Asthma is a lung disease that makes breathing difficult for millions of Americans. (lung.org)
  • Make a difference by delivering research, education and advocacy to those impacted by lung disease. (lung.org)
  • Peak flow measurements will indicate a lung condition however a spirometric test on lung capacity and patients ability to move air in and out of the lungs plus in more advanced cases an X-ray test or CT scan is available to confirm whether someone has the disease or not. (wikipedia.org)
  • Obstructive lung disease is a category of respiratory disease characterized by airway obstruction. (wikipedia.org)
  • Although COPD shares similar characteristics with all other obstructive lung diseases, such as the signs of coughing and wheezing, they are distinct conditions in terms of disease onset, frequency of symptoms and reversibility of airway obstruction. (wikipedia.org)
  • Silo-filler's disease (not to be confused with farmer's lung associated with inhalation of biologic dusts) results from inhalation of nitrogen dioxide (NO2) gas from fresh silage. (wikipedia.org)
  • The British Lung Foundation is a British charity that promotes lung health and supports those affected by lung disease. (wikipedia.org)
  • It has maintained strong links with the medical profession, as well as utilising the talents of people from all walks of life who share a determination to try to conquer lung disease in the 21st Century. (wikipedia.org)
  • The BLF also campaigns to raise public awareness of lung disease and the impact it has on so many lives through poster campaigns, events and by maintaining a media profile. (wikipedia.org)
  • Indium lung is a rare occupational lung disease caused by exposure to respirable indium in the form of indium tin oxide. (wikipedia.org)
  • There is no standardized treatment for indium lung disease. (wikipedia.org)
  • Indium lung disease has been fatal in several cases. (wikipedia.org)
  • Metsovo lung was an epidemic of lung disease resulting from domestic exposure to asbestos in the village of Metsovo in northwest Greece. (wikipedia.org)
  • Indium
  • Hemoptysis has also been seen in people with indium lung. (wikipedia.org)
  • Emphysema has been associated with indium lung, but may not be part of the syndrome. (wikipedia.org)
  • Indium lung is caused by exposure to indium tin oxide in a variety of occupational contexts, including reclamation and production. (wikipedia.org)
  • CT scanning and radiography can be used to aid in the diagnosis of indium lung. (wikipedia.org)
  • Multiple abnormal laboratory findings have been noted in indium lung. (wikipedia.org)
  • High levels of serum indium have been found in all cases of indium lung. (wikipedia.org)
  • The National Institute of Occupational Safety and Health, Japan (JNIOSH) set limits for acceptable exposure at 0.0003 mg/m3 after the discovery of indium lung. (wikipedia.org)
  • bronchi
  • Many obstructive diseases of the lung result from narrowing (obstruction) of the smaller bronchi and larger bronchioles, often because of excessive contraction of the smooth muscle itself. (wikipedia.org)
  • SCLC
  • On relatively rare occasions, malignant lung tumors are found to contain components of both SCLC and NSCLC. (wikipedia.org)
  • malignant
  • Large cell lung carcinoma (LCLC) is a heterogeneous group of undifferentiated malignant neoplasms originating from transformed epithelial cells in the lung. (wikipedia.org)
  • transplants
  • Lung transplants aren't carried out frequently in the UK. (www.nhs.uk)
  • In England, during 2013-14, 198 lung transplants were carried out. (www.nhs.uk)
  • The demand for lung transplants is far greater than the available supply of donated lungs. (www.nhs.uk)
  • However, lung transplants from living donors are currently rare in the UK. (www.nhs.uk)
  • Most people who receive lung transplants from living donors have cystic fibrosis and are close relatives of the donors. (www.nhs.uk)
  • lung transplants are more likely to be successful. (wikipedia.org)
  • airflow
  • None of the vest groups showed statistically significant increased airflow in the lungs. (cysticfibrosisnewstoday.com)
  • It has been claimed that one of the operating principles of HFCWO vests is creating 'airflow bias' in the lungs, but valid clinical evidence supporting that claim is lacking," he added. (cysticfibrosisnewstoday.com)
  • Based on the concept of increased cephalad airflow bias in the lungs during use of HFCWO devices, one might expect that the expiratory peak flow [PEF] should be increased," the study noted. (cysticfibrosisnewstoday.com)
  • Spirometry, a measurement of lung function, can provide an assessment of the severity, reversibility, and variability of airflow limitation, and help confirm the diagnosis of asthma. (wikipedia.org)
  • The lungs also provide airflow that makes vocal sounds including human speech possible. (wikipedia.org)
  • clinical
  • The FP-1201-lyo treatment for acute lung injury is now in the 3rd phase of clinical trials and is anticipated to obtain European marketing authorization in the near future. (tmrresearch.com)
  • The increased total lung capacity (hyperinflation) can result in the clinical feature of a "barrel chest" - a chest with a large front-to-back diameter that occurs in some individuals with COPD. (wikipedia.org)
  • COPD
  • The residual volume, the volume of air left in the lungs following full expiration, is often increased in COPD, as is the total lung capacity, while the vital capacity remains relatively normal. (wikipedia.org)
  • A chest x-ray is often ordered to look for hyperinflation and rule out other lung conditions but the lung damage of COPD is not always visible on a chest x-ray. (wikipedia.org)
  • citation needed] The British Lung Foundation's COPD Project is a three-year project which was set up in January 2007. (wikipedia.org)
  • Support the delivery of COPD campaigns and publications, developed and produced by the British Lung Foundation. (wikipedia.org)
  • 2016
  • Lung attended the School of Visual Arts (SVA) in Manhattan, where he received his MFA in Products of Design in 2016. (wikipedia.org)
  • Lung appeared on the reality television competition program MythBusters: The Search, which premiered on The Science Channel in January 2016. (wikipedia.org)
  • 2002
  • A goofy prank played live and on the air during a Minneapolis news broadcast in 2002, featuring Lung Leg, Mike Etoll and others. (wikipedia.org)
  • bronchiectasis
  • Although rare in modern times, can include spread of infection to other lung segments, bronchiectasis , empyema , and bacteremia with metastatic infection such as brain abscess . (wikipedia.org)
  • diagnosis
  • Recovery varies from patient to patient depending on what stage the condition was at when the patient consulted the doctor, the speed of diagnosis and application of the appropriate treatment to prevent residual damage to the lungs and many make a full recovery. (wikipedia.org)
  • On average, the British Lung Foundation invests one million pounds a year in research projects - all aiming to improve the diagnosis or treatment of lung conditions. (wikipedia.org)
  • fluid
  • The pleural cavity normally contains a small amount of fluid that helps the lungs move smoothly in the chest when you breathe. (cancer.gov)
  • Ongoing research in the area of fluid conservation and lung-protective ventilation strategies have demonstrated improvements in survival rate of patients. (tmrresearch.com)
  • thoracentesis (samples fluid that has built up around the lungs). (familydoctor.org)
  • When the lungs are formed the fetus is held in the fluid-filled amniotic sac and so they do not function to breathe. (wikipedia.org)
  • pleural
  • Each lung is enclosed within a pleural sac which allows the inner and outer walls to slide over each other whilst breathing takes place, without much friction. (wikipedia.org)
  • asbestos
  • Inflammation from toxic substances, such as tobacco smoke, asbestos, and environmental dusts, can also produce significant damage to the lung. (britannica.com)
  • Samples of the whitewash were sent to Mount Sinai Hospital, and proved to contain fibers of tremolite asbestos identical to the material previously obtained from the lungs of Metsovites. (wikipedia.org)
  • left
  • Tumour is on the left, obstructing the bronchus (lung). (wikipedia.org)
  • The left lung shares space with the heart, and has an indentation in its border called the cardiac notch of the left lung to accommodate this. (wikipedia.org)
  • After her film career in the 1980s, Lung Leg left the public sphere for several years. (wikipedia.org)
  • At Alternative Press, Scott Heisel felt that "now we're left with Collapsible Lung, the dreadfully plastic yang to Forget's emotional, powerful yin. (wikipedia.org)
  • Lung left his restaurant job, and went on to play numerous other villains in the following decade. (wikipedia.org)
  • carcinoma
  • Pie chart showing incidences of non-small cell lung cancers as compared to small cell carcinoma shown at right, with fractions of smokers versus non-smokers shown for each type. (wikipedia.org)
  • primary squamous carcinoma of the lung is the most common. (wikipedia.org)
  • diseases
  • Following is an overview of the main obstructive lung diseases. (wikipedia.org)
  • Infectious lung diseases can also be acquired in an occupational context. (wikipedia.org)
  • World Trade Center lung is a cluster of diseases caused by exposure to fallout at Ground Zero of the September 11 attacks in 2001. (wikipedia.org)
  • treatments
  • Faron Pharmaceuticals, Ltd. is at present engaged in the development of pharmacological treatments for acute lung injury with the help of a consortium consisting European Commission, Traumakine program (University College London Hospital (UCLH) and University of Torino and University of Turku). (tmrresearch.com)