• The triterpenoid fraction (100 and 200 mg/kg) of the fruit bodies of Ganoderma lucidum inhibited primary solid-tumor growth in the spleen, liver metastasis and secondary metastatic tumor growth in the liver in intrasplenic Lewis lung carcinoma (LLC)-implanted mice. (nih.gov)
  • We found that MMDX cytotoxicity for cultured M5076 tumor cells was potentiated 22-fold by preincubating the drug with NADPH-supplemented liver microsomes from untreated C57BL/6 female mice. (unboundmedicine.com)
  • Administration of FGF2 neutralizing antibody to mice bearing experimental liver metastases phenocopied neutrophil depletion by reducing liver metastatic colony growth, vascular density, and branching. (ox.ac.uk)
  • Mice homozygous for a different knock-out allele exhibit increased susceptibility to experimental autoimmune encephalomyelitis with increased Th17 response. (jax.org)
  • The National Institutes of Health July, 1995, Toxicology Study, stated "There was some evidence of carcinogenic activity of methylphenidate hydrochloride (Ritalin) in male and female B6C3F1 mice based on the occurrence of hepatocellular neoplasms (liver cancer). (hull.ee)
  • Pre-operative hepatic artery chemoembolization followed by orthotopic liver transplantation for HCC. (aetna.com)
  • Pre-operative use as a bridge to orthotopic liver transplantation for HCC. (aetna.com)
  • We seek to provide comprehensive data, analyses, and evidence-based research including tumorigenesis and metastasis, immunology and immunotherapy, stem cell transplantation, radiotherapy and oncological drug therapy, artificial intelligence and big data in neoplasms, and much more. (openaccesspub.org)
  • TIPS is progressively utilized in the administration of BCS and decreases the requirement for liver transplantation. (imedpub.com)
  • Hepatocellular carcinoma (HCC) typically arises in fibrotic or cirrhotic livers, which are characterized by pathogenic angiogenesis. (cancerindex.org)
  • Over the last 10 years, Dr. Choi has been involved in the development and application of the non-invasive methods for liver fat and iron quatitaion and evaluation of the underlying liver fibrosis and hepatocellular carcinoma. (mdanderson.org)
  • Although Hürthle cell carcinoma was previously considered a variant of follicular cell neoplasms, which are generally less aggressive, the 2017 World Health Organization (WHO) classification of endocrine tumors reclassified it as a distinct entity. (medscape.com)
  • In contrast, anaplastic carcinoma is quite aggressive and has a poor prognosis, while patients with metastatic medullary carcinoma may live for many years but generally succumb to their cancer. (msdmanuals.com)
  • Experimentally induced tumors of the LIVER . (online-medical-dictionary.org)
  • For treatment of neuroendocrine cancers (i.e., carcinoid tumors and pancreatic endocrine tumors) involving the liver. (aetna.com)
  • Tumors or cancer of the LIVER. (lookformedical.com)
  • Reimbursement for radiofrequency ablation of tumors continues to broaden, with local Medicare agencies and most major insurers covering the procedure for unresectable liver neoplasms. (diagnosticimaging.com)
  • RFA is covered for certain types of liver and kidney tumors and, subject to certain clinical criteria, for chronic spinal pain. (diagnosticimaging.com)
  • They point to the wide acceptance of RFA for liver and bone tumors as a first step toward even greater coverage. (diagnosticimaging.com)
  • M5076 tumors or experimental M5076 liver metastases. (unboundmedicine.com)
  • Neoplasms is morphologically identical to tumors steroid use will cause a deepening of the people using steroids can get liver cancer, have organ damage, psychological defects, hormonal changes, and sometimes infertility. (nattererbcn.com)
  • Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. (lookformedical.com)
  • However, DC-SIGNR as a family member of selectin participates in gastric cancer liver metastasis remains unknown. (biomedcentral.com)
  • Investigation the biological effects of DC-SIGNR were verified by MTT, wounding and transwell in vitro and experiments on animals to confirm gastric cancer liver metastasis by IVIS. (biomedcentral.com)
  • DC-SIGNR knockdown inhibited the proliferation, migration and invasion of gastric cancer cells in vitro and suppressed the liver metastasis in vivo. (biomedcentral.com)
  • DC-SIGNR promoted gastric cancer liver metastasis mediated with HNRNPKP2 which expression was regulated by STAT5A. (biomedcentral.com)
  • These findings indicated potential therapeutic candidates for gastric cancer liver metastasis. (biomedcentral.com)
  • Despite surgical resection and chemoradiotherapy can control most cancer cells [ 5 ], a surgical resection has been rarely indicated for liver metastasis from gastric cancer [ 6 ]. (biomedcentral.com)
  • So far, the complex molecular mechanism of liver metastasis has still remained essentially unknown. (biomedcentral.com)
  • In experimental metastasis studies, researchers demonstrate that liver sinusoidal endothelial cell lectin (LSECtin) mediated colon cancer cells metastasis to liver displays enhanced abilities to the specific organ [ 8 ]. (biomedcentral.com)
  • Moreover, using an E-selectin-specific monoclonal antibody reduces liver metastasis, showing that E-selectin is involved in metastatic formation in this organ [ 11 ]. (biomedcentral.com)
  • Journal of Neoplasms focuses on both experimental and clinical studies related to neoplasms, such as cancer and tumor biology, carcinogenesis, and metastasis. (openaccesspub.org)
  • Aetna considers intra-hepatic chemotherapy (infusion) medically necessary for members with liver metastases from colorectal cancer. (aetna.com)
  • Intra-hepatic chemotherapy for other indications not listed above, including treatment of liver primaries or metastases from other primaries (e.g., breast) besides colorectal cancer. (aetna.com)
  • Intra-hepatic microspheres for metastases from esophageal cancer, gallbladder cancer, uveal melanom a, liver metastases of pancreatic adenocarcinoma, and other indications not listed above. (aetna.com)
  • Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules. (lookformedical.com)
  • Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. (lookformedical.com)
  • A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. (lookformedical.com)
  • Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C. (lookformedical.com)
  • Here, neutrophils promoted the growth of hepatic metastases, given that depletion of neutrophils in already established, experimental, murine liver metastases led to diminished metastatic growth. (ox.ac.uk)
  • Similarly, hepatic sinusoidal endothelial E-selectin expression is up regulated by highly metastatic cells entering the liver [ 10 ]. (biomedcentral.com)
  • Drug-eluting beads trans-arterial chemoembolization for leiomyosarcoma, liver metastases from colorectal cancer, and for primary and liver-dominant metastatic disease of the liver. (aetna.com)
  • In addition, the procedure is covered for curative efforts aimed at primary or metastatic malignant neoplasms when the patient is unable to tolerate surgical resection. (diagnosticimaging.com)
  • Metastatic spreading and the formation of secondary neoplasms from primary site are not random, exhibiting organ selectivity [ 7 ]. (biomedcentral.com)
  • The MDS Foundation, Inc. (MDSF) is an international organization devoted to the support and education of patients and healthcare providers with innovative research in the fields of MDS and related myeloid neoplasms in order to accelerate progress leading to the control and cure of these diseases. (prweb.com)
  • This Special Issue will include papers investigating the pathological mechanisms of T2DM and liver diseases such as NASH, and diagnostics using new biomarkers. (mdpi.com)
  • It also covers advances in immunotherapy, genetics, and genomics of neoplasms, novel biomarkers, and advances in imaging in neoplasm diagnosis and prognosis. (openaccesspub.org)
  • Chemoembolization (CE) for other indications including palliative treatment of liver metastases from other non-neuroendocrine primaries (e.g., breast cancer, cervical cancer, colon cancer, esophageal cancer, melanoma, rhabdomyosarcoma, or unknown primaries) and CE of the pancreas for pancreatic cancer. (aetna.com)
  • Electro-coagulation for the treatment of liver metastases. (aetna.com)
  • One-shot" arterial chemotherapy for members with liver metastases from colorectal cancer. (aetna.com)
  • Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)
  • a complete loss of MMDX activity was observed in liver metastases-bearing animals receiving 40 microg/kg MMDX i.v. plus TAO. (unboundmedicine.com)
  • We found that human colorectal cancer liver metastases and murine gastrointestinal experimental liver metastases are infiltrated by neutrophils. (ox.ac.uk)
  • CONCLUSION: Here, we show, using FGF2 as an example, that identification of factors responsible for the protumoral effects of infiltrating myeloid cells can be used to target established liver metastases. (ox.ac.uk)
  • By day 7, metastases had appeared in the distal femur, in the glomeruli of the kidney, and diffusely throughout the liver and lungs. (mcmaster.ca)
  • Neoplasms are abnormal, uncontrolled growths of tissue that have the potential to spread and cause serious health issues. (openaccesspub.org)
  • JN is pleased to publish research that covers topics related to neoplasms, ranging from epidemiology to pathology, carcinogenesis, etiopathogenesis, and clinical management. (openaccesspub.org)
  • Experimental and Molecular Pathology 2001;70(3):333-343. (cdc.gov)
  • A benign epithelial tumor of the LIVER . (nih.gov)
  • A benign neoplasm cannot be distinguished from a malignant neoplasm on the basis of cytologic analysis of a fine-needle aspiration (FNA) biopsy specimen. (medscape.com)
  • A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, and chemicals from the environment. (lookformedical.com)
  • Liver diseases associated with ALCOHOLISM. (lookformedical.com)
  • The poisonous compounds are alkaloids which cause cattle diseases, neoplasms, and liver damage and are used to produce cancers in experimental animals. (bvsalud.org)
  • Likewise, there is limited but increasing epidemiologic and experimental studies linking autoimmune diseases and occupational exposure to agents such as silica, solvents, pesticides and UVR. (cdc.gov)
  • Neoplasms are one of the most complex diseases due to their indefinite range of severity and type, which makes research and medical advancements a challenging and ongoing process. (openaccesspub.org)
  • Increased incidences of non-viral, non-alcohol liver hepatitis, that ultimately progress to cirrhosis, occur in certain workers, such as painters and printers, presumably due to solvent exposure. (cdc.gov)
  • In addition, the blood stream model can give early admonition boundaries of the comparing gateway vein trunk and entrance vein microtubules for apoplexy and liver cirrhosis. (imedpub.com)
  • This model presents the total course of blood stream from sinusoids to the gateway vein, adjusts to the conclusion of entrance hypertension of apoplexy and liver cirrhosis, and gives another strategy to harmless entry vein pressure discovery according to the viewpoint of biomechanics. (imedpub.com)
  • N-Ethylmaleimide treatment of rat liver plasma membranes results in an adenylyl cyclase (EC 4.6.1.1) system that shows no measurable cyclizing activity but retains both an active glucagon receptor and a receptor-sensitive regulatory component N as assessed by reconstitution into cyclase-negative (cyc-) membranes from S49 murine lymphoma. (nih.gov)
  • Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS. (lookformedical.com)
  • Even without dietary intake, theobromine may occur in the body as it is a product of the human metabolism of caffeine which is metabolised in the liver into 10% theobromine, 4% theophylline, and 80% paraxanthine. (selfdecode.com)
  • Here, we demonstrate that ST18 is critical for tumor progression and maintenance in a mouse model of liver cancer, based on oncogenic transformation and adoptive transfer of primary precursor cells (hepatoblasts). (unimi.it)
  • Your gift will help support our mission to end cancer and make a difference in the lives of our patients. (mdanderson.org)
  • Her clinical experience is focused on male and female pelvic MRI, including the prostate, uterus, cervix and rectum, liver imaging, functional MRI including dynamic contrast enhanced (DCE) - MRI, DWI and spectroscopy (MRS). She has extensive clinical experience on prostate MRI parallels with building up a highly successful prostate imaging program at MD Anderson Cancer Center. (mdanderson.org)
  • This trial is studying how well SPECT/CT with technetium Tc-99m sulfur colloid works in measuring liver function in patients with liver cancer. (withpower.com)
  • The presence of dense adhesions, advanced liver disease, unexpected cancer, or a severely inflamed gallbladder or encountering troublesome bleeding should prompt assessment of the need to convert to an open procedure. (medscape.com)
  • Iodized oil enhances the thermal effect of high-intensity focused ultrasound on ablating experimental liver cancer. (edu.ni)
  • Inflammatory responses resulting from workplace exposures are usually observed in specific target organs, such as the lung, skin and liver and, if persistent, may progress to fibrosis, granulomatous disease or even cancer. (cdc.gov)
  • Co-occurring Fatigue and Lymphatic Pain Incrementally Aggravate Their Negative Effects on Activities of Daily Living, Emotional Distress, and Overall Health of Breast Cancer Patients. (duke.edu)
  • Journal of Neoplasms (JN) is a peer-reviewed, open access journal that publishes high-quality, scholarly articles in the fields of neoplasms and oncology, with a focus on the biology, development, and treatment of cancer. (openaccesspub.org)
  • ST18 expression in liver cells was induced by inflammatory cues, including acute or chronic inflammation in vivo, as well as coculture with macrophages in vitro. (unimi.it)
  • 8) Concomitant chronic disease such as chronic renal failure (CKD), nephrotic syndrome, acute or chronic liver disease, chronic obstructive pulmonary disease (COPD), decompensated ischemic heart disease, hypertensive encephalopathy, cerebrovascular disease (CVA), diabetes mellitus with metabolic decompensation, arterial insufficiency acute peripheral and complications in other organs such as kidney (Kinmestiel - Wilson, Necrotizing papillitis). (who.int)
  • These ideas motivated a comparison between results of molecular genetic studies of experimental evolution in yeast and the molecular genetic phenomena associated with tumorigenesis and tumor progression. (nih.gov)
  • A primary malignant neoplasm of epithelial liver cells. (lookformedical.com)
  • It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
  • Conclusion: ST18 expression in epithelial cells is induced by tumor-associated macrophages, contributing to the reciprocal feed-forward loop between both cell types in liver tumorigenesis. (unimi.it)
  • Our research interest is focused on the vascular biology of the liver. (tum.de)
  • Vascular and histopathological classification of rodent models for liver tumorigenesis to improve the reproducibility of histopathological results in biomedical research. (tum.de)
  • Tat peptides increased nuclear localization of [(111)In]-mIgG after iv injection in tumor, kidney and liver cells, but only in tumor cells after intratumoral injection. (ox.ac.uk)
  • Closed vesicles of fragmented endoplasmic reticulum created when liver cells or tissue are disrupted by homogenization. (lookformedical.com)
  • A greater (50-fold) potentiation of MMDX cytotoxicity was observed after its preincubation with liver microsomes isolated from animals pretreated with the prototypical CYP3A inducer pregnenolone-16alpha-carbonitrile. (unboundmedicine.com)
  • In contrast, in vivo administration of the selective CYP3A inhibitor troleandomycin (TAO) reduced both potentiation of MMDX cytotoxicity and the rate of CYP3A-catalyzed N-demethylation of erythromycin by isolated liver microsomes (55.5 and 49% reduction, respectively). (unboundmedicine.com)
  • Transarterially administered gene therapy for primary and secondary liver malignancies. (aetna.com)
  • Furthermore, experimental in vitro and in vivo studies and clinical studies examining potential new approaches to attenuate DLD are welcome. (mdpi.com)
  • Ultrastructural observation of liver tissue ablation induced by high-intensity focused ultrasound. (edu.ni)
  • Nonalcoholic fatty liver disease (NAFLD) which is the most prevalent chronic liver disease, is associated with type 2 diabetes (T2D). (mdpi.com)
  • Nonalcoholic fatty liver disease (NAFLD) is a globally observed metabolic disease with high prevalence both in adults and children. (mdpi.com)
  • Treatment for neoplasms can include surgery, chemotherapy, radiation therapy, and sometimes a combination of therapies. (openaccesspub.org)
  • Liver-related mortality is the 3rd leading cause in T2D patients. (mdpi.com)
  • Thyroid status in children and adolescents living in areas contaminated with radioactive materials after the Chernobyl accidents. (cdc.gov)
  • Clinical and experimental medicine 2023 0 0. (cdc.gov)
  • This Clinical Policy Bulletin addresses treatment approaches for liver and other neoplasms. (aetna.com)
  • a soluble thermostable fraction of mammalian liver is used in the treatment of pernicious anemia. (lookformedical.com)
  • But Cigna considers the procedure experimental, said spokesperson Amy Turkington, and therefore does not cover it for other treatment uses. (diagnosticimaging.com)
  • Even despite the treatment of severe alopecia are lighter to the liver. (nattererbcn.com)
  • Over 50 years ago, niacinamide pioneer William Kaufman, M.D., Ph.D, observed: "Some patients have a response to niacinamide therapy which seems to be the clinical equivalent of 'decreased running' observed in experimental animals. (hull.ee)
  • Neoplasms containing cyst-like formations or producing mucin or serum. (lookformedical.com)