- Decreased concentrations of antioxidant support the hypothesis that alcoholic hepatitis is an important causative factor in pathogenesis of lipid peroxidation. (sumathipublications.com)
- Effects of growth hormone and insulin-like growth factor-I on the iron-induced lipid peroxidation in the rat liver and porcine thyroid homogenates. (nel.edu)
- Growth hormone (GH) and its tissue mediator, insulin-like growth factor-I (IGF-I), are involved in oxidative processes, lipid peroxidation (LPO) included. (nel.edu)
- [9] Research into how vitamin E prevents the process of lipid peroxidation led to the identification of antioxidants as reducing agents that prevent oxidative reactions, often by scavenging reactive oxygen species before they can damage cells. (wikipedia.org)
- Objectives Vanadium (V) metal induces lipid peroxidation (LPO) and this has been proposed as a cause for its neurotoxicity. (thieme-connect.com)
- 3 Haider SS, el-Fakhri M. Action of alpha-tocopherol on vanadium-stimulated lipid peroxidation in rat brain. (thieme-connect.com)
- Microchromatographic analysis of lipids, protein, and occurrence of lipid peroxidation in various brain areas of vanadium exposed rats: a possible mechanism of vanadium neurotoxicity. (thieme-connect.com)
- Antioxidants provide protection to living organisms from damage caused by uncontrolled production of ROS and concomitant lipid peroxidation, protein damage and DNA stand breaking. (intechopen.com)
- Reactive oxygen species (ROS) can be generated when organisms are exposed to a material causing cellular responses, such as lipid peroxidation, H2O2 production, and DNA damage. (cdc.gov)
- We used electron spin resonance, analysis of lipid peroxidation, measurement of H2O2 production, and the comet assay to assess generation of ROS from SiNW and define possible mechanisms. (cdc.gov)
- Similarly, significant increase in Lipid Peroxidation (LPO) level while induced significant decreases in the activities of liver Catalase (CAT) and Glutathione-S-Transferase (GST). (scialert.net)
- Silymarin protects against its toxic principle α-amanitin by preventing its uptake through hepatocyte membranes and inhibiting the effects of tumour necrosis factor-α, which exacerbates lipid peroxidation. (springer.com)
- The induction of oxidative stress is shown by increased levels of lipid peroxidation, total peroxide, superoxide anion and lipoxygenase activity. (unboundmedicine.com)
- Sperm cell membranes are high in polyunsaturated fatty acids and are sensitive to oxygen free radical induced damage mediated by lipid peroxidation. (scialert.net)
- However, spermatozoa's lipids are the main substrates for peroxidation, which may provoke severe functional disorder of sperm. (scialert.net)
- Relationship between serum lipid peroxidation products in hypercholesterolemic subjects and vitamin E status. (vitalraadet.dk)
- Lipid peroxidation and changes in vitamin E levels during coronary artery bypass grafting. (vitalraadet.dk)
- The approach has the advantage of preventing the harmful accumulation of reactive oxygen species (ROS) by inhibiting the propagation of lipid peroxidation while antioxidants potentially neutralize beneficial oxidative species. (curefa.org)
- The thyroid is derived both embryoge- protects the cells against lipid peroxidation. (who.int)
- Change in oxidative stress biomarkers levels: lipid peroxidation index, nitric oxide metabolites, hydrogen peroxide (H2O2), superoxide anion radical (O2-), and glutation (GSH), catalasis(CAT) and superoxid dismutasis(SOD). (who.int)
- At what concentration does hydrogen peroxide inhibit enzyme activity? (researchgate.net)
- I am trying to measure GUS expression, and was wondering if anyone knew what concentration hydrogen peroxide inhibits the GUS protein? (researchgate.net)
- superoxide anion is then converted to oxygen and hydrogen peroxide by superoxide dismutase (SOD). (dojindo.com)
- Hydrogen peroxide is reduced to water by catalase or glutathione peroxidase. (dojindo.com)
- However, if hydrogen peroxide is not completely reduced by these enzymes, it can generate an extremely reactive hydroxy radical when oxidized by iron (Fenton reaction). (dojindo.com)
- Hypochlorite ion, an ROS derived from hydrogen peroxide by myeloperoxidase in neutrophils, has germicidal activity. (dojindo.com)
- Hydroxy radicals, which are produced from superoxide anion and hydrogen peroxide by the Fenton reaction, cause multiple modifications in DNA. (dojindo.com)
- SOD catalyzes the dismutation of the superoxide anion into molecular oxygen and hydrogen peroxide, which are much less oxidatively reactive. (dojindo.com)
- Hydrogen Peroxide For Acne: Is It Safe To Put On Your Skin? (mindbodygreen.com)
- When it comes to hydrogen peroxide, images of removing stains and the occasional scraped knee may come to mind. (mindbodygreen.com)
- Using hydrogen peroxide for acne might seem like the do-it-all solution you can snag at your local drugstore, but is it really safe to put on your skin? (mindbodygreen.com)
- What is hydrogen peroxide, and what does it do for acne? (mindbodygreen.com)
- Hydrogen peroxide is typically used for cleaning wounds-remember that handy brown bottle in your medicine cabinet? (mindbodygreen.com)
- According to board-certified dermatologist Hadley King, M.D. , hydrogen peroxide should definitely not be your primary treatment for acne. (mindbodygreen.com)
- Hydrogen peroxide versus benzoyl peroxide. (mindbodygreen.com)
- They're actually made up of entirely different compounds: "Benzoyl peroxide is lipid-soluble, while hydrogen peroxide is water-soluble," says King. (mindbodygreen.com)
- Hydrogen peroxide, on the other hand, is an effective disinfectant, but it doesn't have a similar track record in terms of breakouts. (mindbodygreen.com)
- Benzoyl peroxide does have its drawbacks as well (it can lead to redness, stinging, and peeling for some, says Downie), but derms favor the solution over hydrogen peroxide any day. (mindbodygreen.com)
- So here's the thing: Hydrogen peroxide wipes out all the bacteria-including the good kind. (mindbodygreen.com)
- creases hydrogen peroxide levels [ 7 ]. (who.int)
- In comparison to quercetin and ascorbic acid, the scavenging of superoxide radical (SOR), hydrogen peroxide, and 2, 2-Diphenyl-2-picrylhydrazyl (DPPH) radical activity by a model (most biologically active) of the anticancer plant was also evaluated. (who.int)
- Peroxides produced in the presence of a free radical by the oxidation of unsaturated fatty acids in the cell in the presence of molecular oxygen. (uams.edu)
- The lipid peroxide-mediated oxidation was demonstrated by using human low-density lipoprotein (LDL) in pH 7.4 phosphate buffer and by inhibiting the oxidation with ascorbic acid or l-glutathione, two antioxidants effective in both plasma and the LDL incubation. (diva-portal.org)
- A nucleophilic mechanism for the epoxidation of AZD9819 by lipid hydroperoxides explains the prevention of its ex vivo oxidation by acidification of the plasma samples. (diva-portal.org)
- The discovery of the lipid peroxide-dependent oxidation of an analyte and the means of prevention could provide valuable information for biotransformation and bioanalysis. (diva-portal.org)
- Plasma lipoprotein, plasma lipid peroxide, and LDL oxidation studies were performed every 6 weeks. (mapi.com)
- Chemical evidence of lipid oxidation is apparent at all stages of atherosclerosis, especially in macrophage-rich and early atherosclerotic lesions. (medscape.com)
- Ferroptosis-inducing factors can directly or indirectly affect glutathione peroxidase through different pathways, resulting in a decrease in antioxidant capacity and accumulation of lipid reactive oxygen species (ROS) in cells, ultimately leading to oxidative cell death. (nature.com)
- In 2012, Dixon 1 first proposed the concept of ferroptosis, an iron-dependent, non-apoptotic mode of cell death characterized by the accumulation of lipid reactive oxygen species (ROS). (nature.com)
- Death of GSCs was apparently due to the iron dependent form of programmed cell death characterized by the accumulation of lipid peroxides called ferroptosis. (nature.com)
- Deuterated trilinolenin [D-TG(54:9)] was sufficient to prevent the accumulation of lipid peroxides and to reduce the accumulation or ROS. (curefa.org)
- Effects of a 50 Hz electric field on plasma lipid peroxide level and antioxidant activity in rats med. (emf-portal.org)
- These results indicated that mulberry liquor is the most effective among the four mulberry products for normalizing blood glucose and lipid status and that all the mulberry products were effective in enhancing antioxidant defense in the diabetic state. (koreamed.org)
- Objective: To know the effect of vitamin C and vitamin E supplementation on peroxide lipid (MDA) of lactating women. (ugm.ac.id)
- Vitamin E appears to enhance lymphocyte proliferation, decrease the production of immunosuppressive prostaglandin E2, and decrease levels of immunosuppressive serum lipid peroxides. (medscape.com)
- Vitamin E supplementation, plasma lipids and incidence of restenosis after percutaneous transluminal coronary angioplasty PTCA. (vitalraadet.dk)
- If the oil is of low quality in terms of high peroxide levels (5.8 mEQ/kg) losses of vitamin A can reach 26% in the semi dark in 4 weeks compared with 0.7% at a PV of 0.4 mEq/kg (Laillou et.al, Food Nutr. (who.int)
- Allakhverdiev SI, Nishiyama Y, Suzuki I, Tasaka Y, Murata N (1999) Genetic engineering of the unsaturation of fatty acids in membrane lipids alters the tolerance of Synechocystis to salt stress. (springer.com)
- Once cleaved from the lipid membrane by the action of phospholipases they can circulate into various bodily fluids and eventually be excreted. (bvsalud.org)
- Fig. 3 Serum lipid levels of normal, diabetic control and the four mulberry groups after twenty four days of experimental diet period. (koreamed.org)
- The levels of plasma lipid peroxide did not change significantly. (mapi.com)
- Plasma tocopherol levels vary with total plasma lipid levels. (msdmanuals.com)
- They may contain small amounts of other lipids such as phosphatides, unsaponifiable constituents and free fatty acids naturally present in the ghee or oil. (who.int)
- Chemical transformations in acid rain : investigation of kinetics and mechanism of aqueous-phase peroxide formation. (epa.gov)
- Existing studies have confirmed that ferroptosis involves the metabolisms of the Fe, lipids, amino acid, each mechanism is mutually independent but interrelated, and they are formed a complex regulatory network. (frontiersin.org)
- RÉSUMÉ L'objectif de la présente étude était d'évaluer l'efficacité d'un programme d'exercice sur tapis roulant électronique sur le malondialdéhyde, en tant que marqueur de la peroxydation lipidique et sur une enzyme antioxydante, le glutathion peroxydase, chez des adolescents atteints du Syndrome de Down. (who.int)
- Is iron necessary to promote the production of lipid peroxides, or can other substances take the place of iron in ferroptosis? (nature.com)
- This battery of measurements are used in the diagnosis and treatment of certain liver, heart, and kidney diseases, acid-base imbalance in the respiratory and metabolic systems, other diseases involving lipid metabolism and various endocrine disorders as well as other metabolic or nutritional disorders. (cdc.gov)
- GH and/or IGF-I did not change the basal level of oxidative damage to lipids. (nel.edu)
- An unexpected lipid peroxide-mediated epoxidation followed by a dramatic rearrangement led to production of a five-membered oxazole derivative from the original six-membered pyrazinone-carboxamide core of a human neutrophil elastase inhibitor, 6-(1-(4-cyanophenyl)-1H-pyrazol-5-yl)-N-ethyl-5-methyl-3-oxo-4-(3-(trifluoromethyl)phenyl)-3,4-dihydropyrazine-2-carboxamide (AZD9819). (diva-portal.org)
- so at higher MDA, the lipid peroxidase production increases and causes turbidity [ 10 ]. (hindawi.com)
- [17] Exposure to ultraviolet (UV) radiation can cause direct photooxidation and decompose peroxides and carbonyl molecules. (wikipedia.org)
- Such fats and oils may contain traces or small amounts of other lipid such as phosphatides, unsaponifiable constituent's free fatty acid and other breakdown by products of the ghee or oil. (who.int)
- This graph shows the total number of publications written about "Lipid Peroxides" by people in UAMS Profiles by year, and whether "Lipid Peroxides" was a major or minor topic of these publications. (uams.edu)
- The formation of lipid peroxides results in the destruction of the original lipid leading to the loss of integrity of the membranes. (uams.edu)
- The study aim was to investigate the effects of three types of mulberry products on the blood glucose and lipid statuses and peroxidative state under diabetic condition. (koreamed.org)
- it even has the potential to bleach the skin (peroxide has the ability to bleach fabrics, after all), so those with darker skin tones should be extra careful. (mindbodygreen.com)