• involve
  • To limit the risk of prenatal radiation exposure as a trigger for leukemia (especially ALL), women who are pregnant or who suspect that they might be pregnant should always inform their doctors before undergoing tests or medical procedures that involve radiation (such as X-rays). (kidshealth.org)
  • closely related
  • Similar to the closely related pediatric disease juvenile myelomonocytic leukemia (JMML), a large fraction of CMML cases display hypersensitivity to granulocyte macrophage colony-stimulating factor (GM-CSF) in vitro, which likely contributes to the monocytosis characteristic of the disease [ 11-13 ]. (uptodate.com)
  • Cutis
  • Leukemia cutis is the infiltration of neoplastic leukocytes or their precursors into the skin resulting in clinically identifiable cutaneous lesions. (wikipedia.org)
  • aggressive
  • CMML is among the most aggressive chronic leukemias, and there are fewer effective therapies than for most other hematologic malignancies. (uptodate.com)
  • Aggressive NK-cell leukemia is a disease with an aggressive, systemic proliferation of natural killer cells (NK cells) and a rapidly declining clinical course. (wikipedia.org)
  • progresses
  • As leukemia progresses, the cancer interferes with the body's production of other types of blood cells, including red blood cells and platelets. (kidshealth.org)
  • cancers
  • As a group, leukemias account for about 30% of all childhood cancers and affect more than 3,000 American young people each year. (kidshealth.org)
  • With acute leukemias, children who are free of the disease after 5 years are very likely to have been cured, because it's very rare for these cancers to return after this long. (cancer.org)
  • cell
  • Chronic myelomonocytic leukemia (CMML) is a malignant hematopoietic stem cell disorder with clinical and pathological features of both a myeloproliferative neoplasm (MPN) and myelodysplastic syndrome (MDS). (uptodate.com)
  • It is divided in two main categories: T-cell LGL leukemia (T-LGLL) and natural-killer (NK)-cell LGL leukemia (NK-LGL)L. As the name suggests, T-cell large granular lymphocyte leukemia is characterized by involvement of cytotoxic-T cells). (wikipedia.org)
  • The postulated cells of origin of T-LGLL leukemia are transformed CD8+ T-cell with clonal rearrangements of β chain T-cell receptor genes for the majority of cases and a CD8- T-cell with clonal rearrangements of γ chain T-cell receptor genes for a minority of cases. (wikipedia.org)
  • This condition may be contrasted with leukemids, which are skin lesions that occur with leukemia, but which are not related to leukemic cell infiltration. (wikipedia.org)
  • The requirements for diagnosing ANKL are as follows: Immature-looking NK cells Certain immunophenotypes Germline configuration genes: TCR-β and IgH Restricted cytotoxicity The T-cell receptor (TCR) is an important factor when ANKL is being diagnosed along with T-cell leukemia. (wikipedia.org)
  • Treatment
  • Immediate treatment is required in acute leukemia because of the rapid progression and accumulation of the malignant cells, which then spill over into the bloodstream and spread to other organs of the body. (wikipedia.org)
  • Whereas acute leukemia must be treated immediately, chronic forms are sometimes monitored for some time before treatment to ensure maximum effectiveness of therapy. (wikipedia.org)
  • What was the treatment for your leukemia? (medicinenet.com)