• type
  • Hairy-cell leukemia is a type of cancer in which too many abnormal immune cells are produced. (unm.edu)
  • It is considered a slow-growing type of leukemia that occurs more commonly in older men. (unm.edu)
  • A genetic mutation referred to as the BRAF V600E mutation is thought to be an involved the excessive replication of hairy cell leukemia, as it is a common mutation in this type of cancer. (unm.edu)
  • patients
  • The targeted agent, Zelboraf┬« (vemurafenib), which is approved for the treatment of melanoma, provided high anti-cancer activity among patients with hairy-cell leukemia that had stopped responding to prior therapies. (unm.edu)
  • Researchers from Italy and the United States conducted clinical trials to evaluate Zelboraf among patients with hairy cell leukemia that had stopped responding to prior standard therapy. (unm.edu)
  • Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to Fanconi anemia in patients with acute myeloid leukemia. (clinicaltrials.gov)