• chromosome
  • MLL5, a homolog of Drosophila trithorax located within a segment of chromosome band 7q22 implicated in myeloid leukemia," Oncogene , vol. 21, no. 31, pp. 4849-4854, 2002. (hindawi.com)
  • bone
  • Note the small number of B-cell precursors in normal bone marrow relative to the large abnormal B-cell population lacking CD45 expression (bottom left) in the patient with leukemia. (asmscience.org)
  • Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cells. (wikipedia.org)
  • The underlying mechanism involves replacement of normal bone marrow with leukemia cells, which results in a drop in red blood cells, platelets, and normal white blood cells. (wikipedia.org)
  • Rarely, the first sign of leukemia may be the development of a solid leukemic mass or tumor outside of the bone marrow, called a chloroma. (wikipedia.org)
  • Leukemias and lymphomas both belong to a broader group of tumors that affect the blood, bone marrow, and lymphoid system, known as tumors of the hematopoietic and lymphoid tissues. (wikipedia.org)
  • Symptoms
  • Occasionally, a person may show no symptoms, and the leukemia may be discovered incidentally during a routine blood test. (wikipedia.org)
  • infection
  • Mucormycosis is a rare and acute fungal infection which is frequently lethal, usually observed in non-controlled diabetic patients. (pubfacts.com)
  • present
  • CEBPA-associated familial acute myeloid leukemia (AML) is defined as AML in which a heterozygous germline CEBPA pathogenic variant is present in a family in which multiple individuals have AML. (nih.gov)
  • In 2015, leukemia was present in 2.3 million people and caused 353,500 deaths. (wikipedia.org)