• Lymphoma
  • Leukemia & Lymphoma. (wikipedia.org)
  • Moreover, co-expression of the interleukin-7 receptor together with LNK was carefully studied, and it was concluded that interleukin-7 receptor expression was significantly more highly expressed than LNK in B-cell acute leukemic lymphoma. (wikipedia.org)
  • This observation distinguished a novel subset of high-risk B-cell acute lymphoblastic lymphoma with a potential therapy targeting the interleukin-7 signaling pathway. (wikipedia.org)
  • Mitoxantrone
  • I. To estimate the maximum tolerated dose (MTD) and examine the tolerability of daily oral eltrombopag (eltrombopag olamine) (14 days +/- 2 days after initiation of cytarabine) in patients receiving high dose cytarabine and mitoxantrone for the treatment of acute myeloid leukemia patients with hypoplastic bone marrow 14 days +/- 2 days from initiation of cytarabine. (knowcancer.com)
  • 100 x 10^9/L when eltrombopag is administered following high dose cytarabine and mitoxantrone for the treatment of acute myeloid leukemic patients. (knowcancer.com)
  • Mast
  • In a small proportion of cases, acute mast cell leukemia may evolve from a more progressive form of systemic mastocytosis. (wikipedia.org)
  • The diagnosis of acute mast cell leukemia by the WHO criteria includes the requirement for a prevalence of 20% neoplastic mast cells in marrow and 10% in blood. (wikipedia.org)
  • If the mast cells represent less than 10% of blood cells, the tumor is called "aleukemic" mast cell leukemia. (wikipedia.org)
  • Acute mast cell leukemia is a rapidly progressive disorder with leukemic mast cells in blood and in large numbers in marrow. (wikipedia.org)
  • The typical cutaneous mast cell infiltrates of urticaria pigmentosa are usually not present before, during, or after diagnosis in patients who have mast cell leukemia. (wikipedia.org)
  • Total serum tryptase is elevated in mast cell leukemia. (wikipedia.org)
  • Normal total(alpha + beta) serum tryptase is approximately 6 micro g/L (range 0 to 11 micro g/L). Values of several hundred micro g/L are characteristic of mast cell leukemia. (wikipedia.org)
  • Plasma and urinary histamine levels are frequently elevated in mast cell leukemia. (wikipedia.org)
  • Measurement of histidine carboxylase in the marrow cells of patients with mast cell leukemia is a very sensitive marker of mast cells. (wikipedia.org)
  • Immunotherapy with anti-IgE immunoglobulin raised in sheep resulted in a transient decrease in the numbers of circulating mast cells in one patient with mast cell leukemia. (wikipedia.org)
  • Although splenectomy has led to brief responses in patients with mast cell leukemia, no firm conclusions as to the efficacy of this treatment are possible. (wikipedia.org)
  • Acute mast cell leukemia is extremely aggressive and has a grave prognosis. (wikipedia.org)
  • leukemic
  • I. Determine effect of treatment with the combination on time to response, time to leukemic transformation and frequency of transformation to leukemia in patients with MDS during the phase II segment of the study. (knowcancer.com)
  • Leukemic transformation can occur in any of these two cells, but transformation of myeloid dendritic cell is less common and it leads to a form of leukemia known as acute myeloid dendritic cell leukemia. (wikipedia.org)
  • phase
  • During the beginning (acute) phase of inflammation, particularly as a result of bacterial infection, environmental exposure, and some cancers, neutrophils are one of the first-responders of inflammatory cells to migrate towards the site of inflammation. (wikipedia.org)
  • Remission
  • Long-lasting remissions have been documented in sporadic cases, usually occurring in young patients who have been treated with acute leukemia-type induction therapy, followed by allogenic HSCT in first complete remission. (wikipedia.org)
  • Secondary
  • 10.Acute interstitial nephritis secondary to deferasirox causing acute renal injury needing short-term dialysis. (edu.au)
  • Adult
  • This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the treatment of adult acute myeloid leukemia. (uchile.cl)
  • progenitor
  • Patients with leukemias that express the progenitor cell antigen CD34 and/or the P-glycoprotein (MDR1 gene product) have an inferior outcome. (uchile.cl)