• degenerative
  • The paracrine soluble factors produced by stem cells, known as the stem cell secretome, has been found to be the predominant mechanism by which stem cell-based therapies mediate their effects in degenerative, auto-immune and inflammatory diseases. (wikipedia.org)
  • When he was nine years old, he was diagnosed with a degenerative hip disease, called Legg-Calve-Perthes, that confined him to a full leg brace and crutches for two years, and made it impossible for him to play sports. (wikipedia.org)
  • diagnosis
  • There are no set standards for the diagnosis of suspected transient synovitis, so the amount of investigations will depend on the need to exclude other, more serious diseases. (wikipedia.org)
  • limp
  • The area becomes intensely inflamed and irritated and your child may begin to show signs of the disease, such as a limp or different way of walking. (aaos.org)
  • include
  • The disease is theorized to include the artery of the ligmentum teres femoris being constricted or even blocked too early, not allowing for time when the medial circumflex femoral artery takes over. (wikipedia.org)
  • Conditions
  • They can suffer from hip dysplasia and elbow dysplasia as well as hypothyroidism, von Willebrand's disease, and thrombopathia, and should be assessed for all of these conditions. (wikipedia.org)
  • Research is underway to develop various sources for stem cells, and to apply stem-cell treatments for neurodegenerative diseases and conditions such as diabetes, heart disease, and other conditions. (wikipedia.org)
  • often
  • The reossification stage is often the longest stage of the disease and can last a few years. (aaos.org)
  • studies
  • Some recent studies indicate that there may be a genetic link to the development of Perthes, but more research needs to be conducted. (aaos.org)
  • research
  • Research has been conducted on the effects of stem cells on animal models of brain degeneration, such as in Parkinson's, Amyotrophic lateral sclerosis, and Alzheimer's disease. (wikipedia.org)
  • The Orthopedic Foundation for Animals (OFA) is a not-for-profit organization based in Columbia, Missouri that aims to research and prevent orthopedic and hereditary diseases in companion animals. (wikipedia.org)
  • As a private not-for-profit foundation, the OFA has funded nearly $3 million in research aimed at reducing the incidence and prevalence of inherited companion animal disease. (wikipedia.org)
  • OFA supported research is not limited to orthopedic disease, and has included cancers, heart disease, and thyroid disease as examples. (wikipedia.org)