• Lactoperoxidase catalyzes the hydrogen peroxide (H2O2) oxidation of several acceptor molecules: reduced acceptor + H2O2 → oxidized acceptor + H2O Specific examples include: thiocyanate (SCN−) → hypothiocyanite (OSCN−) bromide (Br−) → hypobromite (BrO−) iodide (I−) → hypoiodite (IO−) Source of the hydrogen peroxide (H2O2) usually is the reaction of glucose with oxygen in the presence of the enzyme glucose oxidase (EC 1.1.3.4) that also takes place in saliva. (wikipedia.org)
  • A combination of lactoperoxidase, glucose, glucose oxidase (GOD), iodide and thiocyanate is claimed to be effective in the preservations of cosmetics. (wikipedia.org)
  • Antibody conjugates of glucose oxidase and to lactoperoxidase have been found to effective in killing tumor cells in vitro. (wikipedia.org)
  • MQuant ® test strips are used for the semiquantitative screening of glucose, lactoperoxidase in pasteurized milk, and detection of ascorbic acid and lactic acid in fruits, among others. (sigmaaldrich.com)
  • These relatively short lived oxidized intermediates have potent bactericidal effects, hence lactoperoxidase is part of the antimicrobial defense system in tissues that express lactoperoxidase. (wikipedia.org)
  • In its antimicrobial capacity, lactoperoxidase appears to acts synergistically with lactoferrin and lysozyme. (wikipedia.org)
  • Lactoperoxidase is an effective antimicrobial and antiviral agent. (wikipedia.org)
  • Lactoperoxidase is an effective antimicrobial agent and is used as an antibacterial agent in reducing bacterial microflora in milk and milk products. (wikipedia.org)
  • The most vital role of lactoperoxidase is to oxidize thiocyanate ions (SCN−) found in saliva in the presence of hydrogen peroxide resulting in products that show antimicrobial activity. (phcoker.com)
  • Lactoperoxidase is an enzyme with antimicrobial ability. (adpi.org)
  • In humans, lactoperoxidase is encoded by the LPO gene. (wikipedia.org)
  • In human beings, the lactoperoxidase enzyme is encoded by the LPO gene. (phcoker.com)
  • Should we expect to see the lactoferrin and lactoperoxidase markets being measured in kt soon? (girafood.com)
  • Effects of lactoferrin and lactoperoxidase-containing food on the oral microbiota of older individuals. (bvsalud.org)
  • Bioactive compounds like immunoglobulins, lactoferrin, and lactoperoxidase might sound like tongue twisters. (ultimatenutrition.com)
  • A fractionated whey protein with high levels of lactoferrin and lactoperoxidase to support a pet's immune system, growth, and well-being. (glanbianutritionals.com)
  • Lactoperoxidase preservative can be used to preserve raw milk obtained from different species. (phcoker.com)
  • The enzyme (lactoperoxidase) has been used as an activating agent to reduce peroxide concentration in order to minimize the risk of undesirable effects [ 13 ]. (hindawi.com)
  • and enzyme lactoperoxidase. (wintersun.com)
  • The lactoperoxidase system plays an important role in the innate immune system by killing bacteria in milk and mucosal (linings of mostly endodermal origin, covered in epithelium, which are involved in absorption and secretion) secretions hence augmentation of the lactoperoxidase system may have therapeutic applications. (wikipedia.org)
  • Activation of the lactoperoxidase system by addition of hydrogen peroxide and thiocyanate extends the shelf life of refrigerated raw milk. (wikipedia.org)
  • The ability of the lactoperoxidase in the maintenance of the pure quality of raw milk for a given period of time has been established in several fields and experimental studies carried out in various geographical regions. (phcoker.com)
  • Lactoperoxidase exerts a bacteriostatic effect in mammal's raw milk. (phcoker.com)
  • At the minimum end of the temperature scale, different studies show that activation of lactoperoxidase can delay psychrotrophic's milk bacteria growth and thus delay spoilage of milk for more days compared to refrigeration alone. (phcoker.com)
  • It is crucial to note that the purpose of using lactoperoxidase is not to make the milk safe for consumption but to preserve its original quality. (phcoker.com)
  • Practicing good hygiene in the production of milk is crucial to the lactoperoxidase efficacy and to the microbiological milk quality. (phcoker.com)
  • The safety and freshness of milk can only be achieved through a combination of heat treatment of milk and good hygienic practices independent of using lactoperoxidase. (phcoker.com)
  • Benefits and potential risks of the lactoperoxidase system of raw milk preservation : report of an FAO/WHO technical meeting, FAO Headquarters, Rome, Italy, 28 November - 2 December 2005. (who.int)
  • Consequently, applications of lactoperoxidase are being found in preserving food, cosmetics, and ophthalmic solutions. (wikipedia.org)
  • Lactoperoxidase application is thereby found mainly in food preservation, ophthalmic solutions, and cosmetic purposes. (phcoker.com)
  • In particular, in highly viscous concentrated solutions, water activity, which is a thermodynamical variable extensively used to describe the chemical potential of water in binary and complex systems, could play a significant role [5].The aim of this study was to investigate and compare the effect of viscosity and water activity (aw) on the activity of horseradish peroxidase (HRP) and bovine lactoperoxidase (LPO) in buffered solutions. (unite.it)
  • Molecular cloning of cDNAs encoding bovine and human lactoperoxidase. (rusmedserv.com)
  • However, under certain conditions, the lactoperoxidase system may contribute to oxidative stress. (wikipedia.org)
  • Here, we review the role and contribution of different oxidative enzymes of inflammatory cells - myeloperoxidase, eosinophil peroxidase, lactoperoxidase, hemoglobin, and xanthine oxidase - to the reactions of nanoparticle biodegradation. (cdc.gov)
  • Lactoperoxidase is a peroxidase enzyme secreted from mammary, salivary and other mucosal glands including the lungs, bronchii and nose that functions as a natural and the first line of defense against bacteria and viruses. (wikipedia.org)
  • Lactoperoxidase is a member of the heme peroxidase family of enzymes. (wikipedia.org)
  • Lactoperoxidase belongs to the heme peroxidase family of mammalian enzymes that also includes myeloperoxidase (MPO), eosinophil peroxidase (EPO), thyroid peroxidase (TPO), and prostaglandin H synthase (PGHS). (wikipedia.org)
  • Lactoperoxidase is simply a peroxidase enzyme produced from the mucosal, mammary, and salivary glands, which works as a natural anti-bacterial agent. (phcoker.com)
  • Studies have shown that in addition to having antiviral effects, Lactoperoxidase can also protect animal cells from various damages and peroxidation, and it is also an important component of the defense system against pathogenic microorganisms in the digestive system of newborn infants. (phcoker.com)
  • Finally lactoperoxidase may find application as anti-tumor and anti viral agents. (wikipedia.org)
  • Lactoperoxidase has been used in toothpaste or a mouthrinse to reduce oral bacteria and consequently the acid produced by those bacteria. (wikipedia.org)
  • The aim of this clinical study was to evaluate the effectiveness of a whitening toothpaste containing 3% carbamide peroxide and lactoperoxidase. (hindawi.com)
  • During the last years, a bleaching toothpaste containing 3% CP and 5% lactoperoxidase has been developed [ 13 ]. (hindawi.com)
  • The aim of this study was to evaluate the bleaching efficacy of a bleaching toothpaste containing 3% CP and 5% lactoperoxidase and to assess its possible side-effects on the oral soft tissues. (hindawi.com)
  • Modern oral hygiene products are being enriched with the lactoperoxidase system to offer an excellent alternative to the standard fluoride toothpaste. (phcoker.com)
  • These substrates include bromide and iodide and therefore lactoperoxidase can be categorised as a haloperoxidase. (wikipedia.org)
  • Research (1984): "The effect of lactoperoxidase-thiocyanate-hydrogen peroxide mixtures on bacteria is dependent on experimental conditions. (wikipedia.org)
  • If the bacteria are cultured after the exposure to lactoperoxidase-thiocyanate-hydrogen peroxide on nutrient agar under aerobic conditions, they may not grow, whereas they grow readily on blood agar under anaerobic conditions. (wikipedia.org)
  • Lactoperoxidase (LPO) , which is found in salivary and mammary glands, is a crucial element of the immune response important in maintaining good oral health. (phcoker.com)
  • 2006 . Simulated moving bed with a simplified approach for protein purification: Separation of lactoperoxidase and lactoferrin from whey protein concentrate. (lu.se)
  • This Lactoperoxidase antibody is useful for Western blot analysis where a band is seen at ~100 kDa. (thermofisher.com)
  • Furthermore, addition or augmentation of the lactoperoxidase system has potential applications in controlling bacteria in food and consumer health care products. (wikipedia.org)
  • Lactoperoxidase kills the Gram-negative bacteria and prevents the growth and development of Gram-positive bacteria. (phcoker.com)
  • Furthermore, lactoperoxidase have found application in dental and wound treatment. (wikipedia.org)
  • Also, lactoperoxidase powder has been used in wound and dental treatment. (phcoker.com)
  • Furthermore, lactoperoxidase may contribute to the initiation of breast cancer, through its ability to oxidize estrogenic hormones producing free radical intermediates. (wikipedia.org)
  • Lactoperoxidase together with its inorganic ion substrates, hydrogen peroxide, and oxidized products is known as the lactoperoxidase system. (wikipedia.org)
  • The lactoperoxidase system does not attack DNA and is not mutagenic. (wikipedia.org)
  • The lactoperoxidase system is effective in killing a range of aerobic and certain anaerobic microorganisms. (wikipedia.org)
  • A lactoperoxidase system is claimed to appropriate for the treatment of gingivitis and paradentosis. (wikipedia.org)
  • Synthetic peptide corresponding to a C-terminal portion (within residues 650-712) of human Lactoperoxidase. (thermofisher.com)
  • Lactoperoxidase function here is to cause a chain of reactions leading to the consumption of oxygen and accumulation of intracellular hydrogen peroxide. (phcoker.com)
  • The lactoperoxidase/glucoseoxidase technique was the labelling method of choice leading to immunoreactive IL-2 with high specific activity. (nih.gov)
  • Lactoperoxidase cancer management ability is associated with its ability to oxidize estradiol. (phcoker.com)
  • Because of the broad applications of the lactoperoxidase supplement , its demand has increased significantly over the years, and it is still growing. (phcoker.com)
  • Research data and experience from real practice show that lactoperoxidase can be used beyond the temperature limits of (15-30 degrees Celsius) referred to in the codex guidelines of 1991. (phcoker.com)