Kidney tubular necrosis acute. Medical search. Frequent questions

Acute interstitial nephritis (AIN) is inflammation of the renal interstitium leading to acute renal dysfunction. (logicalimages.com)
Additionally, disturbance in acid-base, electrolytes and fluid balance are usually related to a marked decline in the glomerular filtration rate (GFR) caused by a variety of systemic diseases such as diabetes mellitus or hypertension, and renal disorders as chronic glomerulonephritis,cystic kidney disorder,interstitial nephritis, obstructive uropathy, and lupus nephritis. (intechopen.com)
Renal AKI describes the conditions which affect the glomerulus or tubule, for example, acute tubular necrosis and acute interstitial nephritis. (randox.com)
Overview of Tubulointerstitial Diseases Tubulointerstitial diseases are clinically heterogeneous disorders that share similar features of tubular and interstitial injury. (merckmanuals.com)
Chronic tubulointerstitial nephritis (CTIN) arises when chronic tubular insults cause gradual interstitial infiltration and fibrosis, tubular atrophy and dysfunction, and a gradual deterioration of renal function, usually over years. (merckmanuals.com)

Chronic lead poisoning may also result in lead nephropathy, which is characterized by tubulointerstitial fibrosis, tubular atrophy, glomerular sclerosis, and ultimately diminished glomerular filtration rate (GFR). (medscape.com)
Removal of lead using chelation therapy reverses the proximal reabsorptive defect and removes the intranuclear inclusion bodies of acute lead nephropathy. (medscape.com)
Treatment history for longstanding acute kidney pathology , Glomerular disease acute tubular necrosis, nephritic syndrome, nephritic syndrome , membranous nephropathy etcâ? (who.int)

Sepsis also can directly damage kidney cells, which worsens the effects of the low blood pressure caused by sepsis. (msdmanuals.com)
Tachypnea and hypoxia with impending respiratory failure may develop as a consequence of sepsis and acute respiratory distress syndrome (ARDS). (medscape.com)
Infections - to the kidney itself, or within the bloodstream (eg sepsis). (healthengine.com.au)
One of the most common and devastating morbidities is sepsis-related acute kidney injury (AKI). (bvsalud.org)
Immunohistochemistry at 24 h after the induction of sepsis demonstrated increased expression of OLFM4 in the kidney, which was localized to the loop of Henle. (bvsalud.org)

Necrotic cells fall into the tubule lumen, obturating it, and determining acute kidney failure. (wikipedia.org)

Overall, when ATN was absent, studies reported a wide variety of kidney morphologic changes in septic AKI - ranging from normal (in most cases) to marked cortical tubular necrosis. (biomedcentral.com)

The recovery phase, in which tubular function recovers, is characterized by an increase in urine volume (if oliguria was present during the maintenance phase) and by a gradual decrease in BUN and serum Cr to their preinjury levels. (medscape.com)
Acute tubular necrosis is kidney injury caused by damage to the kidney tubule cells (kidney cells that reabsorb fluid and minerals from urine as it forms). (msdmanuals.com)
Little or no urine is made, even though the kidney itself is working. (medlineplus.gov)
Leptospires live in the kidneys of reservoir animals and are shed in the urine, contaminating surface water. (mdpi.com)
Some of these include: the build up of waste products that the kidneys usually excrete, such as urea and creatinine, high or low concentrations of molecules such as sodium and potassium, low numbers of red blood cells, inability to concentrate the urine properly and build up of excess fluid. (healthengine.com.au)
This causes the urine to back up and injure one or both kidneys. (adam.com)
The success of graft survival after kidney transplantation is closely associated with early graft function based on intraoperative perfusion characteristics of the allograft and good urine output. (intechopen.com)
Qualitative urine immunoassays (ie, urine drug screens) are available for amphetamines but have limited utility in managing acute toxicity. (emra.org)
Acute Kidney Injury (AKI) Acute kidney injury is a rapid decrease in renal function over days to weeks, causing an accumulation of nitrogenous products in the blood (azotemia) with or without reduction in amount of urine. (merckmanuals.com)
Acute renal failure is sudden loss of the ability of the kidneys to excrete wastes, concentrate urine, and conserve electrolytes. (health.am)
Measurement of the urine sodium concentration is vital in determining the integrity of tubular reabsorptive function. (medscape.com)

Acute failure of the kidneys is a condition in which there is a rapid loss of the normal function of your kidneys, due to a sudden, acute or chronic insult. (healthengine.com.au)
10 µg/dL, increase the risk of chronic kidney disease (CKD), with decreased estimated glomerular filtration rate (eGFR) and creatinine clearance. (medscape.com)
The association between lead exposure and GFR was evaluated in North American children with CKD in the Chronic Kidney Disease in Children (CKiD) study. (medscape.com)
This review examines the evidence linking acute kidney injury (AKI) with the risk of subsequently developing chronic kidney disease (CKD). (karger.com)
Amongst the survivors of an episode of AKI, there is an increasing understanding of long-term consequences that may include an increased mortality risk, the development of chronic kidney disease (CKD), and the progression from CKD to end-stage renal disease (ESRD) [ 2,3 ]. (karger.com)
Chronic Kidney Disease Chronic kidney disease (CKD) is long-standing, progressive deterioration of renal function. (merckmanuals.com)
Disorders that cause acute kidney injury in early or late pregnancy generally fall into very different categories, and it must also be remembered that pregnancies in women with underlying chronic kidney disease who require dialysis during pregnancy or who have previously undergone renal transplantation pose unique sets of issues. (medscape.com)
Go to Hypertension and Pregnancy, Preeclampsia, Hypertension, and Chronic Kidney Disease for more information on these topics. (medscape.com)
Chronic Kidney Disease is an abnormal kidney function and/ or structure, present for a minimum period of 3 months. (randox.com)
Utilising patented Biochip Technology, the Randox Chronic Kidney Disease (CKD) arrays could improve patient risk stratification whilst monitoring the effectiveness of treatment. (randox.com)
Chronic Mg deficiency has also been shown to increase copper absorption and concentrations in plasma, muscle, kidney, and liver. (drsircus.com)

Acute-onset, severe hypertension that is accurately measured using standard techniques and is persistent for 15 minutes or longer is considered a hypertensive emergency. (medscape.com)
Intravenous (IV) labetalol and hydralazine have long been considered first-line medications for the management of acute-onset, severe hypertension in pregnant women and women in the postpartum period. (medscape.com)
4] The hypothesis was that decreased synthesis of eicosanoids might contribute to hypertension and make the kidney more vulnerable to drugs that reduce the synthesis of locally produced vasodilators (eg, nonsteroidal anti-inflammatory drugs). (medscape.com)
Disorders of the blood, such as idiopathic thrombocytopenic purpura (ITP), transfusion reaction, or other hemolytic disorders, malignant hypertension and disorders resulting from childbirth, such as bleeding placenta abruptio or placenta previa can damage the kidneys. (health.am)

Acute kidney injury (AKI) is one of the most serious complications, especially in end-stage liver disease. (hindawi.com)
Partly based on the AKIN and RIFLE criteria, Kidney Disease: Improving Global Outcomes (KDIGO) published the KDIGO standard for the evaluation and management of AKI in 2012. (hindawi.com)
2. What things can cause a change in the structure or function of the kidney, causing kidney disease? (weber.edu)
The incidence of kidney disease due to bacteria such as streptococci has been gradually decreasing with the increasing living standards in Australia. (healthengine.com.au)
However, in many Indigenous communities, high incidences of streptococcal infection and kidney disease are still seen. (healthengine.com.au)
Acute disease of the kidneys (acute glomerulonephritis ) due to: immune causes, development of antibodies and sometimes from unknown causes. (healthengine.com.au)
Kidney disease: improving global outcomes (KDIGO) Acute Kidney Injury Work Group. (bmj.com)
Hospitalization discharge diagnoses for kidney disease: United States, 1980-2005. (bmj.com)
2022 United States Renal Data System (USRDS) annual data report: epidemiology of kidney disease in the United States. (bmj.com)
Toxic nephropathies are estimated to cause fewer than 1% of all cases of end-stage kidney disease. (medscape.com)
Postoperative AKI within 72 hours was defined using the International Kidney Disease: Improving Global Outcomes classification. (bmj.com)
http://www.ncbi.nlm.nih.gov/pubmed/17715412?tool=bestpractice.com According to the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines, AKI severity is classified into three stages depending on the serum creatinine level or the extent of oliguria. (bmj.com)
Ideally, women with kidney disease or systemic diseases that would put them at risk during pregnancy should receive preconception counseling from physicians knowledgeable about the current literature related to pregnancy. (medscape.com)
Successful maternal and fetal outcomes for women with preexisting kidney disease, and those with onset of kidney disease during pregnancy, require a close working relationship among all physicians involved in the care of these patients. (medscape.com)
These changes are particularly important, as a normal serum creatinine or BUN level may represent kidney disease during pregnancy. (medscape.com)
Diagnosis of CKD at early stages will allow earlier intervention for the treatment of kidney disease, and the prevention of further kidney damage. (randox.com)
With the rise in the population of patients with End-stage Renal Disease (ESRD) in Nigeria, there is an increased demand for Renal Replacement Therapy (RRT) including kidney transplantation (KT). (lidsen.com)
Acute kidney injury (AKI) is a severe disease with high morbidity and mortality. (biomedcentral.com)
Kidney Disease and Quality of Life (KDQOL-SFTM) b. (who.int)
Background: Acute kidney injury (AKI) commonly occurs in coronavirus disease 2019 (COVID-19) patients who have been hospitalised and is associated with a poor prognosis. (bvsalud.org)

In addition, gold nanoshells did not induce any tissue damage, such as necrosis, inflammatory infiltrate or fibrosis in mouse liver, spleen, kidney or bone marrow after 6 months. (springer.com)
HGF is produced and secreted by adjacent stromal and mesenchymal cells, it contributes to the development of epithelial organs in a paracrine fashion, exerts regenerative effects on epithelia in the liver, kidney, lung, and other tissues, and promotes the regression of fibrosis in numerous organs ( 7 , 8 ). (spandidos-publications.com)

Given the unmet medical need to clinically inhibit AKI, we generated a combined small molecule inhibitor (Nec-1f) that simultaneously targets receptor interacting protein kinase 1 (RIPK1) and ferroptosis in cell lines, in freshly isolated primary kidney tubules and in mouse models of cardiac transplantation and of AKI and improved survival in models of ischemia-reperfusion injury. (illinois.edu)
Organ ischemia, which primarily affects the kidneys and central nervous system, leads to altered mental status and/or signs of volume overload. (medscape.com)
Recent studies have shown that ferroptosis is closely related to the pathophysiological processes of many diseases, such as tumors, nervous system diseases, ischemia-reperfusion injury, kidney injury, and blood diseases. (nature.com)
Ferroptosis plays an important regulatory role in the occurrence and development of many diseases, such as tumors, neurological diseases, acute kidney injury, ischemia/reperfusion, etc. (nature.com)
For example, if ATN was a consistent histopathological finding, this would strongly suggest that ischemia and tubular cell necrosis are probably an important pathogenetic mechanism. (biomedcentral.com)
Morbidity from shock may be widespread and can include central nervous system (CNS) failure, respiratory failure (ie, from muscle fatigue or acute respiratory distress syndrome [ARDS]), renal failure, hepatic dysfunction, gastrointestinal ischemia, disseminated intravascular coagulation (DIC), metabolic derangements, and ultimately death. (medscape.com)

In addition to the links below, review the urinary system, kidney anatomy, and the nephron in the workbook. (weber.edu)
Urinary tract obstruction, such as a narrowing of the urinary tract (stricture), tumors, kidney stones, nephrocalcinosis or enlarged prostate with subsequent acute bilateral obstructive uropathy. (health.am)

For patient education information, see Acute Kidney Failure . (medscape.com)
Prerenal azotemia is the most common form of kidney failure in hospitalized people. (medlineplus.gov)
Acute kidney failure resulting from destruction of EPITHELIAL CELLS of the KIDNEY TUBULES . (nih.gov)
RIFLE criteria include parameters present during the whole course of the condition, ranging from kidney injury to end-stage renal failure. (hindawi.com)
Acute renal failure (ARF) is a frequent tients who required kidney biopsy. (who.int)
Snakebite, malaria, liver diseases and Multivariate logistic regression analysis road traffic accidents are common health was carried out to study potential factors problems in Saudi Arabia [ 7-9 ], and the that might affect survival of acute renal contribution of these conditions to the de- failure. (who.int)
The link above presents a good overview of the key points of renal failure and links to basic kidney function. (weber.edu)
5. Define acute renal (kidney) failure. (weber.edu)
6. What symptoms may occur in acute kidney failure? (weber.edu)
7. What is prerenal acute renal failure and what might cause this? (weber.edu)
9. What causes intrarenal acute renal failure? (weber.edu)
Acute kidney failure should be treated as a serious condition and is a potential medical emergency. (healthengine.com.au)
Acute failure of the kidneys is not a rare condition, with the incidence depending on the definition used and the population studied. (healthengine.com.au)
People who are hospitalized in hospital intensive care units (ICUs) are at very high risk for acute kidney failure. (healthengine.com.au)
A large multinational study was recently published in 2005, which studied over 29000 ICU patients in multiple countries to try and determine the incidence of acute kidney failure. (healthengine.com.au)
Of the 29 269 critically ill patients admitted during the study period, approximately 6% developed acute renal failure during their ICU stay. (healthengine.com.au)
The most common causes of acute kidney failure are those conditions that cause reduced blood supply to the kidneys. (healthengine.com.au)
Generally, causes of acute kidney failure can be divided into three groups - pre-renal (ie affecting the body's volume and vessels supplying the kidneys, renal (within the kidney) and post renal (affecting pathways and structures after the kidneys). (healthengine.com.au)
Spectrum of acute renal failure in the intensive care unit: the PICARD experience. (bmj.com)
14. Liaño F, Pascual J. Epidemiology of acute renal failure: a prospective, multicenter, community-based study. (bmj.com)
Madrid Acute Renal Failure Study Group. (bmj.com)
Epidemiology and outcomes of acute renal failure in hospitalized patients: a national survey. (bmj.com)
17. Lameire N, Van Biesen W, Vanholder R. Acute renal failure. (bmj.com)
Hemodynamically mediated acute renal failure. (bmj.com)
Apoptotic pathways in ischemic acute renal failure. (bmj.com)
Acute kidney failure is the rapid (less than 2 days) loss of your kidneys' ability to remove waste and help balance fluids and electrolytes in your body. (adam.com)
Acute tubular necrosis (ATN) is a kidney disorder involving damage to the tubule cells of the kidneys, which can lead to acute kidney failure. (adam.com)
Kidney transplantation results in superior life expectancy and better quality of life if compared to dialysis treatment for patients with end-stage renal failure. (intechopen.com)
The United States Renal Data System discloses that 2-3% of incident ESRD patients in the US have acute tubular necrosis (ATN) as the primary etiology for renal failure, and this percentage rises when considering other separately coded forms of AKI [ 3 ]. (karger.com)
Autoimmune disorders such as scleroderma can cause acute renal failure. (health.am)
In young children, hemolytic uremic syndrome is an increasingly common cause of acute renal failure. (health.am)
Examination and testing can reveal acute renal failure and help rule out other disorders that affect kidney function. (health.am)
Kidney or abdominal ultrasound is usually the best test, but abdominal X-ray, abdominal CT scan or abdominal MRI may also reveal the cause of acute renal failure. (health.am)
Shock is defined as a state of acute energy failure due to inadequate glucose substrate delivery, oxygen delivery, or mitochondrial failure at the cellular level. (medscape.com)

People have no symptoms unless kidney injury is severe. (msdmanuals.com)
Symptoms are related to the cause of AIN and to the degree of acute kidney injury. (logicalimages.com)
3. List symptoms that may be present if the kidneys are failing? (weber.edu)

Liver function tests (LFTs): Elevated levels of transaminases precede the appearance of jaundice, and the degree of liver dysfunction in the acute phase may be predictive of the clinical course. (medscape.com)
An intrinsic acute kidney injury caused by ischemic or nephrotoxic injury to renal tubular epithelial cells, which results in tubular dysfunction or detachment from the basement membrane. (bmj.com)
Acute tubular necrosis (ATN) is an intrinsic AKI that follows a condition of severe and persistent hypoperfusion or toxic injury of epithelial cells causing detachment of the basement membrane and tubular dysfunction. (bmj.com)
Cystatin C is well recognised marker of kidney filtration dysfunction and injury. (randox.com)

Histopathology: Toxic ATN is characterized by proximal tubular epithelium necrosis (no nuclei, intense eosinophilic homogeneous cytoplasm, but preserved shape) due to a toxic substance (poisons, organic solvents, drugs, heavy metals). (wikipedia.org)
Basement membrane is intact,[citation needed] so the tubular epithelium regeneration is possible. (wikipedia.org)
In response to acute injury, the adult kidney shows some level of regeneration characterized by the proliferation of the surviving cells and the replacement of the necrotic tubular cells with functional tubular epithelium [ 3 ]. (biomedcentral.com)

The term ATN is actually a misnomer, as there is minimal cell necrosis and the damage is not limited to tubules. (medscape.com)

Quickly treating any condition that reduces the volume or force of blood flow through the kidneys may help prevent prerenal azotemia. (medlineplus.gov)

Incidence and outcomes in acute kidney injury: a comprehensive population-based study. (bmj.com)

Infections such as acute pyelonephritis or septicemia. (health.am)

Common causes are low blood flow to the kidneys (such as caused by low blood pressure), medications that damage the kidneys, and severe bodywide infections. (msdmanuals.com)

A prerequisite for the use of these biocompatible nanoparticles in oncology daily practice is to check in vivo their tolerance in the long-term and on the organs that are the most sensitive to efficient anticancer drugs, particularly the liver, bone marrow, kidney, heart and lung [ 7 , 8 ]. (springer.com)

Injury to the kidney tubule cells harms the ability of the kidneys to filter the blood. (msdmanuals.com)

Medications that commonly damage the kidneys include aminoglycoside antibiotics (such as gentamicin and tobramycin ), amphotericin B (a medication used to treat severe, bodywide fungal infections), colistimethate (an antibiotic used to treat infections that develop in people hospitalized for another disorder), vancomycin (an antibiotic used to treat infections that are resistant to other antibiotics), and nonsteroidal anti-inflammatory drugs (NSAIDs). (msdmanuals.com)
In the most severe instances of AKI, dialysis may be warranted to compensate for the diminished kidney function 5 . (randox.com)
Metabolites of ethylene glycol produce severe metabolic acidosis and damage to the brain, heart, and kidneys. (cdc.gov)
In severe and prolonged cases, the entire kidney may become. (merckmanuals.com)
Severe acute nephritic syndrome. (health.am)
Our results revealed that iPSC-derived RPCs can protect AKI rat from renal function impairment and severe tubular injury by up-regulating the renal tubules formation, promoting cell proliferation, reducing apoptosis, and regulating the microenvironment in the injured kidney. (biomedcentral.com)

The initiation phase is characterized by an acute decrease in glomerular filtration rate (GFR), with a corresponding sudden increase in serum creatinine (Cr) and blood urea nitrogen (BUN) concentrations. (medscape.com)

Therapeutic mainstays are prevention, avoidance of further kidney damage, treatment of underlying conditions, and aggressive treatment of complications (see Treatment and Medication ). (medscape.com)
Les paramètres cliniques et obstétricales, la prise en charge, les complications et l'évolution maternelle ont été les paramètres étudiés. (bvsalud.org)

The Acute Dialysis Quality Initiative (ADQI) group first proposed the RIFLE diagnostic criteria in 2004. (hindawi.com)

Acute tubular necrosis (ATN) is a medical condition involving the death of tubular epithelial cells that form the renal tubules of the kidneys. (wikipedia.org)
Acute tubular necrosis (ATN) is a type of acute kidney injury (AKI) that results in the sudden and rapid death of tubular cells in the kidneys. (osmosis.org)

Abdominal surgery is probably associated with more likelihood to cause acute kidney injury (AKI). (biomedcentral.com)

At the kidney level, this means a loss in the glomerular filtration rate. (weber.edu)
The loss of kidney function is the result of a sudden reduction in glomerular filtration rate (GFR), the process through which waste is extracted from the blood and is often reversible 2 . (randox.com)

Objective We aimed to investigate whether preoperative serum neutrophil gelatinase-associated lipocalin (sNGAL pre-op ) predicted postoperative acute kidney injury (AKI) during hospitalisation and 1-year cardiovascular and all-cause mortality following adult cardiac surgery. (bmj.com)
Mycophenolate mofetil has also been shown to reverse ongoing acute rejection in the canine renal and rat cardiac allograft models. (nih.gov)

Traditionally, cell death has been divided into apoptosis and necrosis. (nature.com)
Recent studies have shown that in addition to necrosis and apoptosis, there are also other new programmed death modes, such as autophagy, necrosis and necrotic apoptosis, which have unique biological processes and pathophysiological characteristics. (nature.com)
It does not have the morphological characteristics of typical necrosis, such as swelling of the cytoplasm and organelles and rupture of the cell membrane, nor does it have the characteristics of traditional cell apoptosis, such as cell shrinkage, chromatin condensation, formation of apoptotic bodies and disintegration of the cytoskeleton. (nature.com)
The transplantation of iPSC-derived RPCs decreased the levels of biomarkers indicative of renal injury and attenuated the necrosis and apoptosis of renal tissues, but resulted in the up-regulation of renal tubules formation, cell proliferation, and the expression of pro-renal factors. (biomedcentral.com)

KDIGO Clinical Practice Guideline for Acute Kidney Injury. (bswhealth.com)
Identifying new markers of kidney injury with clinical value has also become an increasing focus of research. (hindawi.com)
Clinical features are those of acute kidney injury from any cause. (logicalimages.com)
KDOQI US commentary on the 2012 KDIGO clinical practice guideline for acute kidney injury. (bmj.com)

Photomicrograph of a kidney biopsy specimen shows renal medulla, which is composed mainly of renal tubules. (medscape.com)

Persistent hypoperfusion injures tubular cells in the straight portion of the proximal tubules and the thick ascending limb of the loop of Henle, especially as it dips into the relatively hypoxic medulla. (medscape.com)
The tubular epithelial cells of the S3 segment of the proximal tubule in the outer stripe of the medulla, at the corticomedullary junction, are most susceptible to ischemic injury as these cells live in a relatively hypoxic environment. (medscape.com)
80-100 μg/dL) disrupts both proximal tubular structure and function. (medscape.com)
Lead is absorbed by the proximal tubular cells of the renal tubules, where it binds to specific lead-binding proteins. (medscape.com)
10 ] showed that the transplantation of mouse ESCs-derived RPCs can result in the stable integration into proximal tubules with normal morphology and normal polarization injection into developing live newborn mouse kidneys, suggesting the potential of ESCs for application in regenerative therapies. (biomedcentral.com)

Toxic ATN occurs when the tubular cells are exposed to a toxic substance (nephrotoxic ATN). (wikipedia.org)
but it can also be due to exposure to toxins and nephrotoxic drugs which cause damage to the tubular cells. (osmosis.org)

Overview of Kidney Filtering Disorders Each kidney contains about 1 million filtering units (glomeruli). (msdmanuals.com)
Accurately document acute kidney disorders. (bswhealth.com)

This is a photomicrograph of a kidney tissue sample, which had been extracted from a patient with an acute case of cholera. (cdc.gov)

Pathophysiology and etiology of acute kidney injury. (medlineplus.gov)

Acute kidney injury and mortality in hospitalized patients. (bmj.com)

While tubular and glomerular functions generally remain intact, pre-renal AKI may be caused by systemic hypoperfusion (decreased blood flow) or selective hypoperfusion to the kidney, caused by renal artery stenosis or aortic dissection 3 . (randox.com)

Microscopically, diffuse hepatic necrosis with biliary hyperplasia is seen. (dvm360.com)

The number of Kidney transplants has increased in last decades for many advances in diagnostic and therapeutic reasons. (intechopen.com)

Obstruction affecting one side might not invariably lead to acute kidney injury, especially when the impediment develops slowly, such as with tumour growth. (randox.com)

Acute tubulointerstitial nephritis (ATIN) involves an inflammatory infiltrate and edema affecting the renal interstitium that often develops over days to months. (merckmanuals.com)

CT scan findings of patients with acute tubular necrosis may include alterations in kidney size, striate nephrogram, accumulation of fluid around kidneys . (wikidoc.org)
Cette étude a permis de déterminer la fréquence et l'étiologie de l'insuffisance rénale aiguë chez des patients hospitalisés en Arabie saoudite sur une période de 2 ans. (who.int)
Through prospective enrollment of canine patients at the Ross University Veterinary Clinic, on St. Kitts, four cases of acute fatal leptospirosis were diagnosed. (mdpi.com)
Predicting one-year mortality of critically ill patients with early acute kidney injury: data from the prospective multicenter FINNAKI study. (bmj.com)
Acute kidney injury (AKI) occurs in up to 20% of patients admitted to hospital and results in significant morbidity and mortality [ 1 ]. (karger.com)
Among these patients, only 26 (22%) had features suggestive of acute tubular necrosis (ATN). (biomedcentral.com)
98 patients (41 female, mean age 66.4 ± 13.9 years) who underwent acute RRT according to local indications for post-major abdominal surgery AKI between 1 January, 2002 and 31 December, 2005 were enrolled The demographic data, comorbid diseases, types of surgery and RRT, as well as the indications for RRT were documented. (biomedcentral.com)
The findings of this study support earlier initiation of acute RRT, and also underscore the importance of predicting prognoses of major abdominal surgical patients with AKI by using RIFLE classification. (biomedcentral.com)

Causes of obstruction include kidney stones, tumours, or blood clots, commonly in the bladder outlet. (randox.com)

Anatomy8

Diseases14

Chemicals and Drugs6

Analytical, Diagnostic and Therapeutic Techniques and Equipment5

Phenomena and Processes3

Information Science1

Interstitial5

Nephropathy3

Sepsis5

Determining acute kidney1

Cortical1

Urine11

Chronic11

Hypertension4

Disease20

Fibrosis2

Ischemia6

Urinary2

Failure34

Symptoms3

Dysfunction4

Epithelium3

Cell necrosis1

Azotemia1

Incidence1

Pyelonephritis1

Blood flow to the kidneys1

Liver1

Ability of the kidneys1

Severe6

Corresponding sudden1

Complications2

Dialysis1

Death of tubular2

Cause acute kidney1

Glomerular filt2

Cardiac2

Apoptosis4

Clinical4

Biopsy1

Proximal5

Nephrotoxic2

Disorders2

Photomicrograph1

Etiology1

Injury and mortality1

Hypoperfusion1

Hepatic1

Transplants1

Lead to acute1

Inflammatory infiltrate1

Patients8

Obstruction1