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  • primary
  • When last I interacted with them 2 years ago, their labs were doing primary keratinocyte cultures from human newborn foreskins on a weekly basis. (bio.net)
  • cgb at biomail.ucsd.edu (Cindy Gustafson-Brown) wrote: I am interested in generating primary keratinocyte cell cultures and would appreciate any advice, references, protocols, and sources of reagents. (bio.net)
  • Thus, HaCaT and derived cell lines provide readily available cell culture models and might offer useful alternatives to primary or low-passaged normal keratinocytes. (springer.com)
  • Bacterial ghosts (BGs) as non-living bacterial envelopes devoid of cytoplasmic content with preserved and intact inner and outer membrane structures of their living counterparts have been used to study the ability of their surface components for the induction of antimicrobial peptides and pro-inflammatory cytokines in human primary keratinocytes (KCs). (nih.gov)
  • The primary function of keratinocytes is the formation of a barrier against environmental damage by pathogenic bacteria, fungi, parasites, viruses, heat, UV radiation and water loss. (wikipedia.org)
  • protein
  • Baden HP, Kubilus J, Wolman SR, Steinberg ML, Phillips SB, Kvedar JC (1987) The NM 1 keratinocyte line is cytogenetically and biologically stable and exhibits a unique structural protein. (springer.com)
  • Mouse keratinocyte-derived cytokine (KC) is the homolog of the human chemokine (C-X-C motif) ligand 1 (CXCL1) protein, a small cytokine belonging to the CXC chemokine subfamily. (clontech.com)
  • and 18366A) are affinity-purified IgG antibodies that recognize mouse keratinocyte chemoattractant (KC) or C-X-C motif chemokine 1 (CXCL1) protein. (clontech.com)
  • Journal
  • Susanne Brodesser and Thomas Kolter, "Dihydroceramide Desaturase Inhibition by a Cyclopropanated Dihydroceramide Analog in Cultured Keratinocytes," Journal of Lipids , vol. 2011, Article ID 724015, 9 pages, 2011. (hindawi.com)
  • growth factor
  • KC was originally identified by overexpression in murine keratinocytes, monocytes, and macrophages following stimulation by platelet-derived growth factor (PDGF) and macrophage colony-stimulating factor (M-CSF). (clontech.com)
  • either
  • Keratinocytes grown in culture were either shamirradiated or exposed to increasing doses of UVB (1-5 mJ/cm 2 ). (aacrjournals.org)
  • Inhibition of CDase using either a CDase inhibitor, N-oleoylethanolamine, or small interfering RNA (siRNA) (either to a- and/or n-CDase(s)) sensitized keratinocytes to L-UVB-induced apoptosis in parallel with further Cer accumulation. (biomedsearch.com)
  • surface
  • Collagen XVII is constitutively shed from the keratinocyte surface within NC16A domain by TACE (TNF-Alpha Converting Enzyme), metalloproteinase of the ADAM family. (wikipedia.org)