• comparative
  • It detects genomic copy number variations at a higher resolution level than conventional karyotyping or chromosome-based comparative genomic hybridization (CGH). (wikipedia.org)
  • Recently, platforms for generating high-resolution karyotypes in silico from disrupted DNA have emerged, such as array comparative genomic hybridization (arrayCGH) and SNP arrays. (wikipedia.org)
  • Thus a record of the history of karyotype changes that have occurred during evolution have been attained through comparative chromosome maps. (wikipedia.org)
  • cells
  • Historically, karyotypes have been obtained by staining cells after they have been chemically arrested during cell division. (wikipedia.org)
  • Karyotypes have been used for several decades to identify chromosomal abnormalities in both germline and cancer cells. (wikipedia.org)
  • Despite the diversity of platforms, ultimately they all use genomic DNA from disrupted cells to recreate a high resolution karyotype in silico. (wikipedia.org)
  • Media
  • Peripheral Blood Karyotyping media are ready to use, fully supplemented, RPMI-based, optimized for the short term culture of peripheral blood lymphocytes. (bioind.com)
  • samples
  • Virtual karyotypes can be performed on germline samples for constitutional disorders, and clinical testing is available from dozens of CLIA certified laboratories (genetests.org). (wikipedia.org)
  • However
  • However, like karyotyping, it may also detect abnormalities that do not have any clinical significance, which would warrant counseling of the patient to remove any unwanted anxiety. (medindia.net)