• Among them, kanamycin A is the raw material for the synthesis of amikacin sulfate and kanamycin monosulfate. (ballyabio.com)
  • Because sensitive bacteria are susceptible to kanamycin resistance, kanamycin is no longer directly used in the clinical market, but after deep addition, it produces kanamycin monosulfate, amikacin sulfate and other products for clinical use. (ballyabio.com)
  • The second-line injectable drugs are amikacin, kanamycin, and capreomycin. (cdc.gov)
  • Extensively drug resistant-tuberculosis is defined as multidrug-resistant tuberculosis that is also resistant to any one of the fluoroquinolones and to at least one of three injectable second-line antibiotics (amikacin, capreomycin or kanamycin). (who.int)
  • MDR-TB that is also resistant to any one of the fluoroquinolones and to at least one of three injectable second-line medicines (amikacin, capreomycin or kanamycin).6 MDR-TB and XDR-TB are principally a result of inadequate or poorly administered treatment regimens. (who.int)
  • This enzyme is also called neomycin-kanamycin phosphotransferase. (wikipedia.org)
  • Kanamycin sulfate can be used as a selection agent for bacteria transformed with the kanamycin B resistance gene and transformants carrying the neomycin phosphotransferase (NptII/neo) gene. (yeasen.com)
  • capreomycin, or kanamycin. (cdc.gov)
  • Kanamycin Sulfate Solution is a 10 mg/mL broad-spectrum aminoglycoside antibiotic solution used as a supplement to cell culture media to control bacterial contamination. (bioind.com)
  • Kanamycin sulfate is an aminoglycoside antibiotic. (ballyabio.com)
  • Kanamycin Sulfate, an aminoglycoside antibiotic effective against Gram-negative bacteria, Gram-positive bacteria, and mycoplasma, inhibits translocation and protein synthesis by binding to the 70S ribosomal subunit. (plantmedia.com)
  • Kanamycin Acid Sulfate, BP is an aminoglycoside antibiotic often used to select for bacteria which have been successfully transformed with a plasmid conferring kanamycin resistance. (toku-e.com)
  • It is used for the infection of Staphylococcus, Pneumococcus, Proteus, Pseudomonas aeruginosa and Escherichia coli, and also for the infection of Gram-negative bacteria resistant to kanamycin and gentamicin. (ballyabio.com)
  • Kanamycin sulfate, also known as Kanamycin sulfate or Kanamycin A, is an aminoglycoside bacteriocidal antibiotic and can be used as a selection agent for bacteria. (yeasen.com)
  • Kanamycin sulfate is an aminoglycoside bacteriocidal antibiotic and is effective against gram-negative and gram-positive bacteria, and mycoplasma. (yeasen.com)
  • If the bacteria produces an enzyme that destroys kanamycin, it can become a resistant strain. (ballyabio.com)
  • Kanamycin-resistant plasmids are often used as selection genes or marker genes for molecular cloning. (ballyabio.com)
  • Kanamycin Acid Sulfate is commonly used as a selective agent to select for resistant mammalian, fungal, or bacterial cells that contain the kanMX marker or other Kanamycin resistance genes. (toku-e.com)
  • Applications: For use with Kanamycin resistant stains and stains harboring plasmids such as pPIC9K, pCRBlunt, pUC9P series plasmids. (crystalgen.com)
  • Kanamycin Acid Sulfate is typically used at a concentration of 50 µg/mL. (toku-e.com)
  • Under the optimal experimental conditions, the concentration of kanamycin was proportional to the degree of ECL quenching within a linear range of 5-4500 × 10-12 mol L-1 at 0.8 V (vs. Ag/AgCl electrode electrode ), and the detection limit was 5.8 × 10-13 mol L-1. (bvsalud.org)
  • Kanamycin sulfate inhibits translocation and elicits miscoding by binding to the 70S ribosomal subunit. (yeasen.com)
  • In the current kanamycin extraction process, in the final crystallization process, ethanol is added to the concentrate and then crystallized and then centrifuged. (ballyabio.com)
  • In addition to ethanol, there is a small amount of kanamycin A in the resulting crystal mother liquor. (ballyabio.com)
  • With the kanamycin B component, ethanol can be reused after recovery. (ballyabio.com)
  • Kanamycin is very soluble in aqueous solution at 92.3 mg/mL. (toku-e.com)
  • Aminoglycoside-3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an enzyme that primarily catalyzes the addition of phosphate from ATP to the 3'-hydroxyl group of a 4,6-disubstituted aminoglycoside, such as kanamycin. (wikipedia.org)
  • The systematic name of this enzyme class is ATP:kanamycin 3'-O-phosphotransferase. (wikipedia.org)
  • Kanamycin injection is used to treat serious bacterial infections in many different parts of the body. (drugs.com)
  • Kanamycin injection is usually used for serious bacterial infections for which other medicines may not work. (drugs.com)
  • Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of kanamycin injection in children. (drugs.com)
  • No information is available on the relationship of age to the effects of kanamycin injection in geriatric patients. (drugs.com)
  • However, elderly patients are more likely to have kidney problems, which may require caution and an adjustment in the dose for patients receiving kanamycin injection. (drugs.com)
  • Kanamycin can be used for oral and intravenous injections, and is effective against a variety of bacterial infections. (ballyabio.com)
  • For the treatment of bacterial infections due to kanamycin sensitive organisms in dogs and cats. (fda.gov)
  • A common cause of resistance to kanamycin (KAN) in tuberculosis is overexpression of the enhanced intracellular survival (Eis) protein. (uky.edu)
  • OMC/In2O3 effectively amplified the ECL signal of the C-dots, thereby enhancing the detection sensitivity , whereas kanamycin quenched the signal. (bvsalud.org)
  • Used as a selection agent for cells transformed with kanamycin B (neoR, kanR) resistance gene. (thomassci.com)
  • Each milliliter of solution contains 50 or 200 milligrams (mg) of kanamycin as kanamycin sulfate. (fda.gov)
  • Kanamycin is a protein biosynthesis inhibitor that binds to 30S ribosomes to cause miscoding of the mRNA code and inhibit bacterial protein synthesis. (ballyabio.com)
  • Thermo Scientific™ Remel Kanamycin Disc is used for presumptive identification of anaerobic gram-negative bacilli, including Bacteroides fragilis. (gssl.net)
  • Kanamycin Test is based on the Colloidal Gold Immunochromatography to detect the Kanamycin residues in honey products. (ballyabio.com)
  • High purity EvoPure ® kanamycin products can be used to analyze the specific effects of individual kanamycin fractions. (toku-e.com)
  • Kanamycin belongs to the class of medicines known as aminoglycoside antibiotics. (drugs.com)
  • Kanamycin is often used in the Agrobacterium mediated transformation while using the npt II gene as selection marker. (toku-e.com)
  • A highly sensitive kanamycin electrochemiluminescence (ECL) switch sensor was constructed. (bvsalud.org)
  • Standard grade Kanamycin is composed of a mixture of three different fractions: Kanamycin A, B, and C. Kanamycin A is the major component of the complex, and Kanamycin B (II) and C (III) are minor components. (toku-e.com)
  • Anesthesia Central , anesth.unboundmedicine.com/anesthesia/view/Davis-Drug-Guide/109063/7/kanamycin. (unboundmedicine.com)
  • After kanamycin elution, the prepared sensor retained specific kanamycin recognition sites. (bvsalud.org)