• acyl
  • Lossen rearrangement, the conversion of a hydroxamic acid to an isocyanate via the formation of an O-acyl, sulfonyl, or phosphoryl intermediate. (wikipedia.org)
  • foams
  • Organic isocyanates are used extensively in the preparation of urethane foams, coatings, and fibers, as well as in the preparation of insecticides, pesticides and the like. (google.com)
  • Isocyanates react with water to form carbon dioxide: RNCO + H2O → RNH2 + CO2 This reaction is exploited in tandem with the production of polyurethane to give polyurethane foams. (wikipedia.org)
  • Polypropylene polybenzyl isocyanate, or PPI, is a polyurea-based polymer derived from isocyanate monomers that is used in some glues, aerosol foams, plastics, paint and household products. (wikipedia.org)
  • amine
  • Isocyanates also react with amines to give ureas: R2NH + R'NCO → R2NC(O)N(H)R' The addition of an isocyanate to a urea gives a biuret: R2NC(O)N(H)R' + R"NCO → R2NC(O)NR'C(O)NHR" Reaction between a di-isocyanate and a compound containing two or more amine groups, produces long polymer chains known as polyureas. (wikipedia.org)
  • exposure
  • For example, MDI is used in industrial resin flooring but the low vapour pressure of the MDI used results in very little airborne isocyanate and hence carries little risk of inhalation, although there is significant potential for dermal exposure. (seton.co.uk)
  • Other adverse health effects linked to isocyanate exposure include cancer. (seton.co.uk)
  • In particular, various studies have noted an increased lung cancer risk among workers in the polyurethane foam manufacturing industry but the association is not altogether clear, with the researchers in a 2004 study concluding they were unable to link employment with isocyanate exposure to lung cancer risk. (seton.co.uk)
  • In September 2015, the HSE published research (RR1064) on the exposure of workers to isocyanates contained in vehicle spray paints in the motor vehicle repair trade, and warned workers not to lift the protective visors of their air-fed respiratory protective equipment (RPE). (seton.co.uk)
  • The HSE says that exposure to isocyanates contained in vehicle spray paints has been the biggest cause of occupational asthma in the UK for more than a decade. (seton.co.uk)
  • The research report pointed out that, although air-fed visors (AFVs) are used within the motor vehicle repair trade for protection against exposure to isocyanate paints, it is common practice for paint sprayers to flip up the visor immediately after spraying, while still within the paint spraying area, in order to closely examine and check the quality of the paintwork. (seton.co.uk)
  • Risk of isocyanate exposure in the construction industry" (PDF). (wikipedia.org)
  • irritants
  • Isocyanates are powerful irritants to the mucous membranes of the eyes and gastrointestinal and respiratory tracts. (webwire.com)
  • Isocyanates are potentially dangerous irritants to the eyes and respiratory tract, despite their relatively low acute toxicities. (wikipedia.org)
  • Chemical
  • The EU-OSHA has noted in an expert forecast on emerging health and safety risks that the increasing use of isocyanates justifies its inclusion in a list of emerging chemical risks. (seton.co.uk)
  • The Occupational Safety and Health Administration (OSHA) reports that isocyanates are one of the most common chemical causes of work-related asthma. (webwire.com)
  • The structure of CSI is represented as ClS(O)2-N=C=O. It consists of two electron-withdrawing components, the chlorosulfonyl group (SO2Cl) and the isocyanate group (-N=C=O). Because of its resulting electrophilicity, the use of CSI in chemical synthesis requires relatively inert solvents such as chlorocarbons, acetonitrile, and ethers. (wikipedia.org)
  • amines
  • Isocyanates are common intermediates in the synthesis of primary amines via hydrolysis: Hofmann rearrangement, a reaction in which a primary amide is treated with a strong oxidizer such as sodium hypobromite or lead tetraacetate to form an isocyanate intermediate. (wikipedia.org)
  • Characteristic of other isocyanates, it reacts with amines to give ureas. (wikipedia.org)
  • OSHA
  • The European Agency for Safety and Health at Work (EU-OSHA) recently highlighted isocyanates as a new and emerging risk, amid concerns that workers have not always been as well protected from these widely used substances as they should. (seton.co.uk)
  • poisonous
  • Methacryloyloxyethyl isocyanate is an extremely poisonous liquid which can be fatal if inhaled, absorbed through skin, or consumed orally. (wikipedia.org)
  • novel
  • Novel thioether isocyanates and isothiocyanates are produced by the addition of thiols to the olefinic bonds of allyl isocyanates and isothiocyanates. (patentgenius.com)
  • More particularly, this invention relates to the free radical type thiol adducts of allyl isocyanate and isothiocyanate, i.e., 3-substituted thiopropyl isocyanates andisothiocyanates as novel compositions having unexpected properties. (patentgenius.com)
  • hydrogen
  • Since the reaction whereby the isocyanate group is blocked is a reversible one, it would be expected that by using a more volatile material, the blocking agent would be more easily removed from the system and the iso cyanate group could then be reacted with a material hav ing an active hydrogen. (google.com.au)
  • It was believed that if the blocking agents were not removed, then the blocking agents would compete with the material having an active hydrogen for reaction with the free isocyanate groups. (google.com.au)
  • Therefore, volatile materials were generally used as blocking agents both to assure that the blocking agent would not compete with the material containing any active hydrogen for the free isocyanate groups, and to assure a taster release time. (google.com.au)
  • NSF3 reacts with carbonyl fluoride (COF2) in the presence of hydrogen fluoride to form pentafluorosulfanyl isocyanate (SF5NCO). (wikipedia.org)
  • temperature
  • Although, phenol is a satisfactory blocking agent for isocyanates, the use of temperatures of about 160 C. in releasing the isocyanate group from its blocked condition results in an economic disadvantage in the cost of creating and maintaining such a high temperature. (google.com.au)
  • Therefore, the temperature needed to release the blocked isocyanate group is an important consideration in selecting the blocking agent. (google.com.au)