• currents
  • Sustained currents through ASIC3 ion channels at the modest pH changes that occur during myocardial ischemia. (semanticscholar.org)
  • Other inwardly rectifying channels, termed "strong inward rectifiers," carry very little outward current at all, and are mainly active at voltages negative to the K+ reversal potential, where they carry inward current (the much larger currents below the 0 nA line in figure 1). (wikipedia.org)
  • occur
  • Each subunit binds ions independently of the other, meaning conduction or exchange occur independently in each subunit. (wikipedia.org)
  • Role
  • The role of HCN channels in autonomic control of heart rate is currently a matter of ongoing investigation. (wikipedia.org)
  • Inward rectifiers play a role in setting cellular membrane potentials, and closing of these channels upon depolarization permits the occurrence of long duration action potentials with a plateau phase. (wikipedia.org)