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  • bases
  • CHOP consists of: (C)yclophosphamide, an alkylating agent which damages DNA by binding to it and causing the formation of cross-links (H)ydroxydaunorubicin (also called doxorubicin or adriamycin), an intercalating agent which damages DNA by inserting itself between DNA bases (O)ncovin (vincristine), which prevents cells from duplicating by binding to the protein tubulin (P)rednisone or (P)rednisolone, which are corticosteroids. (wikipedia.org)
  • vivo
  • Chem-seq was tested on three classes of drugs using MM1.S multiple myeloma cells to: 1) Investigate the genome-wide binding of the bromodomain inhibitor JQ1 to the BET bromodomain family members BRD2, BRD3 and BRD4 2) Map the genomic binding sites of AT7519, an inhibitor of the cyclin dependent kinase CDK9, and 3) Study how the DNA intercalating agent psoralen interacts with genomic DNA in vivo. (wikipedia.org)
  • tumors
  • The second generation and an isosteric series of isoxazolidinyl polycyclic aromatic hydrocarbons, as DNA-intercalator agents designed to act on remotely implanted tumors, have been synthesized in good yields according to the 1,3-dipolar cycloaddition methodology. (unime.it)
  • Quantitative studies of the effects of nitrogen mustard analogs and other alkylating agents on ascites tumors in mice" Can. (patentgenius.com)
  • thus
  • Single-stranded RNA can also be detected, since it usually folds back onto itself and thus provides local base pairing for the dye to intercalate. (wikipedia.org)
  • changes
  • During agarose gel electrophoresis, plasmid pBR322 the drug-free DNA is negatively supercoiled and migrates through the gel as a single band, but its profile changes significantly in the presence of an intercalating agent (EtBr). (thefreedictionary.com)
  • bases
  • CHOP consists of: (C)yclophosphamide, an alkylating agent which damages DNA by binding to it and causing the formation of cross-links (H)ydroxydaunorubicin (also called doxorubicin or adriamycin), an intercalating agent which damages DNA by inserting itself between DNA bases (O)ncovin (vincristine), which prevents cells from duplicating by binding to the protein tubulin (P)rednisone or (P)rednisolone, which are corticosteroids. (wikipedia.org)
  • vivo
  • Chem-seq was tested on three classes of drugs using MM1.S multiple myeloma cells to: 1) Investigate the genome-wide binding of the bromodomain inhibitor JQ1 to the BET bromodomain family members BRD2, BRD3 and BRD4 2) Map the genomic binding sites of AT7519, an inhibitor of the cyclin dependent kinase CDK9, and 3) Study how the DNA intercalating agent psoralen interacts with genomic DNA in vivo. (wikipedia.org)
  • tumors
  • The second generation and an isosteric series of isoxazolidinyl polycyclic aromatic hydrocarbons, as DNA-intercalator agents designed to act on remotely implanted tumors, have been synthesized in good yields according to the 1,3-dipolar cycloaddition methodology. (unime.it)
  • Quantitative studies of the effects of nitrogen mustard analogs and other alkylating agents on ascites tumors in mice" Can. (patentgenius.com)
  • thus
  • Single-stranded RNA can also be detected, since it usually folds back onto itself and thus provides local base pairing for the dye to intercalate. (wikipedia.org)
  • changes
  • During agarose gel electrophoresis, plasmid pBR322 the drug-free DNA is negatively supercoiled and migrates through the gel as a single band, but its profile changes significantly in the presence of an intercalating agent (EtBr). (thefreedictionary.com)