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  • hormone
  • Biochemical growth hormone deficiency is prevalent among human immunodeficiency virus-infected patients, but if this condition is clinically relevant remains challenging. (unimore.it)
  • The aim is to prospectively compare the growth hormone deficiency/insulin-like growth factor-1 status of 71 human immunodeficiency virus-infected patients with impaired growth hormone response to growth hormone releasing hormone + Arginine with that of 65 hypopituitary patients affected by a true growth hormone deficiency secondary to pituitary disease. (unimore.it)
  • In all the patients total body fat was associated with both growth hormone peak and area under the curve at stepwise linear regression analysis. (unimore.it)
  • The degree of growth hormone deficiency is more severe in hypopituitary than in human immunodeficiency virus-infected patients, suggesting that the function of growth hormone/insulin-like growth factor-1 axis is partially rescued in the latter thanks to a preserved pituitary secretory reserve. (unimore.it)
  • However, while the growth promoting potential of pGH therapy is unequivecol, the modes of action of the hormone remain unclear, and there is only limited information as to how the animals responsiveness to this technology might be modified by factors such as sex, genotype or nutrient intake. (livestocklibrary.com.au)
  • hepatic
  • Adipose-specific disruption of mTORC2 through deletion of Rictor may protect from a high-fat diet in young mice, but results in hepatic steatosis and insulin resistance in older mice. (wikipedia.org)
  • deficiency
  • These agents improve symptoms associated with growth hormone deficiency (GHD). (medscape.com)
  • Dose-dependent effect of growth hormone on final height in children with short stature without growth hormone deficiency. (medscape.com)
  • Lindsay R, Feldkamp M, Harris D, Robertson J, Rallison M. Utah Growth Study: growth standards and the prevalence of growth hormone deficiency. (medscape.com)
  • Accordingly, research has found that girls with growth hormone deficiency (GHD) who are treated with GH experience accelerated breast growth and that boys with GHD treated with GH sometimes experience gynecomastia. (wikipedia.org)
  • There are an estimated 30 people in the world that have been diagnosed with the congenital form of Factor II deficiency, which should not be confused with the prothrombin G20210A mutation, which is also called the factor II mutation. (wikipedia.org)
  • short stature
  • The measurement of IGF-1 in conjunction with growth hormone assessment can also be used in the investigation of short stature to establish the cause of retarded growth. (news-medical.net)
  • Consensus statement on the diagnosis and treatment of children with idiopathic short stature: a summary of the Growth Hormone Research Society, the Lawson Wilkins Pediatric Endocrine Society, and the European Society for Paediatric Endocrinology Workshop. (medscape.com)
  • Effect of growth hormone treatment on adult height in peripubertal children with idiopathic short stature: a randomized, double-blind, placebo-controlled trial. (medscape.com)
  • tissues
  • IGF-I is essential for normal growth of children's bones, cartilage, and organs by stimulating uptake of glucose, fatty acids, and amino acids into tissues. (medscape.com)
  • levels
  • They participate in the growth and function of almost every organ in the body, and are also partially capable of reducing blood glucose levels. (news-medical.net)
  • IGF-1 is one of the body's most important growth promoters during infancy and childhood, but later in life, elevated IGF-1 levels accelerate the aging process, p. (drfuhrman.com)
  • placental
  • It has been found to be embedded in the first exon of the large intergenic non-coding RNA H19, which is responsible for limiting placental growth prior to birth. (wikipedia.org)
  • human
  • Karey, K.P., and Sirbasku, D.A., Differential responsiveness of human breast cancer cell lines MCF-7 and T47D to growth factors and 17b-estradiol. (sigmaaldrich.com)
  • The Insulin-Like Growth Factor System in the Human Pathology, Hot Topics in Endocrine and Endocrine-Related Diseases Monica Fedele, IntechOpen, DOI: 10.5772/55213. (intechopen.com)
  • Ribosomal scanning on human insulin-like growth factor II (IGF-II) is hard to comprehend due to one open reading frame and the ability for the hormone to fold into a stable structure. (wikipedia.org)
  • Capacity
  • Phosphorylation of eukaryotic initiation factor 4e (eif-4E) [4EBP] by mTOR inhibits the capacity of 4EBP to inhibit eif-4E and slow metabolism. (wikipedia.org)