• The drugs primarily used for intralesional injections are corticosteroids. (ashwinisdermacare.com)
  • ATROPHY is a well-documented dosage-dependent aspect effect of the injection of repository corticosteroids into skin.1,2 Nonetheless, like certain noxious by-products of chemical manufacture, uncomfortable side effects of medication in the distinctive circumstance may have their own advantage and be intentionally sought after. (page.tl)
  • Treatment of subglottic stenosis, due to Wegener's granulomatosis, with intralesional corticosteroids and dilation. (nih.gov)
  • Patients diagnosed with either alopecia totalis or alopecia universalis were significantly less likely to receive intralesional steroids and significantly more likely to receive topical corticosteroids than those without these diagnoses (11.1% vs 44.1% and 25.4% vs 42.1, respectively). (medscape.com)
  • Topical or intralesional corticosteroids are most commonly used for treatment of LSC. (jcadonline.com)
  • Regardless of its advantages, intralesional steroid injections could trigger a number of opposed unintended effects, each local, such as telangiectasias, skin and subcutaneous fats atrophy, pigmentary adjustments (hypopigmentation and hyperpigmentation), skin necrosis and ulcerations, and systemic results, such as Cushing's syndrome. (page.tl)
  • The goal of intralesional therapy is to treat local tissues with a minimum number of systemic side effects by delivering a medicine directly into a specific skin lesion. (cosmiquecochin.com)
  • The combination of intralesional PV-10 with the systemic administration of gemcitabine delayed the growth treated tumors and non-injected distal tumors. (bmj.com)
  • Objective: To determine if psoriasis plaques will respond to intralesional alefacept and if this predicts a systemic response to intramuscular (IM) alefacept. (uthscsa.edu)
  • Periocular hemangioma of childhood has been treated with surgery, laser-surgery, radiation, and drugs (intralesional steroids and systemic beta-blockers). (eyecancer.com)
  • OncoVEXGM-CSF , now called T-VEC (Talimogene laherparepvec), is Amgen 's entry in the intralesional sweepstakes and is an investigational oncolytic immunotherapy designed to selectively replicate in tumor tissue and to initiate a systemic anti-tumor immune response. (drugdiscoverynews.com)
  • Intron A is supplied as a solution for intramuscular, intralesional or subcutaneous injection. (centerwatch.com)
  • The overall success rate after one course of therapy with Glucantime® was 96.5% (136/141), and all the failures (5/141) occurred with intramuscular injections. (who.int)
  • Statistical analysis showed a significant difference between the failure rates of intramuscular and intralesional injections. (who.int)
  • Always receive intralesional injections under the guidance of your dermatologist for clear, blemish-free skin. (oxygenetix.com)
  • Since its invention in 1961, intralesional injection-the percutaneous direct administration of drugs into skin lesions-has played a significant role in dermatologic therapy. (cosmiquecochin.com)
  • Objective: This case report aims to analyze the management of venous malformation therapy in the oromaxillofacial region using intralesional Bleomycin injection. (researchbib.com)
  • Conclusions Together, these results demonstrate that intralesional therapy with PV-10 can enhance the efficacy gemcitabine against pancreatic tumors. (bmj.com)
  • However, because no therapy has yet proven to be fully curative, keloid treatments have expanded to include a number of options, from injections to multimodal approaches. (springer.com)
  • Intralesional corticosteroid therapy is usually the treatment with the best response rate. (medscape.com)
  • Topical corticosteroid therapy can be useful, especially in children who cannot tolerate injections. (medscape.com)
  • Chemical peels, laser therapy, microdermabrasion, and intralesional injections are just a few examples of the remarkable procedures that can transform your complexion. (oxygenetix.com)
  • Intralesional therapy for cancer-that is, direct injection of an anti-cancer drug into the lesion-was first taken seriously back 1975. (drugdiscoverynews.com)
  • Regression of pulmonary metastatic disease associated with intralesional BCG therapy of intracutaneous melanoma metastases. (drugdiscoverynews.com)
  • When randomized trials of BCG also failed to confirm a significant clinical benefit, intralesional therapy went out of fashion. (drugdiscoverynews.com)
  • Conclusion: Treatment of this case shows that Bleomycin Intralion Injection of venous malformations is an effective non-invasive treatment and has no side effects. (researchbib.com)
  • Purpose: To compare the clinical outcomes of MSC injection and arthroscopic marrow stimulation treatment with those of arthroscopic marrow stimulation treatment alone for the treatment of OLTs in older patients. (researchgate.net)
  • Patients were divided into 2 groups: 35 patients (37 ankles) treated with arthroscopic marrow stimulation treatment alone (group A) and 30 patients (31 ankles) who underwent MSC injection along with arthroscopic marrow stimulation treatment (group B). Clinical outcomes were evaluated according to the visual analog scale (VAS) for pain, the American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Scale, and the Roles and Maudsley score. (researchgate.net)
  • These correlations were not observed in group B. Conclusion: Injection of MSCs with marrow stimulation treatment was encouraging in patients older than 50 years compared with patients treated with marrow stimulation treatment alone, especially when the lesion size was larger than 109 mm(2) or a subchondral cyst existed. (researchgate.net)
  • When possible, treatment of periocular hemangiomas of childhood involves injections of steroid into the tumor. (eyecancer.com)
  • In 1999, the U.S. FDA granted Allovectin-7 orphan drug designation for intralesional treatment of invasive and metastatic melanoma. (drugdiscoverynews.com)
  • We sought to evaluate the efficacy and safety of intradermal injection of botulinum toxin A in the treatment of localized recalcitrant chronic pruritus in lichen simplex, inverse psoriasis, post-burn itching, lichen planus (hypertrophic), and postherpetic neuralgia. (jcadonline.com)
  • After intradermal injection, efferent cholinergic innervation of sweat glands is completely blocked, making it a viable treatment option for focal hyperhidrosis. (jcadonline.com)
  • If this treatment modality is chosen, it should be followed by monthly corticosteroid injections into the treated area, or in conjunction with other intralesional injections. (spokesman-recorder.com)
  • Initially, the treatment consisted of intralesional corticosteroid injections. (bvsalud.org)
  • In this study, we explored the ability of intratumoral injections of PV-10, a 10% solution of rose bengal, to induce lesion-specific ablation and control of metastatic pancreatic tumors in a murine model. (bmj.com)
  • Two cases of primary cutaneous nocardiosis caused by intralesional injection. (medscape.com)
  • Intralesional vitamin D injections are effective and safe for treating patients with keloid scars, according to the results of a study published in the Journal of Cosmetic Dermatology, per Dermatology Advisor. (plasticsurgerypractice.com)
  • Initial studies of both bleomycin injection and topical application with penetration enhanced via multiple needle punctures showed therapeutic benefit [ 5 , 6 ]. (springer.com)
  • Scalp Ulcer due to Intralesional Corticosteroid Injection. (qxmd.com)
  • In this case, the perforation might have been caused by food impaction and delayed ulcer healing due to triamcinolone injection . (bvsalud.org)
  • Forty patients (60 hips) with stage I, II or III (ARCO system) osteonecrosis of femoral head were treated by either core decompression and isolated mononuclear cells (group A) or core decompression and unprocessed bone marrow injection (group B). The patients were followed up clinically and radiologically for a minimum of 2 years. (nih.gov)
  • Patients received weekly intralesional alefacept of increasing concentrations into target plaques for 3 weeks followed by IM injections for 12 weeks and concluded with an observation period of 9 weeks. (uthscsa.edu)
  • Use of a combination bleomycin and triamcinolone injection was found to be effective in a study of 35 keloids and two hypertrophic scars in 10 white patients. (springer.com)
  • Determine the clinical activity of this regimen, in terms of inflammation at injection site(s) and disease regression or stabilization, in these patients. (knowcancer.com)
  • Le taux de succès global après un traitement par Glucantime® était de 96,5 % (136/141), et tous les échecs (5/141) ont été observés chez les patients ayant reçu des injections intramusculaires. (who.int)
  • Case Report: A 39-year-old female patient diagnosed with simple venous malformations which carried out bleomycin injection at RSUP Dr. Hasan Sadikin Bandung. (researchbib.com)
  • After there sessions of injection, the lesion was significantly reduced from volume and size by more than 51 % but still could look at different colours (score 3). (researchbib.com)
  • On day 7, a single tumor was treated with intralesional PV-10. (bmj.com)
  • It was hypothesized that localized pruritus in LSC, if mediated by acetylcholine sensitive C-fibers, could be blocked by intradermal botulinum toxin type A injections. (jcadonline.com)
  • Compared with intra-lesional injection of meglomine antimoniate in Iran. (who.int)
  • Other common treatments include silicone sheets, compression, intralesional administration of 5-fluorouracil, and excision. (springer.com)
  • These findings suggest that MVIIC at 15, 30 and 60 pmol are safe for intralesional administration after spinal cord injury and could be further investigated in relation to its neuroprotective effects. (biomedcentral.com)
  • For those pesky acne cysts that refuse to budge, corticosteroid injections offer a targeted solution. (oxygenetix.com)
  • Each 1 mL of solution for injection contains 3.32 mg of dexamethasone (as dexamethasone sodium phosphate) which is equivalent to 4.00 mg of dexamethasone phosphate or 4.37 mg dexamethasone sodium phosphate. (who.int)
  • Each cyst is given a single injection of a dilute cortisone solution, using an ultrathin needle. (online-family-doctor.com)
  • Intralesional corticosteroid injection and dilatation provides effective management of subglottic stenosis in Wegener's granulomatosis. (nih.gov)
  • Sufferers that have specific set off factors that may be elicited with palpation (a agency contact) might expertise probably the most aid from injections. (page.tl)