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  • enzyme
  • 4. Catabolite repression When a microorganism is provided with a rapidly metabolizable carbon-energy source such as glucose, the resulting increase in the intracellular concentration of ATP leads to the repression of enzyme(s) biosynthesis, thus causing a slower metabolization of the energy source. (wikipedia.org)
  • A powerful method of overcoming the catabolite repression in the enzyme biosynthesis is a fed-batch culture in which glucose concentration in the culture liquid is kept low, where growth is restricted, and the enzyme biosynthesis is derepressed. (wikipedia.org)
  • 0.12
  • Synephrine has been found in marmalade made from Citrus unshiu (Satsuma mandarin) obtained in Japan, at a concentration of ~0.12 mg/g (or about 2.4 mg/20g serving). (wikipedia.org)
  • dose
  • The in vivo inhibitory effects of BDM-X on lipopolysaccharide (LPS)-induced thiobarbituric acid reactive substance (TBARS) and protein carbonyl formations as oxidative markers, are approximately two to three times higher than that of ABM at the same dose. (wikipedia.org)
  • The reason for using 50% endpoints is that many dose-response relationships in biology follow a logistic function that flattens out as it approaches the minimal and maximal responses, so it is easier to measure the concentration of the test substance that produces a 50% response. (wikipedia.org)
  • compounds
  • The level of specific binding of the radioligand is then determined in the presence of a range of concentrations of other competing non-radioactive compounds (usually antagonists), in order to measure the potency with which they compete for the binding of the radioligand. (wikipedia.org)
  • substance
  • This substance is present at very low concentrations in common foodstuffs such as orange juice and other orange (Citrus species) products, both of the "sweet" and "bitter" variety. (wikipedia.org)
  • METHODS
  • METHODS: A MDR human HCC cell line, SMMC-7721/ADM, was developed by exposing parental cells to gradually increasing concentrations of adriamycin. (biomedsearch.com)
  • See article above for overview of 50% endpoints and comparison with other methods of calculating 50% endpoints. (wikipedia.org)
  • times
  • Analysis of dried fruit of C. aurantium grown in Italy showed a concentration of synephrine of ~1 mg/g, with peel containing over three times more than the pulp. (wikipedia.org)
  • below
  • Horses must be sedated, because movement can force blood past the tourniquet and reduce the concentration of drug below the site of the tourniquet. (wikipedia.org)
  • Below critical micellar concentrations (CMCs) the fatty acid tail can extend freely into solution, and then participate in hydrophobic interactions within micelles. (wikipedia.org)
  • However, when ampicillin is given in combination with sulbactam, regrowth of bacteria has been seen when sulbactam levels fall below certain concentrations. (wikipedia.org)
  • The ligand is used at a low concentration, usually at or below its Kd value. (wikipedia.org)
  • allows
  • Although it is not well understood, this relationship allows for AMPT's inhibitory property, which blocks tyrosine hydroxylase, to increase dopamine transport by the vesicle monoamine transporter-2. (wikipedia.org)
  • site
  • AETX I is part of the sea anemone sodium channel inhibitory subfamily 1 and binds to the neurotoxin receptor site 3 of voltage-gated sodium channels, slowing down their inactivation. (wikipedia.org)
  • culture
  • The advantage of the fed-batch culture is that one can control concentration of fed-substrate in the culture liquid at arbitrarily desired levels (in many cases, at low levels). (wikipedia.org)
  • Generally speaking, fed-batch culture is superior to conventional batch culture when controlling concentrations of a nutrient (or nutrients) affect the yield or productivity of the desired metabolite. (wikipedia.org)
  • To cultivate the mutant on a low concentration of the required nutrient, it is fed to the batch culture at a controlled rate. (wikipedia.org)
  • species
  • As of May 2016, the family Halobacteriaceae comprises 50 genera 213 species. (wikipedia.org)
  • with inhibitory activity ranging from narrow (closely related Lactobacillus species) to broad (diverse groups of bacteria, including G. vaginalis and P. bivia), and bacteriocin-like substances, with a broader spectrum of activity than bacteriocins (e.g. a heat-resistant peptide produced by Lactobacillus salivarius subsp. (wikipedia.org)
  • overall
  • the leaves are two- to four-pinnate, finely divided and lacy, overall triangular in shape, up to 50 cm (20 in) long and 40 cm (16 in) broad. (wikipedia.org)