• Men are considered infertile if they produce too few sperm cells, sperm cells of poor quality, or have chronic problems with ejaculation. (
  • The incidence of chromosomal aberrations in population is approximately 0.6 per cent whereas infertile men have an eight to 10-fold higher frequency of chromosomal anomalies than fertile men," she said strongly recommending genetic karyotyping (chromosome analyses). (
  • Doctors say that genetics plays an important role in maintenance of normal spermatogenesis (sperm production) and in about 30 per cent of infertile males, chromosomal abnormalities and gene mutations have been associated with infertility. (
  • Prostatitis: present in 25 to 30% of infertile compared to 10-15 % of fertile men. (
  • The good news is that, without any treatment at all, about 25% of supposedly infertile men bring about a pregnancy within a year of the time they first visit a physician for treatment. (
  • In one double-blind study of 375 infertile men, supplementation with vitamin B 12 produced no benefits on average in the group as a whole. (
  • Methods: In this cross-sectional study, with 71 infertile women with diagnosis unexplained infertility and male infertility, blood samples were obtained during the proliferative and secretory phases of an arbitrary menstrual cycle. (
  • It is known that infertility is associated with active folic acid supplement use, but the effect of socioeconomic and lifestyle factors on folic acid supplement use in infertile women has not been well investigated. (

sperm count

  • Which has been shown to actually reduce a man's sperm count and lead to infertility ? (
  • Low sperm count is an uncomfortable subject for some men to discuss, which may be why so many urban legends have sprung up about its causes. (
  • Men with a low sperm count who had fathered children in the past had a lower risk of developing testicular cancer than men who had been unable to father children at all. (
  • Couples with a male partner's sperm count of less than about 5 million per cc, or the motility below about 30% will most likely need IVF with ICSI in order to conceive. (
  • Researchers also observed that the more medications a man reported taking, the higher his risk of a low sperm count. (
  • Male infertility, the inability of a man to produce a pregnancy in a woman, is often caused by measurable deficits in sperm function or sperm count. (
  • 3 However, in a particular subgroup of men with sufficiently low sperm count and sperm motility, B 12 appeared to be helpful. (
  • According to a study in Fertility and Sterility, men with fertility problems who were given a daily dose of 66 mg of zinc sulfate and 5 mg of folic acid for 6 months boosted their total sperm count by 74 percent. (


  • Different factors contribute to male infertility including various gene defects and chromosomal abnormalities," said Dr Kiran Singh, assistant professor, department of molecular and human genetics, BHU. (


  • In his own clinic at the University of Wisconsin, Williams notes, couples are screened together, with the woman seeing an OB/GYN and the man seeing a urologist. (
  • Couples are evaluated for male and female factor infertility issues simultaneously," he said. (
  • Fertility really is a couples thing not just a male or a female thing. (
  • As reported in the issue of the British Medical Journal (BMJ), the study found a strong association between men with infertility problems and the subsequent risk of testicular cancer, with men in couples with fertility problems being over 1.5 times more likely to develop testicular cancer than other men. (
  • Infertility is a condition wherein couples fail to achieve pregnancy or if the woman has been unable to carry a pregnancy that results in a live birth. (
  • A report documented by the Department of Atomic Energy (DAE) and Council for Scientific and Industrial Research (CSIR), in collaboration with the Banaras Hindu University (BHU), has strongly called for genetic screening of infertility cases in males before referring childless couples for invitro fertilisation (IVF). (
  • Infertility is a multi-factorial disorder effecting eight per cent of couples worldwide and among them about half could be traced to the male partner. (
  • These couples should consider seeing an infertility specialist for a discussion of their options. (
  • Couples considering varicocele surgery should see a well trained urologist as well as an infertility specialist for education about all of their options before proceeding. (
  • The research could open up new ways to screen and treat couples for infertility. (
  • A 2011 Cochrane review of 34 studies concluded that couples in which the male took antioxidant supplementation while the female underwent assisted reproduction were almost 5 times more likely to have a live birth than couples who didn't supplement. (

Vitro Fertilization

  • In other words, if a couple will need inseminations with male partner's sperm , or possibly in vitro fertilization anyway, why waste time, money, etc. on surgery for a varicocele. (

folic acid

  • The men with vitamin D deficiency were also found to be more likely to be deficient in folic acid - also important for male fertility - and to have higher levels of homocysteine. (


  • One of the mysteries of human fertility is that sperm quality and quantity seem to have little do with whether or not a man is fertile, said Ted Tollner, first author of the paper, who carried out the work as a postdoctoral scholar with Cherr. (
  • 22 A total of 108 fertile men and 103 men with impaired fertility ("subfertile men") participated in the study. (
  • neither supplement alone produced this effect, and there was little effect of the combined therapy on fertile men. (


  • The most common treatable cause of male factor infertility is called varicocele," said Dr. Dan Williams, director of male reproductive medicine and surgery at the University of Wisconsin School of Medicine and Public Health. (
  • In our opinion, varicocele surgery is probably not a viable option for men with such low numbers. (
  • Men with counts that are just slightly low (15-20 million) may be more reasonable candidates for varicocele surgery. (
  • The jury is still out on how effective varicocele surgery is as a treatment of male infertility. (


  • This is another reason it's very important for men to be evaluated by a urologist who's specially trained in male infertility," said Williams, noting that the common route of the man being evaluated by his primary care doctor or his partner's OB/GYN is often not enough. (


  • Vitamin D and folate deficiency are known to be associated with infertility in women, but the outcomes of the screening among men in our study group came as a complete surprise. (
  • Folate and genetic variations in folate metabolism have also been associated with infertility, but it remains unclear how these factors affect IVF pregnancy outcome. (


  • Treatment will depend on the cause of the infertility. (
  • Our data extended the role of 1,25(OH)2D3 beyond its conventional physiological actions, paving the way for novel therapeutic opportunities in the treatment of the male reproduction disorders. (
  • Scientists at the Queen's University have revealed a unique fertility treatment that could improve male infertility. (
  • In a double-blind, placebo-controlled study of 110 men whose sperm showed subnormal activity, daily treatment with 100 IU of vitamin E resulted in improved sperm activity and increased rate of pregnancy in their partners. (
  • With these results, the researchers concluded that L-carnitine supplementation is a "reasonable, safe, and effective" male infertility treatment. (
  • Various hormones have been studied as regards prediction of pregnancy outcome after infertility treatment, but no ideal candidate has been found. (
  • Liver or kidney disease, or treatment for seizure disorders are examples of problems that can cause infertility. (
  • Treatment depends on what is causing your infertility. (
  • Hormone treatment may help you if you have a hormone disorder causing your infertility. (



  • Genetic anomalies have been identified as one of main reasons for male infertility in the country. (
  • All patients with chromosomal anomalies were azoospermic (when mature sperm are not found in the semen because of sperm production failure at various stages) and they posed one or the other feature of Klinefelter syndrome, a male genetic disorder. (


  • Infertility treatments can be costly and lengthy. (


  • A study from the State University of New York at Stony Brook was published in the Journal of Urology in 1998 where 97 men with infertility were examined to see if their underwear choice made a difference. (
  • Infertility affects 10 to 15 percent of the U.S. population, said John Gould, associate professor of urology at UC Davis, who was not involved in the research. (
  • A more recent study of 52 men with unexplained infertility in the Urology Journal found that after receiving 25 mg/day of L-carnitine for 3 months, their sperm counts increased by 64 percent. (


  • Artificial Insemination is a medical procedure usually used to treat infertility. (


  • During the physical exam, the doctor will look for varicoceles and any abnormalities that might cause infertility. (
  • Polycystic ovarian syndrome is the most common hormonal disorder among women of reproductive age and can cause infertility. (
  • About 25% of all infertility is caused by a sperm defect and 40-50% of infertility cases have a sperm defect as the main cause, or a contributing cause. (
  • Controversial cause of asthenospermia and male infertility. (
  • Your doctor will also look for physical problems that might cause infertility. (
  • Your healthcare provider will test both you and your partner to find the cause of infertility. (
  • Your provider does these tests to find the cause of sperm defects or health problems of the male reproductive system. (


  • For example, in one double-blind study, 60 men with abnormal sperm function were given either carnitine (as L-carnitine 2 g/day and acetyl-L-carnitine 1 g/day) or placebo for 6 months. (
  • Thus vitamin B 12 supplementation has been tried for improving fertility in men with abnormal sperm production. (

reproductive system


  • An Australian study (2) led by Dr. Ann Clark assessed the vitamin D levels of 794 men visiting an infertility clinic in Sydney, and showed that over one third were deficient. (


  • Researchers said the risk remained constant over time, suggesting that sperm abnormalities had been present many years before the diagnosis of cancer, they conclude there may be common risk factors for poor sperm quality and testicular cancer and suggest these factors may be present in the developing male foetus. (
  • The odds ratio for an association of Gulf war service with a general diagnosis of type I male factor infertility should have been 1.16 (95% confidence interval 0.74 to 1.82), as correctly given in table 3. (
  • The advantage of serum AMH compared with serum TSH is the very little variation throughout the menstrual cycle, which makes it a useful tool in infertility diagnosis. (

healthy sperm

  • Problems with making healthy sperm are the most common causes of male infertility. (


  • A survey of samples from the U.S., United Kingdom and China showed that as many as a quarter of men worldwide carry two copies of the defective gene - which may significantly affect their fertility. (
  • A 2007 Chinese review of nine studies on L-carnitine and male infertility concluded that supplementation with this amino acid significantly improves sperm quality. (


  • Though there are no specific feature was linked to increased risk of testicular cancer, men with poor semen quality overall were between twice and three times as likely to develop testicular cancer. (
  • The researchers analysed the sperm quality of semen samples taken from over 32,000 men in England between 1960 and 1989. (
  • Male infertility plays a significant role, and our aim is to explore the influence of environmental factors and health status on semen quality," said senior author Germaine Buck Louis of NIH's Eunice Kennedy Shriver National Institute of Child Health and Human Development. (


  • Vitamin D - the sunshine vitamin - may be one of the most under-rated male fertility vitamins and one of the most deficient in men trying to conceive. (
  • Infertility is not being able to conceive after a year of regular, unprotected sex. (


  • A group of 123 of the vitamin D deficient men in the Australian study were followed for 3 months as they took vitamin D containing multivitamin supplements, antioxidants and lost weight. (
  • Men in the study group who agreed to make lifestyle changes and take dietary supplements had surprisingly good fertility outcomes. (
  • Should You Take Fertility Supplements for Male Infertility? (
  • If you are struggling with male infertility you may have been tempted by advertisements for fertility supplements. (
  • Growing evidence suggests that L-carnitine may be one of the more successful supplements for male infertility. (
  • While recent research points in favor of some fertility supplements for male infertility, it is important to recognize that they may not be a cure-all. (


  • Researchers found an average difference of less than half of a degree Fahrenheit in temperature of the scrotum between men who wore one underwear type or the other, with a margin of error larger than the difference. (
  • Researchers found that men who were diagnosed of high blood pressure had a lower percentage of normally shaped sperm, compared to men who reported no high blood pressure. (
  • But the UC Davis researchers found that many men carry a defective gene for DEFB126. (
  • A similarly sized 6-month, double-blind, placebo-controlled study, which involved men with low sperm counts, found benefits with carnitine (again as L-carnitine 2 g/day and acetyl-L-carnitine at 1 g/day) taken alone or carnitine combined with the anti-inflammatory drug cinnoxicam. (
  • In addition, a 2-month, double-blind, placebo-controlled, crossover study of 100 men with various forms of infertility found probable benefits with 2 g daily of L-carnitine. (


  • During the initial consult, both partners will be evaluated for infertility problems. (
  • Researhers from Britain examining the relationship between increasing rates of testicular cancer and decreasing sperm quality, have concluded men who have infertility problems have an increased risk of developing cancer. (
  • With infertility cases recording a speedy increase in north India, there are people who are minting money out of the people's problems. (
  • About half of those cases involve problems with male fertility. (
  • Problems with either of these may mean you have infertility. (


  • Growing, if not entirely consistent evidence, suggests that various forms of the supplement L-carnitine may improve sperm function and thereby provide benefit in male infertility. (
  • It's important to look at the ingredients of each male fertility supplement you are considering to see if their claims are backed up by science. (
  • Simply put, L-carnitine helps sperm cells generate the energy they need to function optimally," says Amos Grunebaum, M.D., a double board-certified OB/GYN who developed the formula for the male fertility supplement FertilAid . (


  • Of the men who reported taking two or more medications per day, 15 percent had sperm counts below 39 million. (


  • NIH's Buck Louis said, "The good news is that these factors, if they are confirmed to have negative effects on male fertility, can potentially be modified by medical care or changing job-related behaviors. (
  • About one-third of infertility is caused by male factors and one-third are caused by female factors. (


  • In the light of multiple studies confirming that most of us are vitamin D deficient - and that vitamin D receptors are replete in sperm - restoring optimal vitamin D levels could have a profound effect upon male-factor infertility. (
  • This is referred to as male factor infertility . (


  • Sunlight may be good for male as well as female fertility according to new research. (
  • However, the female should also be evaluated prior to the surgery - if her tubes are blocked or she has anovulation (no ovulation), or an ovarian reserve problem , surgery on the male is not indicated. (
  • You may have male infertility if your female partner has not become pregnant after you have tried for 1 year. (


  • A new study has revealed that workplace exertion, having high blood pressure, and taking multiple medications are some of the health risks that may reduce male fertility. (
  • A study by an international team of researchers led by UC Davis says that the loss of a protein that coats sperm may explain a significant proportion of infertility in men worldwide. (
  • According to one small double-blind study, the antioxidant carotenoid astaxanthin might enhance male fertility. (
  • The objective of the present study was to characterize hormone levels in an arbitrary menstrual cycle in women with unexplained infertility and male infertility, and to determine the predictive value for long-term possibility of live birth. (




  • Michael L. Eisenberg said, "As men are having children later in life, the importance of diseases people once thought as separate from fertility must be re-explored. (



  • Portions of the brain called the pituitary gland and hypothalamus, as well as male reproductive organs such as the testes affect fertility in men. (
  • It can affect a man, a woman, or both. (


  • Women are often held responsible for not conceiving and men shy away from tests. (
  • Results: There were no differences in hormone values and live birth rates between women with unexplained infertility and male infertility. (


  • In men, two spontaneously recurring deletions along a complex region of the Y chromosome are responsible for approximately 8% of cases of failed sperm production. (





  • Human male gamete endocrinology: 1alpha, 25-dihydroxyvitamin D3 (1,25(OH)2D3) regulates different aspects of 4. (


  • Human sperm anatomy: ultrastructural localization of 1alpha,25-dihydroxyvitamin D receptor and its possible role in the human male gamete. (