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  • immune response
  • The objective of immunotherapy is to direct the immune response away from humoral immunity and toward cellular immunity, thereby encouraging the body to produce less IgE antibodies and more Th1 regulatory T cells, which secrete IL-10 and/or TGF-beta, which skew the response away from IgE production. (wikipedia.org)
  • vaccine adjuvants
  • Combining immunotherapy (ie: checkpoint inhibitors, CAR-T cell therapy) and vaccine adjuvants (ie: interferon, saponin) with ablation synergizes the immune reaction, and can treat metastatic disease with curative intent. (wikipedia.org)
  • The resulting immunostimulation from cryoablation may not be sufficient to induce sustained, systemic regression of metastases, and can be synergysed with the combination of immunotherapy treatment and vaccine adjuvants. (wikipedia.org)
  • 2017
  • The Committee requests an update from AHRQ in the fiscal year 2017 CJ on research that will be undertaken pursuant to the workshop with the goal of identifying patient, healthcare provider, and systems barriers to initiation and adherence to allergy immunotherapy and developing interventions to address these problems. (aaaai.org)
  • allergy
  • This report should include information on planned AHRQ initiatives pertaining to the utilization of allergy immunotherapy to reduce the prevalence of asthma. (aaaai.org)
  • The AAAAI has been pushing for a multi-agency initiative of the U.S. Department of Health and Human Services (HHS) to examine the cost-effectiveness of allergy immunotherapy and methods to promote broader utilization. (aaaai.org)
  • efficacy
  • Randomized controlled studies in different cancers resulting in significant increase in survival and disease free period have been reported and its efficacy is enhanced by 20-30% when cell-based immunotherapy is combined with conventional treatment methods. (wikipedia.org)
  • antibodies
  • Monoclonal antibodies, a passive therapy, are the most widely used form of immunotherapy. (kidshealth.org)
  • While most immunotherapy research has focused on how antibodies' arms "reach out" and bind to immune checkpoint proteins, Dr. Dahan decided to focus on the "back end," and to examine how the antibodies' trunk interacts with Fc receptors. (weizmann.ac.il)
  • antigen
  • The diagram above represents the process of chimeric antigen receptor T-cell therapy (CAR), this is a method of immunotherapy, which is a growing practice in the treatment of cancer. (wikipedia.org)
  • Dendritic cells, a type of antigen presenting cell, are harvested from the person needing the immunotherapy. (wikipedia.org)
  • clinicians
  • In recent years, immunotherapy has become of great interest to researchers, clinicians and pharmaceutical companies , particularly in its promise to treat various forms of cancer . (wikipedia.org)
  • ASCO and NCCN have worked together to help clinicians and patients identify and treat the side effects of immunotherapy before they become dangerous. (cancer.net)
  • oncological
  • Although, cryoblation and immunotherapy has been used successfully in oncological clinical practice for over 100 years, and can treat metastatic disease with curative intent, it has been ignored in modern practice. (wikipedia.org)
  • Research
  • The new research, which is detailed in Biomaterials , showed that slow-release peptide gels could continuously deliver immunotherapy drugs to tumor sites for long periods of time. (rice.edu)
  • cells
  • An immunotherapy drug embedded in a slow-release hydrogel invented at Rice University in collaboration with the University of Texas Health Science Center at Houston (UTHealth) appears to be highly effective at killing cancer cells. (rice.edu)
  • These images show how cancer cells responded after three days of the timed release of immunotherapy drugs from Rice University's STINGel. (rice.edu)
  • A small molecule that can turn short-lived 'killer T-cells' into long-lived, renewable cells that can last in the body for a longer period of time, activating when necessary to destroy tumour cells, could help make cell-based immunotherapy a realistic prospect to treat cancer. (cam.ac.uk)
  • Immunotherapy uses a patient's own immune system to fight disease, and so immunotherapy outcomes may be predicted by immune markers such as T cells and PD-1/PD-L1 expression. (genengnews.com)
  • Advanced methods of molecular high-throughput analysis facilitate identifying the targets on cancer cells specifically and thus tailoring immunotherapies to the individual patient. (dkfz.de)
  • Specific Active Immunotherapy: The generation of cell-mediated and antibody immune responses focused on specific antigens expressed by the cancer cells. (wikipedia.org)