• rats
  • Hypophysectomy of rats resulted in a decreased binding of aminoacyl-tRNA by 40S ribosomal subunits. (biochemj.org)
  • Three weeks after hypophysectomy, performed at 5 or 8 weeks of age, the hypothalamic concentrations of GAL and GAL mRNA were reduced by 30-50% in both male and female rats, compared to age- and sex-matched controls. (uclouvain.be)
  • In the hypophysiotropic hypothalamus, the scarce GAL immunoreactivity normally observed in the arcuate nuclei was no longer detectable in hypophysectomized rats, and the intense GAL immunoreactivity of the external zone of the median eminence progressively decreased and completely disappeared 3 and 6 weeks after hypophysectomy. (uclouvain.be)
  • treatment
  • Believing that the metastatic progression of prostate cancer was related to exogenous testosterone after castration,[ What makes the Prostate Grow, WW Scott ] Scott and other embarked on experimentation with hypophysectomy (removal of the pituitary) in the treatment of advanced prostate cancer with mixed results - the first patient died 11 days after surgery, but two of the next five patients had a tangible response to surgery. (blogspot.com)