• These methods include transsphenoidal hypophysectomy, open craniotomy, and stereotactic radiosurgery. (wikipedia.org)
  • citation needed] In a transsphenoidal hypophysectomy, the pituitary gland or section of the pituitary gland is removed through the sphenoid sinus and out through the nose. (wikipedia.org)
  • Pituitary service: Transsphenoidal hypophysectomy" (PDF). (wikipedia.org)
  • Transsphenoidal hypophysectomy is a technically challenging surgery to perform, whereby a tumour affecting the pituitary gland is removed from the base of the brain through the soft palate in the mouth. (rvc.ac.uk)
  • Transnasal, transsphenoidal microsurgical hypophysectomy is a useful therapeutic procedure for patients with stage IV breast cancer which can be performed in selected patients with minimal morbidity and mortality. (psu.edu)
  • Transsphenoidal hypophysectomy however, has the potential to become the treatment of choice for dogs (and cats) with PDH. (vin.com)
  • In addition, cranial surgical procedures, such as transsphenoidal hypophysectomy, create situations where an alternative route of administration is needed as in cases of nasal packing or recovery from surgery. (druglib.com)
  • OBJECTIVES: To evaluate the efficacy and safety of transsphenoidal hypophysectomy in treating HST and DM in cats. (bvsalud.org)
  • ANIMALS: Sixty-eight client-owned cats with HST and DM treated by transsphenoidal hypophysectomy. (bvsalud.org)
  • Steady hands, nerves of steel: The endoscopic transphenoidal hypophysectomy is a delicate neurosurgical procedure. (the-rheumatologist.org)
  • Hypophysectomy is the surgical removal of the hypophysis (pituitary gland). (wikipedia.org)
  • We consider surgical hypophysectomy to be the optimal treatment option for acromegaly. (rvc.ac.uk)
  • Through offering surgical hypophysectomy as a treatment option, the RVC team have since successfully cured many diabetic acromegalic cats and cushingoid dogs. (rvc.ac.uk)
  • Neither adrenalectomy, hypophysectomy, nor 6-OHDA pretreatment altered the stress-induced reduction in renal PBR. (wustl.edu)
  • The RVC team was the first in the UK to treat cats with acromegaly (hypersomatotropism) and is now also routinely performing hypophysectomy in dogs (and the occasional cat) with pituitary-dependent Cushing's syndrome (hyperadrenocorticism). (rvc.ac.uk)
  • Hypophysectomy is an excellent treatment option for pituitary dependent Cushing's syndrome. (rvc.ac.uk)
  • We found that the rapid extinction of a CAR which occurs after posterior lobectomy or hypophysectomy can be prevented by treatment with ACTH, melanocyte stimulating hormone (α-MSH) or lysine vasopressin given during the extinction period 3 . (nature.com)
  • Prolactin receptors have been found in about 50% of human breast cancers, and their potential usefulness in selecting patients for hypophysectomy is being explored. (psu.edu)
  • Adrenal 5alpha-reductase activity was measured in female rats 0, 2, 5, and 6 days after hypophysectomy. (nih.gov)
  • The RVC's highly experienced team was the first veterinary centre in the UK to offer hypophysectomy surgery and have since performed the procedure on more than 100 pets. (rvc.ac.uk)
  • In dogs hypophysectomy is only rarely performed, it is currently possible only in very few specialized veterinary centers and requires a team approach, involving a neurosurgeon, an endocrinologist and a radiologist. (vin.com)
  • Hypophysectomy also only involves one general anaesthetic procedure, making it preferable to radiation therapy. (rvc.ac.uk)
  • Hypophysectomy is a definitive therapeutic procedure that should not be used as a last resort in the terminally ill patient. (psu.edu)
  • Medications that are given as hormone replacement therapy following a complete hypophysectomy (removal of the pituitary gland) are often glucocorticoids. (wikipedia.org)
  • Finally, when no adenoma is identified and selective removal is not possible, a partial hypophysectomy is performed by removing a quarter of the gland on each side and at the bottom of the gland, and preserving the central core of the gland. (stanford.edu)
  • Cet article procède à un examen des principales étapes dans l'histoire de la pathologie de la thyroïde, avec une brève discussion des aspects scientifiques concernant la glande thyroïde qui ont eu une importance historique, et de l'évolution de l'endocrinologie en tant que discipline à part entière. (who.int)
  • Hypophysectomy has been shown to induce improvement after antiestrogen treatment, particularly in those patients who have had an initial response to antiestrogens as well as in a few patients who failed to benefit. (psu.edu)
  • Estrogen receptor measurements in the tumor tissue have been shown to be useful in selecting patients for hypophysectomy as well as for antiestrogen therapy. (psu.edu)
  • The activity of phenylethanolamine-N-methyl transferase (PNMT) in the adrenal medulla declines markedly after hypophysectomy. (aspetjournals.org)
  • The decrease in adrenal PNMT activity caused by hypophysectomy is associated with corresponding decreases in the mass of chromaffin cells and in the amounts of epinephrine stored in the adrenal medulla and secreted in response to physiological stimuli. (aspetjournals.org)
  • These methods include transsphenoidal hypophysectomy, open craniotomy, and stereotactic radiosurgery. (wikipedia.org)
  • citation needed] In a transsphenoidal hypophysectomy, the pituitary gland or section of the pituitary gland is removed through the sphenoid sinus and out through the nose. (wikipedia.org)
  • Pituitary service: Transsphenoidal hypophysectomy" (PDF). (wikipedia.org)
  • Transsphenoidal hypophysectomy is an effective treatment for PDH in dogs. (slu.se)
  • Therefore, early diagnosis of PDH is important and transsphenoidal hypophysectomy is expected to have the best outcome when used as primary treatment for dogs with nonenlarged or moderately enlarged pituitaries. (slu.se)
  • If pituitary-dependent Cushing disease is confirmed, consultation with a neurosurgeon experienced in transsphenoidal hypophysectomy is indicated. (medscape.com)
  • Electrorhinomanometric evaluation of nasal functions in transseptal - transsphenoidal hypophysectomy. (ent-review.com)
  • Following on from the success of feline hypophysectomy procedures performed at the RVC to treat acromegaly and diabetes mellitus in cats, specialists at RVC Small Animal Referrals are using this procedure to treat dogs with pituitary-dependent hyperadrenocorticism (PDH, Cushing's disease). (rvc.ac.uk)
  • The long-term survival, disease-free fractions, and the complications of hypophysectomy in 150 dogs with pituitary-dependent hyperadrenocorticism (PDH) were examined in a prospective study. (slu.se)
  • I have undergone 2 pituitary surgeries with the second one resulting in a complete hypophysectomy. (cushingsbios.com)
  • I am one of those rare people who have had both a complete hypophysectomy and bilateral adrenalectomy. (cushingsbios.com)
  • The purpose of the study: is to study the frequency of postoperative hypopituitarism after transnasal hypophysectomy (THE) in patients with pituitary adenomas.Material and methods: Under our observation there were 24 patients with NFPA, of whom women were 14, men - 10. (endocrine-abstracts.org)
  • Finally, when no adenoma is identified and selective removal is not possible, a partial hypophysectomy is performed by removing a quarter of the gland on each side and at the bottom of the gland, and preserving the central core of the gland. (stanford.edu)
  • Thus adrenal-dependent rhythms in epidermal mitoses and rectal temperature persist after hypophysectomy, although their am- plitude is diminished. (nih.gov)
  • Hypophysectomy performed at any age causes atrophy of the thyroid and adrenal glands as well as asthenia and cachexia. (wikipedia.org)
  • This link was explored by Smith, who in 1930 reported that hypophysectomy of rats caused adrenocortical atrophy that was reversed by implanting pituitaries. (clinicalgate.com)
  • This cause this pair shares more than one minimal common illustrates a lattice-conforming structure, a.k.a. lattice ancestor (namely "Partial hypophysectomy" and "Tran- pair or lattice fragment. (nih.gov)
  • Of special interest are Dandy's scientific notes on hypophysectomy experiments. (jhmi.edu)
  • Initial endocrine therapies consisted of ablative procedures (oophorectomy, adrenalectomy, and hypophysectomy). (ascopost.com)
  • A lattice fragment in SNOMED CT's Hypophysectomy sub-hierarchy in Procedures. (nih.gov)
  • Erowid.org: Erowid Reference 1608 : Reversal of the effects of central nervous system depressants on EST by hypophysectomy. (erowid.org)
  • The purpose of this study was to determine the effects of hypophysectomy on caudal fin regeneration and to test the hypothesis that rates of regeneration decrease from the proximal to the distal areas of a fin. (wku.edu)
  • Effects of gonadotropin stimulation and hypophysectomy. (nih.gov)
  • In this study, we investigated the effect of pituitary hormones' depletion on cytokine synthesis after short- (21 days) and long- (35 days) term hypophysectomy (ST- HX and LT-HX, respectively). (uaeu.ac.ae)
  • IL-10 mRNA-expressing cells were increased after long-term hypophysectomy compared to controls. (uaeu.ac.ae)
  • There are various ways a hypophysectomy can be carried out. (wikipedia.org)
  • There are different ways of performing a hypophysectomy, depending on the problem that is being addressed. (medicalnewstoday.com)
  • The study shows that hypophysectomy diminishes the depressive responses and increases the excitatory responses to most of the drugs. (erowid.org)
  • In 1995, Matthew Zachary , an aspiring concert pianist and composer, was en route to graduate school to study film composition when he lost all fine-motor coordination in his left hand, was diagnosed with pediatric brain cancer (medulloblastoma), told he would never play again, and was given 6. (ascopost.com)
  • pophysectomy" and "Transsphenoidal share only one minimal common ancestor, "Hypophysectomy. (nih.gov)