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  • portal hypertension
  • Although rare, infiltration of inflammatory mast cells within the portal vein may lead to obstruction of the sinusoids resulting in non-cirrhotic portal hypertension. (gi.org)
  • Although systemic mastocytosis is uncommon, the subsequent development of hepatic involvement and non-cirrhotic portal hypertension are discussed. (gi.org)
  • 1 While the most common site of extracutaneous involvement in systemic mastocytosis is the bone marrow, hepatic involvement may result in hepatic fibrosis and sinusoidal, non-cirrhotic portal hypertension. (gi.org)
  • Laboratory testing to evaluate the etiology of portal hypertension (viral hepatitis panel, iron studies, alpha-1-antitrypsin, ceruloplasmin, and autoimmune markers including anti-nuclear antibody, immunoglobulin classes, smooth muscle antibodies, and antimitochondrial antibodies) was unremarkable. (gi.org)
  • Idiopathic portal hypertension associated with cytotoxic drugs. (bmj.com)
  • Four patients developed clinically important portal hypertension with histological features of idiopathic portal hypertension while they were receiving cytotoxic drugs for chronic myeloid leukaemia and Hodgkin's disease. (bmj.com)
  • There is an association between idiopathic portal hypertension and the use of chemotherapeutic agents, particularly thioguanine. (bmj.com)
  • There is no consensus about the optimal treatment of hepatocellular carcinoma (HCC) with cirrhotic portal hypertension, While this group of patients are classified as hepatectomy contraindication according to guidelines from National Comprehensive Cancer Network (NCCN) and American Association for the Study of Liver Diseases (AASLD). (clinicaltrials.gov)
  • With improvement of surgical technique, preoperative evaluation, and perioperative management,especially the Precise Hepatectomy Technique, more and more studies confirmed the safety of surgical intervention to hepatocellular carcinoma (HCC) patients with cirrhotic portal hypertension.However, most of the previous studies were either retrospective or with small samples. (clinicaltrials.gov)
  • The investigators project is a prospective randomized controlled trial, planning to compare the safety, efficacy and quality of life between precise hepatectomy and combined interventional treatment on hepatocellular carcinoma (HCC) with cirrhotic portal hypertension, to make a further understanding of optimal strategy. (clinicaltrials.gov)
  • however, portal hypertension may cause several other more common sources of upper gastrointestinal bleeding, such as esophageal varices and gastric varices. (wikipedia.org)
  • Several studies have found that patients with portal hypertension develop increased blood flow to the stomach. (wikipedia.org)
  • Since it treats the root cause of portal hypertension gastropathy, it has been putatively used for the condition. (wikipedia.org)
  • Congestion of the mucosa in other parts of the gastrointestinal tract can also be seen in portal hypertension. (wikipedia.org)
  • renal
  • At the end of this period of benign hypertension, MAP had risen from a control value of 91 +/- 4 to 132 +/- 8 mm Hg, in association with approximately a 10-fold increase in PRA and a 40% reduction in renal function. (ahajournals.org)
  • 1. The possible contribution of changes in cardiac β-adrenoceptors to alterations in cardiac responses to isoprenaline were investigated in hearts isolated from rats with renovascular hypertension (two-kidney, one-clip Goldblatt), 6, 12 and 18 weeks after renal artery clipping. (clinsci.org)
  • We hypothesized that the long-term effect of hypertension would compromise endothelium-derived nitric oxide (NO) and diminish its influence in controlling renal perfusion. (ahajournals.org)
  • model
  • 5. These results suggest that the reduction of ventricular β-adrenoceptor density in that model of hypertension was responsible, at least partially, for the lowered inotropic responsiveness of the same hearts to isoprenaline. (clinsci.org)
  • 2017
  • For a list of the members of the 2017 ACC/AHA Hypertension Guideline Writing Committee, see the Appendix . (annals.org)
  • The journal ranks #1 among all hypertension journals and #3 among journals in the Peripheral Vascular Disease category (2016 Journal Citation Reports (Clarivate Analytics, 2017). (wikipedia.org)
  • kidney
  • Hypertension affects approximately 75 million adults in the United States and is a major risk factor for stroke, myocardial infarction ( aka heart attack), Coronary artery disease (CAD) and other vascular diseases, diabetis II, and chronic kidney disease. (softpanorama.org)
  • At high concentrations cortisol can cross-react and activate the mineralocorticoid receptor, leading to aldosterone-like effects in the kidney, causing hypertension. (wikipedia.org)
  • Persistent hypertension is a major risk factor for hypertensive heart disease, coronary artery disease, stroke, aortic aneurysm, peripheral artery disease, and chronic kidney disease. (wikipedia.org)
  • high
  • Hypertension is high blood pressure. (netdoctor.co.uk)
  • In severe cases, where the diastolic pressure is so high that the person is not able to sleep at night and is showing systemic symptoms, then there may be need for taking hypertension medications to bring down the blood pressure immediately. (buzzle.com)
  • High blood pressure, also known as hypertension, affects millions -- including children and teens. (webmd.com)
  • Slideshow: A Visual Guide to High Blood Pressure Hypertension, or high blood pressure, is a common condition that will catch up with most people who live into older age. (webmd.com)
  • Preventing High Blood Pressure About one in every four American adults has high blood pressure -- also know as hypertension. (webmd.com)
  • A new study finds one-third of those diagnosed with resistant high blood pressure have what's called 'white coat' hypertension. (redorbit.com)
  • High blood pressure is the major sign in diagnosing gestational hypertension. (wikipedia.org)
  • Paroxysmal hypertension is episodic and volatile high blood pressure, which may be due to stress of any sort, or from a pheochromocytoma, a type of tumor involving the adrenal medulla. (wikipedia.org)
  • DOC has blood-pressure raising effects similar to aldosterone, and abnormally high levels result in hypokalemic hypertension. (wikipedia.org)
  • The slavery hypertension hypothesis proposes that disproportionately high rates of hypertension among blacks in the New World are due to natural selection preferring individuals who retain more sodium among black slaves during the Middle Passage. (wikipedia.org)
  • If hypertension is high enough to justify immediate use of medications, lifestyle changes are still recommended in conjunction with medication. (wikipedia.org)
  • severe
  • Some specialists in severe cases give saline IVs for the hypovolemia which then if that is the cause, brings the orthostatic hypertension down to a safe level. (wikipedia.org)
  • Methyldopa, hydralazine, and labetalol are most commonly used for severe pregnancy hypertension. (wikipedia.org)
  • Prevalence
  • Epidemiologist Dr. Richard Cooper has shown, for example, that the prevalence of hypertension among Nigerians is significantly lower than white Americans, while Germans and Finns have a higher prevalence than black Americans. (wikipedia.org)
  • Ocular
  • Ocular hypertension is the presence of elevated fluid pressure inside the eye (intraocular pressure), usually with no optic nerve damage or visual field loss. (wikipedia.org)
  • The Ocular Hypertension Treatment Study, a large, multicentered, randomized clinical trial, determined that topical ocular hypotensive medication delays or prevents the onset of Primary Open-Angle Glaucoma. (wikipedia.org)
  • Ocular hypertension is treated with either medications or laser. (wikipedia.org)
  • American Optometric Association - Ocular Hypertension webMD - Tonometry eMedicine - Glaucoma Overview Kass, M.A. (2002). (wikipedia.org)
  • Pheochromocytoma
  • Aortitis (inflammation of the aorta) with nephroptosis: "This orthostatic hypertension largely may be due to an activation of the renin system caused by nephroptosis and partly due to a reduced baroreflex sensitivity caused by aortitis" Pheochromocytoma Blood pressure variability is associated with progression of target organ damage and cardiovascular risk. (wikipedia.org)
  • Pheochromocytoma may cause abrupt ("paroxysmal") episodes of hypertension accompanied by headache, palpitations, pale appearance, and excessive sweating. (wikipedia.org)
  • Patients with paroxysmal hypertension who test negative for pheochromocytoma are said to be suffering from a clinical entity called "pseudopheochromocytoma. (wikipedia.org)
  • ischemia
  • Increased occurrence of silent cerebrovascular ischemia Systolic orthostatic hypertension increases stroke risk. (wikipedia.org)
  • Diastolic dysfunction is an early consequence of hypertension-related heart disease and is exacerbated by left ventricular hypertrophy and ischemia. (wikipedia.org)
  • Hypertension-related cognitive impairment and dementia may be a consequence of a single infarct due to occlusion of a "strategic" larger vessel or multiple lacunar infarcts due to occlusive small vessel disease resulting in subcortical white matter ischemia. (wikipedia.org)
  • clinical
  • The focus of this journal are different aspects of studying hypertension, which includes pathophysiology, blood pressure regulation, clinical treatment, and prevention. (wikipedia.org)
  • Original contributions span topics such as basic research, clinical studies, and population studies of hypertension. (wikipedia.org)
  • Hypertension is indexed in the following databases: BIOSIS Previews Chemical Abstracts 0009-2258 Chemical Abstracts Service - CASSI Current Contents - Clinical Medicine Current Contents - Life Sciences Science Citation Index SciSearch Hypertension home page. (wikipedia.org)
  • Hypertension is a risk factor for all clinical manifestations of atherosclerosis since it is a risk factor for atherosclerosis itself. (wikipedia.org)
  • mechanisms
  • For years, it has been the belief of the scientific community that gestational hypertension and preeclampsia were relatively unique to humans, although there has been some recent evidence that other primates can also suffer from similar conditions, albeit due to different underlying mechanisms. (wikipedia.org)
  • from these it has been realized that many mechanisms are potential causes of obesity-induced hypertension. (wikipedia.org)
  • The mechanisms of increased sympathetic nervous system activity in hypertension involve alterations in baroreflex and chemoreflex pathways at both peripheral and central levels. (wikipedia.org)
  • blood vessels
  • Recent work at Johns Hopkins involving a group of athletes aged 55 to 75 with mild hypertension has found a correlation of those with exercise hypertension to a reduced ability of the major blood vessels to change in size in response to increased blood flow (probably due to impaired function of the endothelial cells in the vessel walls). (wikipedia.org)
  • cause
  • These tumors or abnormalities of the adrenal glands cause excessive secretion of hormones that led to hypertension. (buzzle.com)
  • Hypertension in its early stages doesn t cause any noticeable symptoms. (bellaonline.com)
  • The underlying cause of gestational hypertension in humans is commonly believed to be an improperly implanted placenta. (wikipedia.org)
  • They showed that increasing the number of AGT increases the blood pressure and hence this may cause hypertension. (wikipedia.org)
  • ten genes have been identified which cause these monogenic forms of hypertension. (wikipedia.org)
  • A 2012 Cochrane review found medications for mild hypertension did not reduce the risk of death, stroke, or cardiovascular disease, but did cause side effects in 1 of every 12 people. (wikipedia.org)
  • Mild
  • Mild or moderate orthostatic hypertension may present without any symptoms other than the orthostatic hypertension BP findings. (wikipedia.org)
  • Evidence for medications in those with mild hypertension (between 140/90 mmHg and 160/100 mmHg) and no other health problems is less clear with some reviews finding no benefit and other reviews finding benefit. (wikipedia.org)
  • If there are benefits to treating people with mild hypertension they appear to occur primarily among those at highest risk, though all groups experience side effects at a similar rate (1 in 12). (wikipedia.org)
  • Treatment
  • There is not any official recommended treatments currently for orthostatic hypertension as the condition is still little known and can be due to different causes, hence treatment for those with this disorder is still trial and error experimental treatment. (wikipedia.org)
  • In general, the treatment of PPH is derived from the treatment of pulmonary hypertension. (wikipedia.org)
  • The first line of treatment for hypertension is identical to the recommended preventive lifestyle changes and includes dietary changes, physical exercise, and weight loss. (wikipedia.org)
  • Some programs aimed to reduce psychological stress such as biofeedback or transcendental meditation may be reasonable add-ons to other treatment to reduce hypertension. (wikipedia.org)