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  • patients
  • When we profiled the small RNAs circulating in the blood of healthy people versus heart failure patients, we found increases in levels of certain microRNAs expressed by muscle, including three known to originate only in the heart," says Kemal Akat, the first author and a postdoc in the lab. (medicalxpress.com)
  • The researchers found elevated levels of muscle-associated microRNAs in the blood but not in the heart tissue samples of the heart failure patients . (medicalxpress.com)
  • Clark, Perdue & List is actively investigating cases involving patients suffering from kidney damage as a result of using popular heart burn medications, including Nexium, Prilosec, and Prevacid, have been linked to kidney damage. (clarkperdue.com)
  • In patients with ischaemic heart disease, cathepsin-L is elevated in the serum and correlates with disease severity. (bmj.com)
  • Constitutional predisposition to vasovagal syncope: an additional risk factor in patients exposed to electrical injuries? (bmj.com)
  • Patients with a history of vasovagal reactions may be at high risk of developing lethal sinus node or conduction disturbances after electrical injuries. (bmj.com)
  • The aim of this study is to detect new brain injuries following heart surgery using an MRI brain scan, and by asking patients to perform a series of puzzles and language tasks assessing memory and brain function. (isrctn.com)
  • Tests will be performed before and after surgery for comparison with the patients' medical records and type of surgery to help identify the causes of brain injury. (isrctn.com)
  • Patients having heart surgery can join the study if it is safe for them to have an MRI scan, and their level of English is sufficient to complete the language tasks. (isrctn.com)
  • Patients also receive monitoring of brain blood flow during surgery using ultrasound, and we will obtain information about the patient's risk factors and type of surgery from medical records to explore potential causes of brain injury. (isrctn.com)
  • Patients with inherited high cholesterol have an increased risk of heart-related problems. (belmarrahealth.com)
  • H-FABP is more effective than Troponin T in risk stratifying Chronic Heart Failure patients. (wikipedia.org)
  • Langendorff
  • Rats were used for Langendorff isolated heart perfusion. (bmj.com)
  • Methods Langendorff perfused hearts were perfused with vehicle (normoxic control) or Sunitinib for 120 min and either stained with triphenyl-tetrazolium chloride to assess the level of infarct to risk size (n = 4) or analysed by real time PCR for the expression profile of MKK7 mRNA (n = 6) or analysed by western blot to assess the level of MKK7 activation (n = 4). (bmj.com)
  • myocardial infarction
  • Discussions of troponin often pertain to its functional characteristics[citation needed] and/or to its usefulness as a diagnostic marker[citation needed] or therapeutic target for various heart disorders in particular as a highly specific marker for myocardial infarction or heart muscle cell death. (wikipedia.org)
  • tissue
  • Researchers have revealed that experiments on pigs have shown that secretion from human embryonic stem cells can minimize heart injury by reducing tissue death by 60 per cent. (medindia.net)
  • The researchers profiled the microRNA in samples of blood and heart tissue from healthy people and people suffering from one of two types of heart failure , which develops when the heart's pumping action weakens, making it unable to deliver blood throughout the body. (medicalxpress.com)
  • The bleeding that can result from this can cause the thin layer of tissue around your heart to fill with fluid. (emedtv.com)
  • This layer of tissue, or 'heart sac,' is a limited space and is not meant to hold a large quantity of fluid. (emedtv.com)
  • 15kDa compared to 18, 80 and 37kDa for MYO, CK-MB and cTnT respectively, its rapid release into plasma after myocardial injury - 60 minutes after an ischemic episode, and its relative tissue specificity. (wikipedia.org)
  • Such tissue-regenerating properties of thymosin β4 may ultimately contribute to repair of human heart muscle damaged by heart disease and heart attack. (wikipedia.org)
  • mice
  • We have previously shown that high-dose glucocorticoid treatment reduces neointimal proliferation following arterial injury in mice, but is associated with increased local thrombosis. (bmj.com)
  • In mice, administration of thymosin β4 has been shown to stimulate formation of new heart muscle cells from otherwise inactive precursor cells present in the outer lining of adult hearts, to induce migration of these cells into heart muscle and recruit new blood vessels within the muscle. (wikipedia.org)
  • cardiopulmonary
  • In the early treatment model PD123319 attenuated cardiopulmonary injury by reducing alveolar septal thickness, pulmonary influx of inflammatory cells, including macrophages and neutrophils, medial wall thickness of small arterioles, and extravascular collagen III deposition, and by preventing RVH. (sigmaaldrich.com)
  • At low concentrations PD123319 attenuates cardiopulmonary injury by reducing pulmonary inflammation and fibrosis and preventing PAH-induced RVH but does not affect alveolar and vascular development in newborn rats with experimental BPD. (sigmaaldrich.com)
  • This observational study investigates brain injury following cardiac surgery involving cardiopulmonary bypass using transcranial Doppler (TCD) ultrasound, MRI, and cognitive testing. (isrctn.com)
  • tissues
  • After 17 hours, histopathological observations and left ventricular pressure-volume analysis to assess cardiac function with a Millar microtip pressure-volume conductance catheter were performed, and levels of biochemicals of the heart tissues were measured. (ahajournals.org)
  • Regeneration in humans is the regrowth of lost tissues or organs in response to injury. (wikipedia.org)
  • However ongoing research, particularly in the heart and lungs, suggests that there is hope for a variety of tissues and organs to eventually become regeneration-capable. (wikipedia.org)
  • There are some human organs and tissues that regenerate rather than simply scar, as a result of injury. (wikipedia.org)
  • artery
  • When cholesterol is stuck to the artery walls, passing through becomes far more difficult for blood - and the heart has to work harder, too. (belmarrahealth.com)
  • He died by getting horned in the back, breaking several of his ribs which severed an artery that led to his heart. (wikipedia.org)
  • The bull turned and hit him in the back (although he was not gored), breaking several of his ribs which severed an artery that led to his heart. (wikipedia.org)
  • result
  • The pharmaceutical injury attorneys at Clark, Perdue & List have represented hundreds of clients injured as a result of dangerous drugs and medical devices. (clarkperdue.com)
  • Lane Clyde Frost (October 12, 1963 - July 30, 1989) was an American professional bull rider and Professional Rodeo Cowboys Association (PRCA) member, who died in the arena at the 1989 Cheyenne Frontier Days Rodeo as a result of injuries sustained riding the bull Takin' Care of Business. (wikipedia.org)
  • The loan was cut short on 11 February, as a result of Carrick suffering an injury. (wikipedia.org)
  • attenuates
  • However, when persistent or too intense, ERs will induce and activate ER proapoptosis fators such as CHOP, caspase-12, This study aimed to elucidate Ischaemic postconditioning (IPO) whether attenuates I/R injury by suppressing ER stress-induced apoptosis. (bmj.com)
  • Researchers
  • Researchers in that study found that the men who used testosterone supplements had nearly a 30 percent increased risk of stroke, heart attack and death. (clarkperdue.com)
  • The researchers found that those with familial hypercholesterolemia - genetically determined high cholesterol - were more likely to suffer from tendon injury and pain, compared to those who did not. (belmarrahealth.com)
  • Scientists
  • Scientists at Singapore's Institute of Medical Biology (IMB) and Bioprocessing Technology Institute (BTI) and The Netherlands' University Medical Center Utrecht say that their findings may pave the way for a novel way to improve survival and recovery rate after a heart attack. (medindia.net)
  • Scientists in Thomas Tuschl's Laboratory of RNA Molecular Biology have linked an increase in certain microRNAs circulating in the blood with injury to cardiac muscle . (medicalxpress.com)
  • levels
  • The myocardial injury was evaluated by the levels of lactate dehydrogenase (LDH) and Creatine kinase (CK) in the coronary effluent. (bmj.com)
  • Compared to people with average LDL levels, those with the inherited kind had five times the higher risk for heart disease. (belmarrahealth.com)
  • human heart
  • They have revealed that they chose pigs for the study because it is the closest animal approximation to the human heart in terms of size, structure and function. (medindia.net)
  • Comparative RNA-sequencing analysis of myocardial and circulating small RNAs in human heart failure and their utility as biomarkers. (medicalxpress.com)
  • Research
  • Writing about their experiments in the journal Stem Cell Research, the team has revealed that heart function among the pigs administered the secretion from the stem cells was also found to improve during the study. (medindia.net)
  • It paves the way for improved recovery after heart attack -- a very practical outcome from stem cell research. (medindia.net)
  • This targeting of research to find ways of combating illness and benefiting people faster is at the heart of what we aim to do at IMB. (medindia.net)
  • Visit our research pages for current research about Heart injury treatments . (rightdiagnosis.com)
  • team
  • Despite the injury, Hayden earned first team All-Conference USA honors. (wikipedia.org)
  • On 8 July 2015, Carrick left Hearts to pursue regular first team football, with his contract having been terminated by mutual consent. (wikipedia.org)
  • death
  • Clark, Perdue & List is investigating claims for personal injury and wrongful death in connection with use of testosterone supplements. (clarkperdue.com)
  • If you or a loved one suffered a heart attack, stroke or death following use of a testosterone product, you may be entitled to compensation. (clarkperdue.com)
  • site
  • Dexamethasone-induced thrombosis at the site of intraluminal wire injury may be attributable to alterations in the endogenous fibrinolytic system rather than changes in platelet activity. (bmj.com)
  • These results suggest that beneficial inhibition of neointimal proliferation mediated by systemic glucocorticoid administration is negated in part by changes in fibrinolysis leading to large, semi-occlusive thrombi formation at the site of injury. (bmj.com)
  • found
  • They found three RNAs with potential for use as markers of heart injury. (medicalxpress.com)
  • This opens the possibility of finding many promising biomarkers like those we found from heart muscle , leading to a more universal test then the current monitoring of single proteins. (medicalxpress.com)
  • surgery
  • Frimpong-Boateng also runs a charitable foundation, the Ghana Heart Foundation, which is responsible for paying for heart surgery for some indigent Ghanaians under his care. (wikipedia.org)
  • 1992) Performed the first open-heart surgery in Ghana using the heart-lung-machine. (wikipedia.org)
  • Established the Ghana Heart Foundation to raise funds to assist those who cannot afford the cost of heart surgery. (wikipedia.org)
  • healthy
  • Signs of trouble: Postdoc Kemal Akat and colleagues used sensitive RNA sequencing techniques to profile the abundance of microRNAs in samples from healthy people and those suffering from heart failure. (medicalxpress.com)
  • potential
  • These multiple properties have provided the impetus for a worldwide series of on-going clinical trials of potential effectiveness of thymosin β4 in promoting repair of wounds in skin, cornea and heart. (wikipedia.org)
  • increase
  • Specific over expression of MKK7 in hearts has been shown to increase the sensitivity of cardiomyocytes to external stresses. (bmj.com)
  • care
  • 1992 - Established the National Cardio Thoracic Centre which is now recognised by the West African College of Surgeons to train heart surgeons, cardiologists, cardiac anaesthetists, operating room nurses, intensive care nurses, cardiac technicians, and other cardiothoracic technicians. (wikipedia.org)
  • member
  • A member of Hearts Under-20 side, Carrick made his Scottish Premier League debut on 4 August 2012, in a 2-0 win over St Johnstone. (wikipedia.org)
  • minor injuries
  • Where minor injuries and lesions occur, due to overexertion and/or overuse, massage can break them down quickly and effectively. (bodytech2u.com)
  • Wood was among the survivors of the Munich air disaster on 6 February 1958, suffering minor injuries, but played just one first-team game afterwards and was later sold to Huddersfield Town one year later. (wikipedia.org)
  • During 2007 and 2008, mononucleosis and minor injuries forced him to miss many major events, and his ranking dropped from No. 9 in January 2007 to No. 135 in January 2008. (wikipedia.org)
  • spinal
  • Two of the patients were diagnosed with amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease, and the third had a significant spinal cord injury. (labroots.com)
  • Neuropathy is typically associated with diabetes, as it's common for nerve damage to have occurred in individuals with high glucose storage, but neuropathy can also be attributed to chemotherapy, radiation, injuries, autoimmune diseases, spinal stenosis, cholesterol medication side effects, a build-up of toxins, and vascular disease. (swfhealthandwellness.com)
  • year
  • The main purpose of the client intake forms is to inform the massage professional of current and past health issues (within the year) and injuries so the massage professional can take special care to treat current issues and prevent additional injury. (bodytech2u.com)
  • Tofflemire was hurt the following year and was ultimately replaced by Ray Donaldson as the starter and the rest of his NFL career was plagued by injuries. (wikipedia.org)
  • The injury kept him out for a year but, before he could get back into the first team, he broke the same leg again. (wikipedia.org)
  • He had a three-year stint at South Melbourne in the 1960s but his appearances were restricted through injury. (wikipedia.org)
  • kept
  • He was then initially used as a jobber on NXT and was defeated by the likes of Roman Reigns and in a tag team match with Mike Dalton against The Ascension, before suffering an injury that kept him out of action for several months. (wikipedia.org)
  • third
  • They reached the group stage by defeating Hearts over two legs, but finished third in their group and therefore didn't make the knockout stages of the tournament. (wikipedia.org)