Hantavirus infections. Medical search. Frequent questions

The park is contacting visitors who stayed in the Signature Tent Cabins from mid-June through the end of August, advising them to seek immediate medical attention if they exhibit symptoms of Hantavirus Pulmonary Syndrome (HPS), a rare but serious illness caused by hantavirus. (cdc.gov)
The Centers for Disease Control and Prevention (CDC) issued a national health advisory, Notice to Health Care Providers: Hantavirus Pulmonary Syndrome Cases Associated with Staying in Yosemite National Park, California. (cdc.gov)
The purpose of this this advisory, which was distributed through CDC's Health Alert Network, is to inform state health departments and health care providers to be alert to the possibility of Hantavirus Pulmonary Syndrome in patients who may have had recent exposure to rodents or a history of travel to Yosemite National Park during June through August 2012. (cdc.gov)
Yosemite National Park announced that it continues to scale up its public health response and outreach as a result of 6 confirmed cases of Hantavirus Pulmonary Syndrome in individuals who visited the since June of this year. (cdc.gov)
The questions and answers below provide information for recent U.S. visitors to Yosemite and health care providers regarding the risk of exposure, diagnosis and testing for Hantavirus Pulmonary Syndrome (HPS) among recent visitors to Yosemite National Park, as well as links and phone numbers for further information. (cdc.gov)
Am I at risk for developing Hantavirus Pulmonary Syndrome? (cdc.gov)
This newly discovered viral infection was named Sin Nombre virus infection or Hantavirus Pulmonary Syndrome (HPS). (mcgill.ca)
Dolin R. California encephalitis, hantavirus pulmonary syndrome, hantavirus hemorrhagic fever with renal syndrome, and bunyavirus hemorrhagic fevers. (medlineplus.gov)
Eight case- patients experienced hantavirus pulmonary syndrome , of whom 5 required intensive care with ventilatory support and 3 died. (bvsalud.org)
Sin Nombre virus (SNV), as it is now known, is the primary agent responsible for Hantavirus pulmonary syndrome (HPS) and the deadliest member of the Hantavirus family. (medscape.com)
In Asia and Europe hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) whereas the American hantaviruses cause hantavirus pulmonary syndrome (HPS). (reagena.com)
Available at: https://www.dynamed.com/condition/hantavirus-pulmonary-syndrome. (epnet.com)
Sin Nombre virus (SNV) and Andes virus (ANDV) cause most of the hantavirus pulmonary syndrome (HPS) cases in North and South America, respectively. (nih.gov)
Hantavirus pulmonary syndrome-United States: updated recommendations for risk reduction. (ajtmh.org)
Using remotely sensed data to identify area at risk for hantavirus pulmonary syndrome. (ajtmh.org)
Hantavirus pulmonary syndrome: a clinical description of 17 patients with a newly recognized disease. (ajtmh.org)
The most common type of hantavirus illness found in the United States is Hantavirus Pulmonary Syndrome (HPS), the CDC says, and again, it's rare . (snopes.com)
The American virus causes hantavirus pulmonary syndrome: fever, chills, and severe muscle pain, followed by respiratory distress. (sciencedaily.com)
An adult male from Carroll County was diagnosed with hantavirus pulmonary syndrome in June of 1999. (vivu.tv)
It takes about one to five weeks (incubation period) for the signs and symptoms of hantavirus pulmonary syndrome to begin. (vivu.tv)
The deer mouse is a medically important species because it carries Hantavirus Pulmonary Syndrome (HPS). (vivu.tv)
Hantavirus pulmonary syndrome is a serious, often deadly, respiratory disease that has been found mostly in rural areas of the western United States. (klickitatcounty.org)
The deer mouse is the primary carrier of the virus that causes hantavirus pulmonary syndrome. (klickitatcounty.org)
You cannot become infected by being near a person who has hantavirus pulmonary syndrome. (klickitatcounty.org)
Symptoms of hantavirus pulmonary syndrome usually appear within 2 weeks of infection but can appear as early as 3 days to and as late as 6 weeks after infection. (klickitatcounty.org)
Hantavirus pulmonary syndrome is a rare disease, and most tourists are not at increased risk for hantavirus infection. (klickitatcounty.org)
In the past 20 years of surveillance for hantavirus in humans in the United States, 624 cases of hantavirus pulmonary syndrome (HPS) have been reported, 96% of which occurred in states west of the Mississippi River. (medscape.com)
A spokeswoman for the Washtenaw County health department told USA Today that the woman recovered from hantavirus pulmonary syndrome and is no longer in the hospital. (ksby.com)
Hantavirus was first discovered to be responsible for hantavirus pulmonary syndrome (HPS) in ill patients in the southwest United States in 1993. (ksby.com)
It is among the most deadly known human viruses: 30 percent to 40 percent of people who are diagnosed die from hantavirus pulmonary fever. (infectioncontroltoday.com)
The clinical syndrome caused by Sin Nombre virus (SNV) became known as Hantavirus pulmonary syndrome (HPS) or, more accurately, Hantavirus cardiopulmonary syndrome (HCPS). (medscape.com)
The virus causes hantavirus pulmonary syndrome, which begins with average flu symptoms that escalate dramatically to "shortness of breath and coughing as the lungs fill up with fluid" in four to 10 days, Besser said. (collegenews.com)

Members of the genus Hantavirus (family Bunyaviridae ) are commonly transmitted to humans through infected rodent excretions and may cause two severe human diseases: hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome ( 1 , 2 ). (cdc.gov)
Seoul hantavirus causes the renal syndrome. (msdmanuals.com)
Hemorrhagic fever with renal syndrome is a group of similar illnesses caused by hantaviruses. (msdmanuals.com)
In some people with hemorrhagic fever with renal syndrome, the infection is mild and does not cause symptoms. (msdmanuals.com)
Hemorrhagic fever with renal syndrome (HFRS) caused by pathogenic hantaviruses in Europe and Asia is often characterized by acute kidney injury (AKI) with massive proteinuria. (biomedcentral.com)
The more distantly related Hantaan, Seoul, Dobrava/Belgrade, and Puumala hantaviruses produce a distinct syndrome of hemorrhagic fever and renal failure (HFRS). (medscape.com)
Dobrava-Belgrade virus (DOBV) and Hantaan virus (HTNV) hantaviruses cause hemorrhagic fever with renal syndrome (HFRS). (reagena.com)
Hantaviruses cause two distinct diseases, depending on the agent: hantavirus cardiopulmonary syndrome (HCPS) in North and South America and hemorrhagic fever with renal syndrome (HFRS) in Europe and Asia. (einsteinmed.edu)
Hemorrhagic fever with renal syndrome (HFRS) is a zoonosis caused by rodent-borne hantaviruses. (slu.se)
A second type of illness caused by a hantavirus is Hemorrhagic Fever with Renal Syndrome (HFRS). (snopes.com)
European and Asian hantaviruses cause hemorrhagic fever with renal syndrome (HFRS), a group of similar illnesses with symptoms including, fever, kidney failure, and bleeding. (sciencedaily.com)
Hantavirus cardiopulmonary syndrome (HCPS) has symptoms that are often life threatening and include sudden-onset fever, headache, muscle aches, nausea, vomiting, cough, and shortness of breath. (tripprep.com)
viral-hemorrhagic-fevers fever with renal syndrome (HFRS), caused by different hantaviruses, begins like HCPS but does not have lung involvement. (tripprep.com)
Most hantavirus infections are caused by Sin Nombre virus, but cases of HPS caused by Bayou, Black Creek Canal, Monongahela, and New York viruses have been reported, and cases of domestically acquired hemorrhagic fever and renal syndrome caused by Seoul virus have also occurred. (medscape.com)
The respiratory syndrome caused by a hantavirus infection comes from breathing in small viral particles in the excrement of infected rodents. (infectioncontroltoday.com)
The clinical course of Hantavirus cardiopulmonary syndrome (HCPS) advances through several sequential stages. (medscape.com)
Clinical progression of hantavirus cardiopulmonary syndrome. (medscape.com)
Hantavirus cardiopulmonary syndrome (HCPS), however, was not recognized until May of 1993, when an unusual illness struck a Navajo tribe living on the border of New Mexico and Arizona. (medscape.com)
Hantavirus cardiopulmonary syndrome (HCPS) precautions during the 1993 outbreak. (medscape.com)
Geographic distribution and viral cause of Hantavirus cardiopulmonary syndrome (HCPS). (medscape.com)
Some strains of hantavirus, including those prevalent in the southwestern U.S. and South America, cause a cardiopulmonary syndrome that kills more than 30 percent of those they infect. (pewtrusts.org)
According to the CDC, "There is no specific treatment, cure or vaccine for hantavirus infection," but intensive care can help the patient if the syndrome is recognized early. (collegenews.com)

The prevalent human hantavirus disease in Sweden is nephropathia epidemica, which is caused by Puumala virus and shed by infected bank voles ( Clethrionomys glareolus ). (cdc.gov)
We analyzed the cellular consequences of hantavirus infection by measuring adhesion and migration capacity of human renal cells infected with Puumala (PUUV) or Hantaan (HTNV) virus. (biomedcentral.com)
The Puumala hantavirus is a causative agent of nephropathia epidemica (NE) and it is carried by the bank vole ( Myodes glareolus ). (reagena.com)
The researchers chose it from among more than 100 antibodies isolated from Swedish patients who had recovered from infection with Puumala virus, an HFRS-causing hantavirus endemic in northern Europe. (einsteinmed.edu)
This lead antibody recognized a portion of the Puumala virus spike glycoprotein complex that is also found in other hantaviruses: It broadly protected hamsters and voles challenged with hantaviruses responsible for both HCPS and HFRS. (einsteinmed.edu)
In Europe, Puumala hantavirus (PUUV) carried and shed by the bank vole (Myodes glareolus), is the most common cause of HFRS. (slu.se)

In the U.S., the type of hantavirus that causes HPS is known as Sin Nombre Hantavirus. (cdc.gov)
The host of the Sin Nombre hantavirus is the deer mouse ( Peromyscus maniculatus ), which is present throughout the western and central U.S., including Yosemite National Park. (cdc.gov)
Each spring, as rodents emerge from their burrows, Four Corners residents cleaning out storage sheds or woodpiles know to be on the lookout for tiny deer mice, which can carry the deadly Sin Nombre hantavirus. (unm.edu)
In the case of the Sin Nombre virus, first identified following an outbreak in the Southwest in 1993, the primary treatment of severe disease involves placing a patient on heart-lung bypass using extracorporeal membrane oxygenation (ECMO) to help them survive the infection. (unm.edu)
And while previous hantavirus cases have been concentrated in the Four Corners region, Bradfute says it appears that rodents elsewhere in New Mexico also carry the Sin Nombre strain. (unm.edu)
Bradfute notes that even if rodent populations carrying the hantavirus are more widespread than previously believed, "The infection rate for Sin Nombre is still very, very low. (unm.edu)
The first confirmed human case of Sin Nombre hantavirus has been reported in Michigan, the Michigan Department of Health and Human Services said. (ksby.com)
The most important hantavirus in the U.S. that causes HPS is the Sin Nombre virus, which is spread by the deer mouse and white-footed mouse. (ksby.com)

CDC is supporting the NPS response with testing of patient samples for evidence of hantavirus infection, providing guidance on clinical management of HPS and epidemiologic support for the response, and maintaining a Hantavirus Hotline for public inquiries. (cdc.gov)
The Texas Department of Health and CDC are continuing to investigate this illness by examining clinical materials using additional techniques and seeking evidence of hantavirus infection in rodents in the vicinity. (cdc.gov)
Except for illnesses in the Texas patient described in this report and in a person who had traveled to the four-state area in 1992 (4), no evidence of hantavirus infection has been detected in serologic tests conducted at CDC on specimens from 22 other persons with unexplained ARDS who resided outside the four-state area. (cdc.gov)
Serum samples from those afflicted demonstrated evidence of Hantavirus infection and within 10 weeks of the original outbreak, researchers had successfully developed a diagnostic test for the virus. (medscape.com)

The infection of renal cells by hantaviruses may contribute to proteinuria and may represent a determinant in the clinical course of HFRS. (biomedcentral.com)
People who become infected with this virus often exhibit relatively mild or no symptoms, but some develop HFRS ( https://www.cdc.gov/hantavirus/hfrs ), which can result in death in approximately 1-2% of HFRS cases. (cdc.gov)
Consequences of infection include respiratory failure (HCPS) or kidney failure (HFRS) that is severe enough to cause death. (tripprep.com)
European and Asian hantaviruses can infect humans, causing HFRS, which is a febrile illness with kidney involvement that, for some types of hantaviruses, may include bleeding manifestations. (tripprep.com)

Hantaviruses infect various species of rodents throughout the world. (msdmanuals.com)
We don't yet know what symptoms the Sangassou virus might cause or how virulent it is," said ter Meulen, "but we have already obtained preliminary evidence that the Sangassou virus can infect humans, because we identified hantavirus-specific neutralizing antibodies in [the blood] of humans living in the area where the virus was detected. (sciencedaily.com)
Several hantaviruses that can infect people have been identified in the U.S. and each hantavirus has a primary rodent host. (ksby.com)

Overview of Arbovirus, Arenavirus, and Filovirus Infections Arbovirus, arenavirus, and filovirus are viruses that are spread from animals to people and, with some viruses, from people to people. (msdmanuals.com)
The hantaviruses are RNA zoonotic viruses that are generally spherical in shape, measuring 70-100 nm in diameter, and can be identified by inclusion bodies and distinctive gridlike patterns on electron microscopy. (medscape.com)
Seoul virus is a member of the hantavirus group of rodent-borne viruses. (cdc.gov)
During late December 2016, CDC tested a blood specimen from the patient and confirmed that the infection was caused by Seoul virus, a member of the hantavirus family of rodent-borne viruses. (cdc.gov)
Notable vertebrate −ssRNA viruses include the Ebola virus, hantaviruses, influenza viruses, the Lassa fever virus, and the rabies virus. (wikipedia.org)
This novel hantavirus is related to viruses that cause severe disease in humans in Central and Eastern Europe. (sciencedaily.com)
Upregulation of PD-1 and its ligands PD-L1 and PD-L2 is observed during acute virus infection and after infection with persistent viruses including important human pathogens such as human immunodeficiency virus (HIV), hepatitis C virus (HCV), and hepatitis B virus (HBV). (frontiersin.org)
Infections with viruses of the genus ORTHOHANTAVIRUS. (bvsalud.org)
Hantaviruses are viruses that are primarily carried by rodents. (tripprep.com)
Hantavirus is a general term that classifies different types of viruses. (bioprepwatch.com)
In a paper published recently in the journal Viruses , Bradfute and colleagues in his lab and the UNM Museum of Southwest Biology reported that they have developed a tool that uses reverse-transcription quantitative real-time polymerase chain reaction technology to rapidly screen the tissue of wild-caught rodents for the presence of hantavirus. (unm.edu)
Within a few years, 4 additional disease-associated hantaviruses indigenous to the United States were described: Bayou, Black Creek Canal, New York, and Monongahela viruses. (medscape.com)
Hantaviruses (family Bunyaviridae , genus Hantavirus ) are rodent- and insectivore-borne viruses that are distributed in all continents except Antarctica. (medscape.com)
Hantaviruses are a family of viruses spread mainly by wild rodents and occur worldwide. (ksby.com)
Infections with viruses of the family Hantaviridae. (usda.gov)
About 20 viruses have been identified within the genus Hantavirus, family Bunyaviridae, but only 11 have been shown to cause human disease. (medscape.com)

Laboratory evidence of acute hantavirus infection has been confirmed in 16 patients who had onset of illness from January 1 through June 30, 1993. (cdc.gov)
Hantavirus was not seen in the Americas until 1993, when it killed approximately 20 people in the western United States. (sciencedaily.com)
National surveillance for hantavirus infections in the United States began in 1993, and HPS became nationally notifiable in 1995. (medscape.com)
Hantavirus is so rare that fewer than 600 cases have been reported in the United States since the virus was identified in 1993, according to ABC News. (collegenews.com)

Physicians from the Indian Health Service and the Centers for Disease Control and Prevention (CDC) determined that a rodent vector was responsible for the infection and identified the responsible virus as a member of the Hantavirus family. (medscape.com)
Through a review of literature and data from the hantavirus surveillance registry of the Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA, we have summarized the spectrum and distribution of human hantavirus infections in the United States through July 9, 2013. (medscape.com)

To identify host-cell genes needed for viral replication, Bates and Briley first used a less dangerous virus that was engineered to exhibit some characteristics of a member of the hantavirus group found in South America called Andes virus (ANDV). (infectioncontroltoday.com)

A previous report suggests that the prevalence of hantavirus-specific antibodies is low in humans in the United States (6). (cdc.gov)
Approximately 60,000-150,000 humans are hospitalized because of hantavirus infections worldwide each year, and to date, no specific treatment is available ( 4 ). (cdc.gov)
In a randomized and stratified study within northern Sweden, the prevalence of PUUV-specific immunoglobulin (Ig) M antibodies was 5.4% in adult humans, implying that approximately one eighth of human PUUV infections were diagnosed and reported ( 8 ). (cdc.gov)
Hantavirus can cause serious disease in humans. (ca.gov)
Hantaviruses are distributed worldwide and among the emerging pathogens that attract the attention of kidney research due to increasing numbers of cases and due to identification of novel species with pathogenic potential to humans [ 1 ]. (biomedcentral.com)
Hantavirus is a life-threatening viral infection spread to humans by rodents. (medlineplus.gov)
Hantaviruses are transmitted to humans via the aerosolized urine, faeces, or saliva of chronically infected carrier rodents. (reagena.com)
Hantavirus infection cannot be passed between humans. (epnet.com)
A man who passed away in China's Yunnan Province tested positive for hantavirus, a rare type of virus transmitted from rodents to humans, and news reports about that event raised fears that a new disease outbreak was looming. (snopes.com)
Instead, hantaviruses are spread from rodents to humans, and cases are extremely rare. (snopes.com)
Because hantavirus is not new and because it isn't transmitted between humans, no one should fear that a new outbreak of disease caused by hantavirus is looming. (snopes.com)
Researchers in the West African country of Guinea have discovered the first African hantavirus, a type of rodent- borne virus that can cause life-threatening infections in humans. (sciencedaily.com)
Researchers have discovered the first African hantavirus, a type of rodent-borne virus that can cause life-threatening infections in humans when it is inhaled through aerosolized rodent urine or droppings. (sciencedaily.com)
Hantaviruses are mainly transmitted to humans via inhalation of aerosols of contaminated rodent urine and (possibly) feces. (tripprep.com)
The disease is caused by a hantavirus that is carried by rodents and passed on to humans through infected rodent urine, saliva, and droppings. (klickitatcounty.org)
We now understand that several hantaviruses are endemic to North America, and infections in humans continue to occur where humans come into contact with infected rodents. (medscape.com)
[ 4 ] It is not known if all hantaviruses cause disease in humans. (medscape.com)
[ 5 ] All known New World hantaviruses pathogenic to humans, including SNV and Andes virus, cause HPS, in which the primary organ affected is the lungs. (medscape.com)
Salmonella infections can be transmitted to humans, even if the infected gerbil does not seem sick. (msdvetmanual.com)
Hantavirus infections are associated with domestic, occupational, or recreational activities that bring humans into contact with infected rodents. (ksby.com)
In addition, I will examine whether these key host factors also influence infection by other hantaviruses not currently known to cause disease in humans, and if they might impose barriers to transmission of hantaviruses from their animal reservoirs to humans. (pewtrusts.org)

Hantavirus is a virus that spreads through the urine, droppings (poop), or saliva of wild rodents, including deer mice , which are common in many parts of California. (ca.gov)
Particles containing hantavirus get into the air when mouse urine, saliva, or droppings are stirred up. (ca.gov)
Doctors suspect hantavirus if you have symptoms and you've been around rodents and their droppings. (msdmanuals.com)
Hantaviruses are spread through contact with infected rodents or their droppings. (msdmanuals.com)
The infection is spread when people have contact with rodents or their droppings or urine or possibly when they inhale virus particles in places with large amounts of rodent droppings. (msdmanuals.com)
Symptoms of hantavirus infection begin with sudden fever, headache, and muscle aches, typically about 2 weeks after exposure to the rodent droppings or urine. (msdmanuals.com)
However, visitors to rural areas and nature resorts, campers, hikers, and others who take part in activities outdoors can become exposed to rodent urine, saliva, and droppings and become infected with hantavirus. (klickitatcounty.org)
If your activities take you to areas where you may become exposed to rodent and their urine, saliva, or droppings, take the precautions listed in this sheet to prevent being exposed to hantavirus. (klickitatcounty.org)
HPS is caused by some strains of hantavirus and is a rare but severe and sometimes fatal respiratory disease that can occur one to five weeks after a person has exposure to fresh urine, droppings, or saliva from infected rodents," said Dr. Joneigh Khaldun, chief medical executive and chief deputy for health at MDHHS. (ksby.com)

The antibodies were originally isolated from Swedish patients who had been exposed to an Old World hantavirus, he said. (unm.edu)

Hantavirus is carried by rodents, particularly deer mice. (medlineplus.gov)

However, there are numerous other pathogenic hantaviruses. (medscape.com)
Currently, over 20 different human pathogenic hantaviruses have been identified worldwide. (reagena.com)

The current outbreak appears to be caused by a newly recognized hantavirus associated with Peromyscus maniculatus (deer mouse). (cdc.gov)
Genetic identification of a hantavirus associated with an outbreak of acute respiratory illness. (ajtmh.org)
Does China Have a 'New' Outbreak of Hantavirus? (snopes.com)
A new disease outbreak caused by the hantavirus has been detected in China. (snopes.com)
Though rare, a single human case of hantavirus infection, which is spread by rodents, is neither an "outbreak" nor a new phenomenon. (snopes.com)
However, a single reported case of hantavirus in China does not an outbreak make, and hantaviruses are hardly new. (snopes.com)
[ 5 ] In the United States, ≈90% of hantavirus infections are acquired through household or occupational exposures, [ 11 ] although a 2012 outbreak among Yosemite National Park visitors is a noteworthy example of recreational hantavirus exposure. (medscape.com)

rarely, Andes hantavirus in southern South America spreads directly between people in close physical contact. (msdmanuals.com)
[ 1 ] but, except for the Andes hantavirus, have not been shown to be capable of human-to-human transmission. (medscape.com)
Andes virus is the only person-to-person transmittable hantavirus. (reagena.com)
[ 10 ] The only hantavirus species with evidence of human-to-human transmission is Andes virus, which is endemic to South America. (medscape.com)

A fatal case of hantavirus infection occurred in China in March 2020. (snopes.com)
No case of Hantavirus infection was found. (ersjournals.com)

As of November 1, 2012 the National Park Service (NPS) has announced a total of 10 confirmed cases of hantavirus infection in people who recently visited Yosemite National Park. (cdc.gov)
A few cases of hantavirus infection, spread by pet or laboratory rats, have occurred in the United States, Canada, and Europe. (msdmanuals.com)

American hantaviruses cause HCPS, a severe infection affecting the lungs and the heart. (tripprep.com)
Five of the "New World" Hantaviruses cause HCPS in North America, while a few others cause disease in Central America and South America. (medscape.com)
SNV is the prototypical New World Hantavirus and is the cause of the vast majority of cases of HCPS in the United States (see the image below). (medscape.com)

Severe infections with hantaviruses HTNV, Dobrava-Belgrade virus (DOBV), or PUUV are characterized by AKI with massive proteinuria. (biomedcentral.com)

Continuous public awareness and rodent control and exclusion are key measures in minimizing the risk for hantavirus infection in areas inhabited by deer mice . (bvsalud.org)

Ecologic factors that mediate hantavirus distribution and maintenance in rodent host populations are not well known, but local variations of hantavirus antibody prevalence within host populations have been observed ( 3 ). (cdc.gov)
Each hantavirus species is carried primarily by a distinct rodent host. (reagena.com)

In contrast to hantavirus illnesses, COVID-19 has encircled the globe in a matter of months since its initial detection in late 2019. (snopes.com)

There are different types of hantavirus in different parts of the world. (msdmanuals.com)
Like each of the more than two dozen other types of hantavirus, Sangassou virus is carried by only one host species-limiting its spread to the natural range of the African wood mouse, from southern Guinea across parts of Sierra Leone, Liberia, and Ivory Coast, to Ghana. (sciencedaily.com)

Healthcare providers who suspect hantavirus infection in a patient should contact their state or local health department. (cdc.gov)

Surprisingly, after trapping various types of rodents, researchers confirmed that this lethal Hantavirus emerged from mice and some rats. (mcgill.ca)
CDC and health officials from Wisconsin and Illinois are conducting an investigation of Seoul virus infections among pet rats and persons exposed to rats at rat-breeding facilities in Wisconsin and Illinois. (cdc.gov)
CDC currently recommends testing of all persons who report recent or current illness after (1) handling rats from a facility with Seoul virus infection that was confirmed by laboratory testing (either rat or human), or (2) handling rats from a facility that sold rats to a facility with Seoul virus infection. (cdc.gov)
Testing is also offered to persons without illness but (1) who are reporting exposure to rats from a facility with Seoul virus infection that was confirmed by laboratory testing, or (2) who are reporting exposure to rats from a facility that sold rats to a facility with Seoul virus infection but where no illness has been reported. (cdc.gov)
A follow-up investigation of rat breeders who supplied the initial patient's rats revealed six additional human cases of Seoul virus infections occurring at two Illinois rat-breeding facilities. (cdc.gov)
Persons at risk of Seoul virus infection due to exposure to infected rats are also being identified. (cdc.gov)
Rats are carriers of disease, and can spread infections to human beings. (horizonpestcontrol.com)
Rats are known to spread infections such as Hantavirus, Salmonella, and Weil's disease. (horizonpestcontrol.com)

Hantavirus infects wild rodents throughout the world. (msdmanuals.com)
Hantavirus is spread from wild rodents to people. (klickitatcounty.org)

Previously, two well-characterized hantaviruses had been isolated from different species in the United States: Seoul virus from Rattus norvegicus (Norway rat) and Prospect Hill virus from Microtus pennsylvanicus (meadow vole) (5). (cdc.gov)
There are several species of hantavirus. (msdmanuals.com)
The particular organs affected are related to the specific species of Hantavirus. (medscape.com)
In recently published research, Bradfute and his colleagues have developed new gene sequencing methods to confirm the presence of hantavirus, discovered that the virus may also be carried by other rodent species, including house mice, brush mice, white-footed mice, piñon mice and chipmunks, and even identified a potential therapy for an illness that, until now, has had no cure. (unm.edu)

Symptoms of hantavirus infection can be mild or severe, depending on whether a person's lungs become infected. (ca.gov)
The virus can cause severe infections of the lungs (with cough and shortness of breath) or kidneys (with abdominal pain, and sometimes kidney failure). (msdmanuals.com)
No therapies are available for the 50,000 severe and often fatal infections caused each year by rodent-borne hantaviruses, a diverse and globally distributed group of emerging viral agents. (einsteinmed.edu)

The infection starts with sudden fever, headache, muscle aches, and sometimes abdominal symptoms, which may be followed by a cough and shortness of breath or by kidney problems. (msdmanuals.com)
Abstract INTRODUCTION: Chikungunya fever is a condition resulting from infection by chikungunya virus (CHIKV), an Aedes sp. (scielo.br)

Editorial Note: The findings of the investigation described in this report suggest that acute hantavirus infection occurred in a resident of eastern Texas. (cdc.gov)
This case suggests that ARDS associated with acute hantavirus infection can occur in areas outside the southwestern United States. (cdc.gov)
Experimental evidence suggests that insufficient signaling through the PD-1 pathway promotes immunopathology during acute infection by exaggerating primary T cell responses. (frontiersin.org)
The role of the PD-1/PD-L1 axis during viral infections is further complicated by evidence that PD-L1 also mediates inflammatory effects in the acute phase of an immune response. (frontiersin.org)

In the Southeast, the cotton rat is known to carry hantavirus. (klickitatcounty.org)
Anyone who comes into contact with rodents that carry hantavirus is at risk for HPS and healthcare providers with a suspect case of hantavirus should contact their local health department to report the case and discuss options for confirmatory testing. (ksby.com)

In research published online on March 16 in Science Translational Medicine , Kartik Chandran, Ph.D. , Eva Mittler, Ph.D. , and other members of the Prometheus consortium identified a monoclonal antibody with potential for neutralizing many different hantaviruses. (einsteinmed.edu)

Overview of Viral Infections A virus is a tiny living organism. (msdmanuals.com)
Hemorrhagic Fevers Overview Hemorrhagic fevers are serious viral infections characterized by bleeding (hemorrhage). (merckmanuals.com)

However, the detailed mechanisms of renal impairment induced by hantaviruses are not well understood. (biomedcentral.com)
The direct impairment of migration capacity of renal cells by hantaviral N proteins may contribute substantially to proteinuria observed in the clinical picture of hantavirus infection. (biomedcentral.com)
However, the underlying mechanisms and effects of hantavirus infection on human renal cells have not been investigated so far. (biomedcentral.com)
To identify the consequences of hantavirus infection, we analyzed adhesion and motility capacity of human renal cells infected with hantaviruses PUUV or HTNV. (biomedcentral.com)
Hantavirus particles are not found within the renal tubular cells of patients with HPS. (medscape.com)

In another new paper published in Science Translational Medicine , Bradfute joined an international consortium of investigators led by Kartik Chandran, PhD, professor of microbiology and immunology at Albert Einstein College of Medicine, that identified a monoclonal antibody that appears to provide broad protection against both Old and New World strains of hantavirus. (unm.edu)

Retrospective analyses indicate that HPS has been present in North America since as early as 1959, and Hantavirus infections have now been reported in at least 32 states in the United States, as well as in Canada and South America. (medscape.com)
Hantavirus is found in North, Central and South America. (epnet.com)

NPS public health officials believe that 9 of the 10 people with confirmed hantavirus infection were exposed to the virus while staying at the Signature Tent Cabins in Curry Village in Yosemite National Park. (cdc.gov)
The other park visitor with hantavirus infection was probably exposed to the virus while hiking or staying at the High Sierra Camps, located about 15 miles from Curry Village. (cdc.gov)
People can become infected with hantavirus when they breathe in air that is contaminated with the virus. (ca.gov)
In general, CDC recommends consideration of hantavirus testing in all persons with symptoms of Seoul virus infection and rat contact, even if the rat was not associated with a facility where a confirmed infection in a rat or human was reported. (cdc.gov)
In a viral infection, the virus uses your cells to grow and reproduce, making you ill in the process. (epnet.com)
Hantavirus infection is caused by a virus. (epnet.com)
Marburg and Ebola virus infections cause bleeding and organ malfunction. (merckmanuals.com)
Outbreaks of Ebola and Marburg virus infections started in Central and West Africa, probably because the infections are common in wild animals there. (merckmanuals.com)
Marburg virus infections have occurred in people exposed to bats (for example, in mines or caves). (merckmanuals.com)
How can I prevent Ebola and Marburg virus infection? (merckmanuals.com)
After finding the virus, the group cloned and sequenced it and compared it with known hantaviruses. (sciencedaily.com)
The new virus shares approximately 75 percent of its nucleotides and 85 percent of its amino acids with Asian and European hantaviruses. (sciencedaily.com)
It's crucial to identify cases and understand the symptoms of these infections to track the evolution of the virus and what health care workers should look out for. (infectioncontroltoday.com)

From January 1991 to December 1998, numbers, dates of infection, and demographic details of PUUV nephropathia epidemica cases within the northern region (i.e., the counties of Norrbotten, Västerbotten, Jämtland, and Västernorrland) were obtained from laboratory reports from the Departments of Clinical Virology and Clinical Microbiology in Umeå and Boden, Sweden, respectively. (cdc.gov)

Hantavirus can cause life-threatening lung and kidney infections. (msdmanuals.com)

The National Park Service (NPS) has announced that there are now 10 confirmed cases (including 3 deaths) of hantavirus infection in visitors to Yosemite National Park since June of this year. (cdc.gov)
Hantavirus, a flu-like disease spread by rodents, was the cause of death for a California man camping in Yosemite National Park, officials from the California Department of Public Health confirmed. (collegenews.com)

These symptoms occur in all instances of HPS infection. (cdc.gov)

Old World hantaviruses that are known human pathogens (e.g. (medscape.com)
A PLOS Pathogens paper by Penn microbiologists Paul Bates, PhD, and Kenneth Briley, PhD, published today reports that four proteins key to cholesterol synthesis and uptake are highjacked by the hantavirus to enter human host cells. (infectioncontroltoday.com)

About 38% of hantavirus infections are fatal (mortality rate). (vivu.tv)

Understanding this relationship may help forestall future human hantavirus outbreaks. (cdc.gov)
The monoclonal antibody appears to be a promising candidate for being developed into a "pan-hantavirus" therapy to protect against outbreaks by known or novel hantaviruses. (einsteinmed.edu)

Hantavirus infection is a viral disease that is spread from rodents to people. (msdmanuals.com)

In this area, nephropathia epidemica is, second to influenza, the most prevailing serious febrile viral infection. (cdc.gov)

Do all deer mice carry the hantavirus? (vivu.tv)
We're seeing [hantavirus] pretty frequently in rodents that are not deer mice. (unm.edu)

When visiting endemic countries, it may be useful to check for local hantavirus activity at the destination. (tripprep.com)

The potential of the Health Information System and its underutilization by stakeholders and researchers have been a barrier in diagnosing and reporting ZIKV infection and its complications. (scielo.br)
The researchers found that pre-treatment of human airway cells with a generic statin called mevastatin, which lowers cholesterol by a mechanism that does not involve the four proteins they identified, made the human airway cells less susceptible to ANDV infection. (infectioncontroltoday.com)

Organisms12

Diseases5

Chemicals and Drugs4

Analytical, Diagnostic and Therapeutic Techniques and Equipment2

Phenomena and Processes2

Information Science1

Health Care3

Geographicals5

Pulmonary32

Syndrome22

Puumala6

Nombre8

Evidence of hantavirus infection4

HFRS4

Infect3

Viruses16

19934

Centers for Diseas2

Member of the hantavirus group1

Humans21

Droppings9

Antibodies1

Carried by rodents1

Pathogenic2

Outbreak7

Andes4

Case of hantavirus infection2

Cases of hantavirus infection2

HCPS3

Dobrava-Belgrade1

Risk for hantavirus1

Rodent host2

20191

Types of hantavirus2

Suspect hantavirus1

Rats8

Wild rodents2

Species4

Severe3

Fever2

Acute4

Carry hantavirus2

Different hantaviruses1

Viral Infections2

Renal5

Strains1

South America2

Virus13

Clinical1

Kidney1

Yosemite Nati2

Occur1

Pathogens2

Fatal1

Outbreaks2

Spread from rodents1

Influenza1

Deer mice2

Endemic1

Researchers2