• sexually
  • This study tested whether taking a pill of tenofovir and emtricitabine (two antiretroviral medicines) was safe for sexually-active young adults in Botswana without HIV infection and whether it reduced their risk of getting an HIV infection. (clinicaltrials.gov)
  • Twelve hundred and nineteen healthy, sexually active women and men, 18-39 years old, without HIV infection were enrolled in Francistown and Gaborone, Botswana. (clinicaltrials.gov)
  • naive
  • This primary purpose of this study is to evaluate the safety, tolerability, and immune response to recombinant adenoviral serotype 35 (rAd35) and serotype 5 (rAD5) HIV-1 vaccines in Ad-5 naive and Ad-5 exposed HIV-uninfected adults. (clinicaltrials.gov)
  • Evaluate
  • This study will evaluate the safety and preliminary immune response to recombinant adenoviral serotype 35 and 5 HIV-1 vaccines in HIV-uninfected adults. (clinicaltrials.gov)
  • The purpose of the study is to adapt, implement, and evaluate an effective theoretically-based, high school HIV prevention program,Safer Choices, for higher risk youth in alternative schools. (clinicaltrials.gov)
  • duration
  • The appearance, identity, quantity, and duration of humoral antibodies against HIV and vaccinia virus. (clinicaltrials.gov)
  • The appearance, identity, quantity, and duration of cell-mediated immunity against HIV and vaccinia virus. (clinicaltrials.gov)
  • levels
  • The presence of detectable levels of a specific marker within the serum is considered seropositivity, while the absence of such levels is considered seronegativity. (wikipedia.org)
  • activity
  • Tenofovir 1% vaginal gel was chosen as a high priority microbicide candidate due to its activity in target cells for HIV infection of the vagina and cervix and the low frequency of local and systemic toxicity observed in a prior HIV Prevention Trials Network (HPTN) trial utilizing tenofovir 1% gel. (clinicaltrials.gov)