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  • agonist
  • Guanfacine is a highly selective agonist of the α 2A adrenergic receptor , with negligible affinity for any other receptor. (wikipedia.org)
  • Guanfacine is a selective alpha 2A -adrenoreceptor agonist that reduces sympathetic nerve impulses, resulting in reduced sympathetic outflow and a subsequent decrease in vasomotor tone and heart rate. (drugs.com)
  • This proposal aims to determine whether low does of the alpha-2A-adrenoceptor agonist guanfacine can improve deficits in prefrontally-mediated cognitive functions in healthy elderly subjects. (clinicaltrials.gov)
  • To determine whether low does of the α2A-adrenoceptor agonist guanfacine can improve deficits in prefrontally-mediated working memory and executive control functions, in healthy elderly subjects. (clinicaltrials.gov)
  • Selected examples are: Clonidine (mixed alpha2-adrenergic and imidazoline-I1 receptor agonist) Guanfacine, (preference for alpha2A-subtype of adrenoceptor) Guanabenz (most selective agonist for alpha2-adrenergic as opposed to imidazoline-I1) Guanoxabenz (metabolite of guanabenz) Guanethidine (peripheral alpha2-receptor agonist) Xylazine, Tizanidine Medetomidine Methyldopa Methylnorepinephrine Fadolmidine Dexmedetomidine The following agents are also listed as agonists by MeSH. (wikipedia.org)
  • disorders
  • Similarly, according to an American Academy of Child and Adolescent Psychiatry (AACAP) practice parameter for the treatment of children and adolescents with tic disorders, drug therapy, including guanfacine, is effective and recommended for the management of moderate to severe tics that severely impair quality of life in patients with chronic tic disorders, including Tourette syndrome. (drugs.com)
  • drug
  • Based on the European Society for the Study of Tourette Syndrome (ESSTS) and the Tourette Canada guidelines, drug therapy, including guanfacine, is effective and recommended for the management of Tourette syndrome to improve quality of life with tics that are painful or distressing, interfere with daily functioning, or cause sustained social or emotional problems. (drugs.com)
  • Guanfacine is a prescription drug. (healthline.com)
  • But in tests on monkeys, the guanfacine drug, which is normally used in the US to treat high blood pressure, helped to stop those rogue chemicals mounting up. (thefreedictionary.com)
  • hypertension
  • But giving them guanfacine , a medication that is already approved for treating hypertension in adults, significantly speeded up the process, making it more akin to that in young animals. (thefreedictionary.com)
  • medication
  • There are a number of situations in which guanfacine ER should not be taken, along with several safety concerns people should be aware of before taking the medication. (emedtv.com)