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  • Colony Stimul
  • OTC BB: DRUG) today announced that it has entered into an agreement with Suzhou Zhongkai Bio-Pharmaceuticals Company Limited ("Zhongkai") to in-license the exclusive right to commercialize its Recombinant Human Granulocyte Colony Stimulating Factor ("rhG-CSF? (dragonpharmaceuticals.com)
  • cells
  • In agranulocytosis, the concentration of granulocytes (a major class of white blood cells that includes neutrophils, basophils, and eosinophils) drops below 500 cells/mm³ of blood. (wikipedia.org)
  • There can also be isolated neutropenias where only differentiated granulocyte precursors are affected as in the case of neoplastic proliferation of cytotoxic T cells or NK cells Accelerated destruction of neutrophils. (wikipedia.org)
  • immature granulocyte
  • Myelophthisis is suggested by the presence of red blood cells that contain nuclei or are teardrop-shaped (dacryocytes), or immature granulocyte precursor cells which indicates leukoerythroblastosis is occurring because the displaced hematopoietic cells begin to undergo extramedullary hematopoiesis. (wikipedia.org)
  • kinetics
  • 1. The intrasplenic kinetics of granulocytes, isolated in plasma and labelled in plasma with 111 In-tropolonate, have been studied in normal subjects, patients with negative studies for inflammatory disease and patients with positive studies, with the aim of identifying the nature of splenic activity seen after 111 In-labelled granulocyte administration. (clinsci.org)
  • tissue
  • We found that oral administration of BRO in a model of moderate-to-severe bronchoalveolar inflammation in rats attenuated the inflammatory response by reducing both systemic leukocytosis as well as local infiltration of granulocytes into lung tissue and alveolar space. (thefreedictionary.com)
  • human
  • In this context, a number of conclusions can be drawn from the data presented: (1) Exposure to 1 and 2 M glycerol at room temperature damages human granulocytes in a few minutes. (unt.edu)
  • 3) Human granulocytes show some sensitivity to dilution stresses since survival depends somewhat on the concentration of glycerol used and the severity of the dilution procedure. (unt.edu)
  • Mouse granulocyte-colony stimulating factor (G-CSF) was first recognised and purified in Walter and Eliza Hall Institute, Australia in 1983, and the human form was cloned by groups from Japan and Germany/United States in 1986. (wikipedia.org)
  • cell
  • To this end, T cell responses orchestrated by granulocytes via antigen presentation have been described and received considerable attention. (frontiersin.org)
  • The reasons for the sharp decrease in cell viability following incubation of frozen-thawed granulocytes at 37/sup 0/C are not known. (unt.edu)
  • blood
  • Granulocytes were isolated from whole blood using a commercial kit for positive selection (StemCell Technologies Inc. (thefreedictionary.com)
  • 4. The application of deconvolution analysis to the blood and splenic time-activity curves generated a splenic retention (or washout) curve consistent with dynamic exchange of granulocytes between blood and spleen. (clinsci.org)
  • 5. Taking splenic activity to be reversible, comparison of the 111 In signal from the spleen 40 min after injection of 111 In-labelled granulocytes with that given from the spleen after the injection of 111 In-labelled erythrocytes (relative to their respective blood levels) indicated that intrasplenic granulocyte transit time was 14.4 (± se 1.1) times that of erythrocytes. (clinsci.org)