Glomerulonephritis. Medical search. FAQ

membranoproliferative glomerulonephritis type
Membranoproliferative Glomerulonephritis type II {1:Abrera-Abeleda et al. (diseaseinfosearch.org)
Following organizations serve the condition "Membranoproliferative glomerulonephritis type 2" for support, advocacy or research. (diseaseinfosearch.org)
Finding the right clinical trial for Membranoproliferative glomerulonephritis type 2 can be challenging. (diseaseinfosearch.org)
The terms "Membranoproliferative glomerulonephritis type 2" returned 1 free, full-text research articles on human participants. (diseaseinfosearch.org)
High-speed ultrahigh-resolution OCT of Bruch's membrane in membranoproliferative glomerulonephritis type 2. (diseaseinfosearch.org)
Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). (nih.gov)

MPGN
Membranoproliferative glomerulonephritis (MPGN), also known as mesangiocapillary glomerulonephritis, is a pattern of glomerular injury viewed by light microscopy. (uptodate.com)
These issues will be reviewed here with the exception of MPGN due to complement-mediated disease (C3 glomerulopathies, including C3 glomerulonephritis and dense deposit disease, and C4 glomerulopathy). (uptodate.com)
See 'C3 glomerulopathies: Dense deposit disease and C3 glomerulonephritis' and 'C4 glomerulopathy' and 'Recurrence of idiopathic immune complex-mediated membranoproliferative glomerulonephritis (MPGN) after transplantation' . (uptodate.com)
Membranoproliferative glomerulonephritis (MPGN) was originally classified according to the findings on electron microscopy. (uptodate.com)
Membranoproliferative glomerulonephritis (MPGN) type 2 is characterized by electron-dense deposits in the glomerular basement membrane and drusen-like deposits in Bruch's membrane. (diseaseinfosearch.org)

Nephropathy
The renal histopathology was compatible with focal and segmental glomerulosclerosis (FSGS) in 39% (n=14), IgM nephro-pathy in 28% (n=10), mesengioproliferative glomerulonephritis (MesPGN) in 17% (n=6), mini-mal change disease (MCD) and C1q nephropathy (C1qNP) in 8% each (n=3 + 3) and IgA nephro-pathy in 3% (n=1). (mysciencework.com)
C3 glomerulonephritis/CFHR5 nephropathy is an endemic disease in Cyprus: clinical and molecular findings in 21 families. (nih.gov)

kidney disease
IgA Glomerulonephritis is a common autoimmune kidney disease which affects the glomeruli-the small tubes in the kidneys. (blogspot.com)

immune
IgA Glomerulonephritis is just the result of immune dysfunction. (blogspot.com)
In IgA Glomerulonephritis, immune dysfunction occurs when the innate immune system continuously send signals to make the adaptive system work, or the adaptive immune system loses self-control ability and work persistently. (blogspot.com)

Clinical
See 'Clinical presentation, classification, and causes of membranoproliferative glomerulonephritis' . (uptodate.com)
See 'Clinical presentation, classification, and causes of membranoproliferative glomerulonephritis', section on 'Classification based upon electron microscopy' . (uptodate.com)

Treatment
In: Treatment of Primary Glomerulonephritis, Oxford Medical Publications, Oxford 2009. (uptodate.com)

membranoproliferative
glomerulonephritis with hypercellularity of glomeruli due to proliferation of endothelial or mesangial cells, occurring in acute glomerulonephritis and membranoproliferative glomerulonephritis. (drugs.com)
renal changes are variable, including those of rapidly progressive and membranoproliferative glomerulonephritis. (drugs.com)
Membranoproliferative glomerulonephritis (MPGN), also known as mesangiocapillary glomerulonephritis, is a pattern of glomerular injury viewed by light microscopy. (uptodate.com)
See 'Clinical presentation, classification, and causes of membranoproliferative glomerulonephritis' . (uptodate.com)
See 'C3 glomerulopathies: Dense deposit disease and C3 glomerulonephritis' and 'C4 glomerulopathy' and 'Recurrence of idiopathic immune complex-mediated membranoproliferative glomerulonephritis (MPGN) after transplantation' . (uptodate.com)
Membranoproliferative glomerulonephritis (MPGN) was originally classified according to the findings on electron microscopy. (uptodate.com)
See 'Clinical presentation, classification, and causes of membranoproliferative glomerulonephritis', section on 'Classification based upon electron microscopy' . (uptodate.com)
Membranoproliferative glomerulonephritis. (uptodate.com)
Pathological examination of renal biopsy showed membranoproliferative glomerulonephritis. (hindawi.com)
We report a patient who developed membranoproliferative glomerulonephritis (MPGN) 6 years after the diagnosis of dermatomyositrs sine myositis. (hindawi.com)
By contrast, membranoproliferative glomerulonephritis has a similar name, but is considered a separate condition with a distinctly different causality. (wikipedia.org)
Membranoproliferative glomerulonephritis involves the basement membrane and mesangium, while membranous glomerulonephritis involves the basement membrane but not the mesangium. (wikipedia.org)
Membranoproliferative glomerulonephritis has the alternate name "mesangiocapillary hohki", to emphasize its mesangial character. (wikipedia.org)
Membranoproliferative glomerulonephritis ("MPGN"), also known as mesangiocapillary glomerulonephritis, is a type of glomerulonephritis caused by deposits in the kidney glomerular mesangium and basement membrane (GBM) thickening, activating complement and damaging the glomeruli. (wikipedia.org)
Play media Membranoproliferative glomerulonephritis involves deposits at the intraglomerular mesangium. (wikipedia.org)
Most cases of dense deposit disease do not show a membranoproliferative pattern, A 2012 review considers DDD to be in a continuum with C3 glomerulonephritis, one reason the use of type I to type III classification system is falling out of favour. (wikipedia.org)
Systemic lupus erythematosus is associated with low C3 and C4 Membranoproliferative glomerulonephritis usually has low C3. (wikipedia.org)

proliferative glomerulonephritis
Mesangial proliferative glomerulonephritis is a form of glomerulonephritis associated primarily with the mesangium. (wikipedia.org)
Upon urine examination, urinary sediment (proteinuria) can indicate proliferative glomerulonephritis, many cases of rapidly progressive glomerulonephritis need a renal biopsy to make a diagnosis. (wikipedia.org)
These diseases include systemic lupus erythematosus, acute proliferative glomerulonephritis, Henoch-Schönlein purpura and IgA nephropathy. (wikipedia.org)
Endocapillary proliferative glomerulonephritis is a form of glomerulonephritis that can be associated with nephritis. (wikipedia.org)
Acute proliferative glomerulonephritis is a disorder of the glomeruli (glomerulonephritis), or small blood vessels in the kidneys. (wikipedia.org)
Among the signs and symptoms of acute proliferative glomerulonephritis are the following: Hematuria: Oliguria Edema Hypertension Fever ( headache, malaise, anorexia, nausea. (wikipedia.org)
Acute proliferative glomerulonephritis (post-streptococcal glomerulonephritisis) is caused by an infection with streptococcus bacteria, usually three weeks after infection, usually of the pharynx or the skin, given the time required to raise antibodies and complement proteins. (wikipedia.org)
citation needed] Acute proliferative glomerulonephritis most commonly occurs in children. (wikipedia.org)
Complement fixation causes the generation of additional inflammatory mediators Complement activation is very important in acute proliferative glomerulonephritis. (wikipedia.org)
The following diagnostic methods can be used for acute proliferative glomerulonephritis: Kidney biopsy Complement profile Imaging studies Blood chemistry studies Clinically, acute proliferative glomerulonephritis is diagnosed following a differential diagnosis between (and, ultimately, diagnosis of) staphylococcal and streptococcal impetigo. (wikipedia.org)
Treatment of acute proliferative glomerulonephritis consists of blood pressure (BP) control:also a renal biopsy may be needed to be performed at some point. (wikipedia.org)

glomeruli
Glomerulonephritis (pronounced: gluh-mare-you-low-neh-FRY-tis) is a problem with tiny filtering units in the kidneys called glomeruli . (kidshealth.org)
In most cases of acute glomerulonephritis, the damage to the glomeruli will eventually heal. (kidshealth.org)
Glomerulonephritis (GN) is inflammation of the glomeruli, which are structures in your kidneys that are made up of tiny blood vessels. (healthline.com)
When the glomeruli become inflamed, it's called glomerulonephritis . (brennerchildrens.org)
Rapidly progressive glomerulonephritis (RPGN) is a syndrome of the kidney that is characterized by a rapid loss of renal function, (usually a 50% decline in the glomerular filtration rate (GFR) within 3 months) with glomerular crescent formation seen in at least 50% or 75% of glomeruli seen on kidney biopsies. (wikipedia.org)
Glomerulonephritis is a type of kidney disease caused by inflammation of the internal kidney structures (glomeruli). (dmoztools.net)
Glomerulonephritis is inflammation of the glomeruli. (wikipedia.org)

kidneys
Glomerulonephritis causes the kidneys to stop working properly. (kidshealth.org)
Glomerulonephritis ( GN ), also known as glomerular nephritis , is a term used to refer to several kidney diseases (usually affecting both kidneys). (wikipedia.org)
Glomerulonephritis (gluh-MARE-you-low-ne-FRY-tis) causes the kidneys to stop working properly, which can cause swelling (edema) throughout the body and other symptoms. (brennerchildrens.org)

biopsy
How doctors treat acute glomerulonephritis in teens depends on what's causing it, what tests (like a kidney biopsy) show, how severe any kidney damage is (based on the biopsy results), and what symptoms the patient has. (kidshealth.org)
Photomicrograph of a kidney biopsy from a person with crescentic glomerulonephritis showing prominent fibrocellular crescent formation and moderate mesangial proliferation in a glomerulus . (wikipedia.org)
Kidney biopsy from a 7-year-old child with acute poststreptococcal glomerulonephritis. (medscape.com)

mesangial
Minimal mesangial glomerulonephritis is a type of glomerulonephritis is seen in 10% to 25% of SLE cases, and is associated with mild clinical symptoms. (wikipedia.org)

Acute Poststreptococcal Glomerulonephritis
The workup in patients with suspected acute poststreptococcal glomerulonephritis includes tests to provide evidence of preceding streptococcal infection, renal function studies, and serologic studies (see Workup ). (medscape.com)
See also Acute Poststreptococcal Glomerulonephritis , Acute Glomerulonephritis , and Emergent Management of Acute Glomerulonephritis . (medscape.com)

crescentic glomerulonephritis
Most recently, two different groups of investigators have demonstrated that anti-MPO antibodies alone can cause necrotizing and crescentic glomerulonephritis. (wikipedia.org)

nephrotic
Membranous glomerulonephritis may cause either nephrotic or a nephritic picture. (wikipedia.org)

inflammation
Glomerulonephritis refers to an inflammation of the glomerulus , which is the unit involved in filtration in the kidney. (wikipedia.org)

Pathophysiology
In the pathophysiology of rapidly progressive glomerulonephritis the antineutrophil cytoplasmic antibodies (ANCA) interact with antigens in cytoplasm of neutrophils. (wikipedia.org)

causes
While acute glomerulonephritis has known causes, sometimes doctors don't know why people get chronic glomerulonephritis. (kidshealth.org)

urine
If you notice swelling, blood in your urine, or any other symptoms of glomerulonephritis, talk to a parent and make an appointment to see a doctor. (kidshealth.org)
Often, people don't know they have glomerulonephritis until a routine urine test finds it. (kidshealth.org)
Chronic glomerulonephritis can take several months or years to develop and is found through a urine test. (kidshealth.org)
Acute glomerulonephritis following streptococcal infection is characterized by the sudden appearance of hematuria , proteinuria , red blood cell casts in the urine, edema, and hypertension with or without oliguria. (medscape.com)

dense deposit
These issues will be reviewed here with the exception of MPGN due to complement-mediated disease (C3 glomerulopathies, including C3 glomerulonephritis and dense deposit disease, and C4 glomerulopathy). (uptodate.com)

mesangium
It should not be confused with membranous glomerulonephritis, a condition in which the basement membrane is thickened, but the mesangium is not. (wikipedia.org)

symptoms
With acute glomerulonephritis, these symptoms might come on suddenly, possibly after a skin infection or a case of strep throat. (kidshealth.org)
With acute glomerulonephritis, symptoms come on suddenly, possibly after a skin infection or a case of strep throat. (kidshealth.org)
In adults, the signs and symptoms of infection may still be present at the time when the kidney problems develop, and the terms infection-related glomerulonephritis or bacterial infection-related glomerulonephritis are also used. (wikipedia.org)
The following symptoms (signs) are consistent with complement deficiency in general: Recurring infection Auto-immune disorders Glomerulonephritis Joint problems (manifestation) Lung function (MBL variant alleles) Angioedema Dermatomyositis Vasculitis Anaphylactoid purpura Play media Vaccinations for encapsulated organisms (e.g. (wikipedia.org)

corticosteroids
These mechanisms are still under discussion, but the final effects appear to support the use of corticosteroids in certain patients with idiopathic glomerulonephritis (GN). (springer.com)
Treatment may involve corticosteroids, but up to half of people with focal segmental glomerulonephritis continue to have progressive deterioration of kidney function, ending in kidney failure. (wikipedia.org)
Therapy for rapidly progressive glomerulonephritis is done via corticosteroids and cyclophosphamide. (wikipedia.org)

rapidly
The condition may develop quickly, and kidney function is lost within weeks or months (called rapidly progressive glomerulonephritis). (aarda.org)
Arieff, A.I. and Pinggera, W.F.: Rapidly progressive glomerulonephritis treated with anticoagulants. (springer.com)
The epidemiology of rapidly progressive glomerulonephritis according to Hedger, et al. (wikipedia.org)

membranous
Membranous glomerulonephritis ( MGN ) is a slowly progressive disease of the kidney affecting mostly people between ages of 30 and 50 years, usually Caucasian. (wikipedia.org)
85% of MGN cases are classified as primary membranous glomerulonephritis -that is to say, the cause of the disease is idiopathic (of unknown origin or cause). (wikipedia.org)
Within membranous glomerulonephritis, especially in cases caused by viral hepatitis, serum C3 levels are low. (wikipedia.org)
Chlorambucil Cyclosporine Tacrolimus Cyclophosphamide Mycophenolate mofetil Rituximab Perhaps the most difficult aspect of membranous glomerulonephritis is deciding which people to treat with immunosuppressive therapy as opposed to simple "background" or anti-proteinuric therapies. (wikipedia.org)

clinically
The incidence of clinically detectable glomerulonephritis during an epidemic is up to 10% of children with pharyngitis and 25% of children with impetigo. (medscape.com)

antineutrophil
ANCA are linked to the pathogenesis of glomerulonephritis, antineutrophil cytoplasmic antibodies specificity is determined via (ELISA), with pANCA(antibody) directed against MPO Serum analysis often aids in the diagnosis of a specific underlying disease. (wikipedia.org)

infection
Poststreptococcal glomerulonephritis follows infection with only certain strains of streptococci, designated as nephritogenic. (medscape.com)
It is a common complication of bacterial infections, typically skin infection by Streptococcus bacteria types 12, 4 and 1 (impetigo) but also after streptococcal pharyngitis, for which it is also known as postinfectious or poststreptococcal glomerulonephritis. (wikipedia.org)

kidney failure
Glomerulonephritis also can cause kidney failure and kidney disease , but that's rare. (kidshealth.org)
Untreated glomerulonephritis can lead to kidney failure or chronic kidney disease , although this is rare. (brennerchildrens.org)

treatment
In: Treatment of Primary Glomerulonephritis, Oxford Medical Publications, Oxford 2009. (uptodate.com)

damage
The good news about glomerulonephritis is that most of the time it gets better on its own - and, if it doesn't, there's a lot that doctors can do to prevent further damage. (kidshealth.org)
If glomerulonephritis isn't caught early and treated, there's a chance of kidney damage or failure. (kidshealth.org)
During this procedure, a tiny sample of kidney tissue is removed and sent to a lab for testing to help find the cause of the glomerulonephritis and check for any kidney damage. (kidshealth.org)

cases
Many cases of glomerulonephritis get better on their own. (brennerchildrens.org)

people
A quarter of people with chronic glomerulonephritis have no history of kidney disease. (aarda.org)

find the cause
Doctors often know what's causing acute glomerulonephritis, but it can be difficult to find the cause of chronic glomerulonephritis. (brennerchildrens.org)

years
Glomerulonephritis can be acute (meaning it comes on suddenly) or chronic (developing over several months to years). (kidshealth.org)
Chronic glomerulonephritis can take several months to years to develop, and a person might not notice it right away (unless a doctor tests for it). (kidshealth.org)

conditions
This form of glomerulonephritis may be associated with conditions such as HIV and heroin abuse, or inherited as Alport syndrome. (wikipedia.org)

Often
Often, the exact cause of glomerulonephritis is unknown. (aarda.org)
Glomerulonephritis is often implied when using the term "nephritis" without qualification. (wikipedia.org)