• transcriptomic
  • CLC bio's software allows the user to analyze, visualize, and compare genomic, transcriptomic, and epigenomic data from all major high-throughput sequencing platforms such as Illumina, Life Technologies, Roche 454, Pacific Biosciences, and Complete Genomics. (wikipedia.org)
  • GeneLoc
  • GeneNote and GeneAnnot for transcriptome analyses, GeneLoc for genomic locations and markers, GeneALaCart for batch queries and GeneDecks for finding functional partners and for gene set distillations. (wikipedia.org)
  • chromosomes
  • The authors painted a series of individual human chromosomes from a DNA library with two different fluorophores in different proportions to test the technique, and also applied CGH to genomic DNA from patients affected with either Downs syndrome or T-cell prolymphocytic leukemia as well as cells of a renal papillary carcinoma cell line. (wikipedia.org)
  • Genetic variation is brought about, fundamentally, by mutation, which is a permanent change in the chemical structure of chromosomes. (wikipedia.org)
  • nucleotides
  • Rapidly accumulating evidence indicates that structural variations can comprise millions of nucleotides of heterogeneity within every genome, and are likely to make an important contribution to human diversity and disease susceptibility. (wikipedia.org)
  • Technical variations of chain-termination sequencing include tagging with nucleotides containing radioactive phosphorus for radiolabelling, or using a primer labeled at the 5' end with a fluorescent dye. (wikipedia.org)
  • large
  • This technique can also be used in evolution studies by identifying large structural variation between different populations. (wikipedia.org)
  • Investments in computer infrastructure from the 2003 CFI/Ontario Innovation Trust competition resulted in the establishment of new phases of the high-performance computing cluster (HPF) that is currently used by TCAG and many other users, to allow analysis of large genomic datasets arising from new microarray and sequencing technologies. (wikipedia.org)
  • molecular
  • Modern descriptions of biological evolution will typically elaborate on major contributing factors to evolution such as the formation of local micro-environments, mutational robustness, molecular degeneracy, and cryptic genetic variation. (wikipedia.org)
  • loci
  • Genetic variation within a population is commonly measured as the percentage of gene loci that are polymorphic or the percentage of gene loci in individuals that are heterozygous. (wikipedia.org)