• Eukaryotic
  • This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell, which is a major site of ribosomal RNA and snRNA biogenesis, but there is no corresponding visible structure in archaeal cells. (wikipedia.org)
  • sequences
  • Rapid accumulation of genome sequences creates opportunities for refining COGs but also represents a challenge because of error amplification. (beds.ac.uk)
  • Under a framework of the devised code, we quantify codon and amino acid usages from a large collection of 917 prokaryotic genome sequences, and associate the usages with its intrinsic structure and classification schemes as well as amino acid physicochemical properties. (biomedsearch.com)
  • Our results show that the algebraic representation of the code is structurally equivalent to a content-centric organization of the code and that codon and amino acid usages under different classification schemes were correlated closely with GC content, implying a set of rules governing composition dynamics across a wide variety of prokaryotic genome sequences. (biomedsearch.com)
  • Our analysis of ~10.5 million protein sequences from 2,928 genomes identified 436,360 SFams, many of which are not represented in other protein family databases. (biomedcentral.com)
  • While this is a tremendous benefit for biology, this deluge of genome sequences presents new challenges for the management, distribution and analysis of data. (biomedcentral.com)
  • This list of sequenced eubacterial genomes contains all the eubacteria known to have publicly available complete genome sequences. (wikipedia.org)
  • bacteria
  • One study analyzed 235 genomes of bacteria and determined that the z coordinate of the Z curve accounted for 99.9% of the genetic variance and the x and y coordinates were not meaningful in studying nucleotide composition. (wikipedia.org)
  • Archaeal cells have unique properties separating them from the other two domains of life, Bacteria and Eukaryota. (wikipedia.org)
  • genus
  • Pyrococcus C/D box small nucleolar RNA are non-coding RNA (ncRNA) molecules identified in the archaeal genus Pyrococcus which function in the modification of ribosomal RNA (rRNA) and transfer RNA (tRNA). (wikipedia.org)
  • bacterium
  • citation needed] D. audaxviator is a Gram positive sulfate-reducing bacterium (making it the first complete such genome). (wikipedia.org)
  • Genetic Variation
  • As indels are largely produced by unstable microsatellite repeats, which are fast-evolving and difficult to genotype accurately, a large compartment of functional genetic variation is not treated by genome-wide association studies, which focus on single nucleotide polymorphisms and at most a subset of non-repeat associated indels. (wikipedia.org)
  • novel
  • The resulting reduction in computational complexity enables us to rapidly identify novel protein families found in new genomes and to perform efficient, automated updates that keep pace with genome sequencing. (biomedcentral.com)
  • circular
  • The Archaeoglobus fulgidus genome is a circular chromosome roughly half the size of E. coli at 2,178,000 base pairs. (wikipedia.org)
  • database
  • A few of the listed genomes may not be in the INSDC database, but in other public databases[verification needed]. (wikipedia.org)
  • Genomes listed as "Unpublished" are in a database, but not in the peer-reviewed scientific literature. (wikipedia.org)
  • research
  • Genome Research. (wikipedia.org)
  • In 2010, The Scientist named the company and their first product the top life science innovation of the year, and the company received the 2010 Advanced Sequencing Technology Award from the National Human Genome Research Institute. (wikipedia.org)
  • unique
  • Other aspects of archaeal biochemistry are unique, such as their reliance on ether lipids in their cell membranes, including archaeols. (wikipedia.org)