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  • allow
  • Although rickettsiae are maintained in nature through arthropod vectors, they frequently infect vertebrates, which in turn allow new lines of vectors to acquire infection from the rickettsemic hosts. (cdc.gov)
  • efficient
  • Their intimate relationships with vector hosts ( Table 1 ) are characterized by efficient multiplication, long-term maintenance, transstadial and transovarial transmission, and extensive geographic and ecologic distribution. (cdc.gov)
  • Algorithm
  • To predict the remaining life of ball screw, a screw remaining life prediction method based on quantum genetic algorithm (QGA) and support vector machine (SVM) is proposed. (hindawi.com)
  • In this paper, a coarse-grained parallel genetic algorithm (CGPGA) is used to simultaneously optimize the feature subset and parameters for SVM. (hindawi.com)
  • Experiment results on 12 benchmark datasets show that our proposed approach outperforms genetic algorithm (GA) based method and grid search method in terms of classification accuracy, number of chosen features, number of support vectors, and running time. (hindawi.com)
  • gene therapy
  • Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy. (semanticscholar.org)
  • In addition to their use in molecular biology research, viral vectors are used for gene therapy and the development of vaccines. (wikipedia.org)
  • In the future, gene therapy may provide a way to cure genetic disorders, such as severe combined immunodeficiency, cystic fibrosis or even haemophilia A. Because these diseases result from mutations in the DNA sequence for specific genes, gene therapy trials have used viruses to deliver unmutated copies of these genes to the cells of the patient's body. (wikipedia.org)
  • In one of the early gene therapy trials in 1999 this led to the death of Jesse Gelsinger, who was treated using an adenoviral vector. (wikipedia.org)
  • encoding a gene
  • The present invention provides a method of inducing an immune response in a non-invasive mode, comprising the step of: contacting skin of an individual in need of such treatment topically by applying to said skin an immunologically effective concentration of a genetic vector encoding a gene of interest. (google.com)
  • Also provided is a method of inducing an anti-tumor immune response in an animal in need of such treatment, comprising the step of: contacting skin of said animal topically by applying to said skin an immunologically effective concentration of a vector encoding a gene which encodes an antigen which induces an anti-tumor effect in said animal following administration. (google.com)
  • insertion
  • Fig. 1) are most useful as genetic tools because after insertion they cannot independently continue to excise and re-insert. (wikipedia.org)
  • Artificial
  • Researchers are experimenting introducing a 47th (artificial human) alongside the standard 46 .Carrying substantial amounts of genetic code. (scribd.com)
  • classification
  • The extensive applications of support vector machines (SVMs) require efficient method of constructing a SVM classifier with high classification ability. (hindawi.com)
  • In addition, a new fitness function, which combines the classification accuracy obtained from bootstrap method, the number of chosen features, and the number of support vectors, is proposed to lead the search of CGPGA to the direction of optimal generalization error. (hindawi.com)
  • Support vector machines (SVMs), proposed by Vapnik [ 1 ], have become the references for many classification problems because of their flexibility, computational efficiency, and capability of handling high dimensional data. (hindawi.com)
  • refers
  • Pharming, a portmanteau of "farming" and "pharmaceutical", refers to the use of genetic engineering to insert genes that code for useful pharmaceuticals into host animals or plants that would otherwise not express those genes. (wikipedia.org)
  • tools
  • Related to his genomics work, Rubin's lab is notable for development of genetic and genomics tools and studies of signal transduction and gene regulation. (wikipedia.org)
  • feature
  • Combined with wavelet packet decomposition and isometric mapping (Isomap), the sensitive feature vectors are obtained and stored in database. (hindawi.com)
  • life
  • Whether you're a global ad agency or a freelance graphic designer, we have the vector graphics to make your project come to life. (vectorstock.com)
  • It is also postulated that HGT promotes the maintenance of a universal life biochemistry and, subsequently, the universality of the genetic code. (wikipedia.org)
  • In other words, HGT is the "power" that "watches over" the universality of the genetic code and forces it into a "lingua franca" of life on Earth. (wikipedia.org)
  • insert
  • Knockin technology is different from knockout technology in that knockout technology aims to either delete part of the DNA sequence or insert irrelevant DNA sequence information to disrupt the expression of a specific genetic locus. (wikipedia.org)
  • human
  • Adeno-associated virus-based vectors are much safer in this respect as they always integrate at the same site in the human genome. (wikipedia.org)
  • found
  • Gene knockin technology, on the other hand, alters the genetic locus of interest via a one-for-one substitution of DNA sequence information or by the addition of sequence information that is not found on said genetic locus. (wikipedia.org)