• study
  • Thirty loci were followed up by in silico replication (1,160 asthmatic and 10,858 nonasthmatic participants: Atherosclerosis Risk in Communities, the Framingham Heart Study, the British 1958 Birth Cohort, and the Dutch Asthma Study). (rti.org)
  • So far, to our knowledge, no large-scale genetic study of dementia with Lewy bodies has been done. (nottingham.ac.uk)
  • To better understand the genetic basis of dementia with Lewy bodies, we have done a genome-wide association study with the aim of identifying genetic risk factors for this disorder. (nottingham.ac.uk)
  • Interpretation Despite the small sample size for a genome-wide association study, and acknowledging the potential biases from ascertaining samples from multiple locations, we present the most comprehensive and well powered genetic study in dementia with Lewy bodies so far. (nottingham.ac.uk)
  • effects
  • Comparisons of two-locus and three-locus combinations indicated that cumulative effects ofQTLswere significant for all the three unsaturated fatty acids. (unl.edu)
  • method
  • 2. The method of claim 1, wherein ASR resistance locus 14 is identifiable by one or more of the markers NS0095012, NSOl 19675, and NS0102630. (google.com.au)
  • 5. The method of claim 4, wherein ASR resistance locus 15 is identifiable by one or more of the markers NS0093385, NSOl 18716, and NS0127833. (google.com.au)
  • 8. The method of claim 7, wherein ASR resistance locus 16 is identifiable by one or both of the markers NSOl 13966 and NSOl 18536. (google.com.au)
  • Our method, the extended Bayesian LASSO (EBL), introduces locus-specific regularization parameters and utilizes a parameterization that clearly separates the overall model sparsity from the degree of shrinkage of individual regression parameters. (genetics.org)