• signaling pathway
  • From the original setting of mouse ESC culture, scientists identified the active components leukaemia inhibitory factor (LIF) and bone morphogenic proteins (BMP), which maintain the pluripotency in ESCs through activating the Jak/Stat3 signaling pathway and inducing the inhibitors of differentiation (Id) genes, respectively [ 4 , 5 , 6 ]. (mdpi.com)
  • microarray
  • ConclusionsMultiple solutions now exist for whole-genome expression profiling of FFPE tissues, including both microarray- and sequencing-based platforms. (duhnnae.com)
  • The increased use of microarray expression profiling to study both the molecular biology of cancer and the cellular physiology of difficult-to-isolate cell types has led to a growing need for methods that allow the use of limiting quantities of RNA. (unimi.it)
  • Evaluation of TransPlex Whole Transcriptome Amplification method for microarray gene expression profiling / C. Peano, M. Severgnini, I. Cifola, E. Rizzi, G. De Bellis, C. Battaglia. (unimi.it)
  • biological
  • Current challenges can be expected to remain as RNA sequencing matures, and they will thus motivate ongoing research efforts into noise reduction and identification of robust, translationally relevant biological signals in expression data from FFPE tissues. (duhnnae.com)
  • These genes were involved in variable important biological processes including ion transport, cysteine metabolic process, apoptosis, DNA damage repair, etc. (duhnnae.com)
  • profiles
  • We tested reproducibility by comparing the expression profiles provided by U133 Plus 2.0 GeneChipsĀ® for 3 independently amplified RNA samples: a high degree of correlation between the replicates was obtained. (unimi.it)