• absorption
  • Gastrointestinal transit rate-related absorption of emepronium: a study in mice. (semanticscholar.org)
  • The gastrointestinal (GI) absorption in mice of the anticholinergic quaternary ammonium compound emepronium, assessed by the urinary excretion of radioactivity and unchanged drug, increased from 1% to 7% and from 0.5% to 5%, respectively, in the dose range 0.1 to 40 mg/kg, whereafter a plateau was reached. (semanticscholar.org)
  • Atropine sulphate given subcutaneously (1-50 mg/kg) more than doubled the urinary recovery of a small pharmacologically inactive oral dose of emepronium (5 mg/kg) and thus confirmed the transit rate-dependent absorption of emepronium. (semanticscholar.org)
  • The superimposed effect of the pharmacological action on the GI transit rate, derived from the inherent property of an anticholinergic drug, may be of special significance for a drug with a low degree of absorption and a high variability, such as has been observed in clinical trials with the quaternary drug emepronium (Cetiprin). (semanticscholar.org)
  • Effects
  • Effects of gastrointestinal transit on plasma concentrations of drugs from enteric-coated pellet formulations were demonstrated using pharmacokinetic models describing plasma concentrations of drugs from various enteric-coated pellet formulations. (oregonstate.edu)
  • Acacia ferments very slowly in the gut, and due to its polymeric nature does not disturb osmotic pressure, so it has a good gastrointestinal tolerance (it has no sudden and painful release of gas, and the total gas production is much lower than with FOS, for instance) and does not present any side effects at dosages up to 50 grams per day. (wikipedia.org)
  • study
  • The birds in this study were submitted for fluoroscopic examination to evaluate proventricular size and gastrointestinal motility as indicators of subclinical bornaviral changes, as part of a screening programme prior to sale as breeding animals. (bmj.com)
  • Total
  • Total gut transit as measured by the amount of radioactive marker excreted in the stools at 18 and 24 h was unaffected by the use of chilli or capsaicin. (nus.edu.sg)
  • results
  • The research results (see table) indicate that about 1 in 5 people have a slow transit (type 1 and 2 stools), while 1 in 12 has an accelerated transit (type 5 and 6 stools). (wikipedia.org)
  • food
  • The largest of these, indricotheres and proboscids, have been hindgut fermenters, which are believed to have an advantage over foregut fermenters in terms of being able to accelerate gastrointestinal transit in order to accommodate very large food intakes. (wikipedia.org)
  • patients
  • To reduce the risk of delayed GI transit and obstruction, patients should maintain adequate hydration during and in the days following a barium sulfate procedure. (drugs.com)
  • animals
  • In addition, we show that neither delta nor kappa receptor agonist given supraspinally or peripherally are able to inhibit GI transit in MOR-KO animals. (nih.gov)