NeuroblastomaTumorsBenign tumorAdrenal GanglioneuromaRetroperitoneal ganglioneuromaMalignantTumorSympathetic nervouNoncancerousNeuroblastomasSurgicalDiagnosisAsymptomaticImmunohistochemicalOccurImagingCitationPatientsTissueFoundImagesAppearanceRetroperitonealBenign ganglioneuromaDumbbell GanglioneuromaGanglioneuroblastomasParavertebralResectionGanglion cellsSpinalAdrenal massesCervicalSymptomsTumoursScanFindingsRareTypicallyNerveRarelyGoodCase reportSpread
Neuroblastoma8
- It is contained within the neuroblastic tumors group, which includes: Ganglioneuroma (benign), Ganglioneuroblastoma (intermediate), Neuroblastoma (aggressive). (wikipedia.org)
- Ganglioneuroblastoma is a transitional tumor on the intermediate spectrum of disease between ganglioneuromas and neuroblastomas, containing elements of both malignant neuroblastoma and benign ganglioneuroma. (medscape.com)
- A neuroblastoma transformed into a ganglioneuroma was well studied by the use of large sections which allowed the observation of the actual transformation of one element into the other. (jamanetwork.com)
- Ganglioneuroma (GN) is ranked by the International Neuroblastoma Pathology Classification as a benign tumor . (bvsalud.org)
- Pancreastatin immunoreactivity in favourable childhood neuroblastoma and ganglioneuroma. (interscienceinstitute.com)
- Ganglioneuroblastoma displays a level of maturation and differentiation that is intermediate between the highly aggressive neuroblastoma on one hand and the benign tumor ganglioneuroma at the other end. (webpathology.com)
- The specificity of our case is the benign evolution of an osteomedullary stage 4 neuroblastoma and its maturation into a ganglioneuroma 6 years after the end of chemotherapy. (lupinepublishers.com)
- In addition, the evolution of neuroblastoma is unlikely: the tumor can be aggressive and evolves rapidly into a metastatic disease, as it can be "nice" and undergoes regression or maturation (spontaneous or probably induced) into a benign tumor: the ganglioneuroma. (lupinepublishers.com)
Tumors10
- However, ganglioneuromas themselves are fully differentiated neuronal tumors that do not contain immature elements. (wikipedia.org)
- Ganglioneuromas most frequently occur in the abdomen, however these tumors can grow anywhere sympathetic nervous tissue is found. (wikipedia.org)
- Ganglioneuromas are rare tumors that most often start in autonomic nerve cells. (medlineplus.gov)
- Ganglioneuromas (GN) and ganglioneuroblastomas (GNB) are tumors of the sympathetic nervous system that originate from neural crest sympathogonia, which are completely undifferentiated cells of the sympathetic nervous system. (medscape.com)
- Along with neuroblastomas , ganglioneuromas and ganglioneuroblastomas are collectively known as neuroblastic or neurogenic tumors . (medscape.com)
- The benign (ganglioneuromas) and malignant (ganglioneuroblastomas) forms of these tumors are virtually identical radiologically. (medscape.com)
- A ganglioneuroma (GN) is the rarest and most benign of the neuroblastic tumors and originates from neural crest cells wherever sympathetic nervous tissue exists, such as in the retroperitoneum and adrenal gland. (unito.it)
- x000D_ Discussion: Ganglioneuromas are a slow growing rare benign tumors that originate from the neural crest and typically affect young adults, mostly (80%) being diagnosed before 40 years old. (auanet.org)
- As in the present case, ganglioneuromas are usually found to be silent, slow growing tumors that are discovered incidentally or by mass compression effect if they become large. (auanet.org)
- Ganglioneuromas (GNs) are well-differentiated, rare benign tumors of neural crest origin and are, for the most part, considered to be the benign equivalent of neuroblastomas. (erdogan.edu.tr)
Benign tumor2
- Ganglioneuroma is a rare and benign tumor of the autonomic nerve fibers arising from neural crest sympathogonia, which are completely undifferentiated cells of the sympathetic nervous system. (wikipedia.org)
- An Adrenal Ganglioneuroma (AGN) is an extremely rare, hormonally silent benign tumor. (journalcra.com)
Adrenal Ganglioneuroma2
- Adrenal ganglioneuroma with multifocal retroperitoneal extension: a challenging diagnosis. (unito.it)
- Here, the present authors report a case of giant adrenal ganglioneuroma in a 25-year-old female presenting with vague right side abdominal pain, after abdominal computed tomography (CT) scanning, the patient underwent an open right adrenalectomy and histopathological examination further confirmed the lesion as giant AGN, which measured 16 cm * 13 cm* 10 cm. (journalcra.com)
Retroperitoneal ganglioneuroma4
- To our knowledge this is the first described case of robotic excision of a retroperitoneal ganglioneuroma. (auanet.org)
- 1)_x000D_ Objective: To present a case of retroperitoneal ganglioneuroma, describe its surgical management and reviwe current literature. (auanet.org)
- Although retroperitoneal ganglioneuroma is a benign lesion, it requires surgical excision for definite treatment, preferable through minimally invasive approach. (auanet.org)
- Robotic and standard surgical intervention as adjunct therapies for retroperitoneal ganglioneuroma resection: a case report. (bvsalud.org)
Malignant2
- An urban legend: Malignant transformation caused by radiotherapy in patients with presacral ganglioneuroma. (erdogan.edu.tr)
- Brock CL, Brock CL, Sharma A, Villada FA, Schubert J. Mediastinal ganglioneuroma with osseous invasion simulating malignant transformation of osteochondroma on CT imaging. (creighton.edu)
Tumor2
- Ganglioneuroma is a tumor of the autonomic nervous system. (medlineplus.gov)
- The evolution, after six years of stopping treatment, was marked by the maturation of its tumor into a ganglioneuroma. (lupinepublishers.com)
Sympathetic nervou1
- Ganglioneuroma is a rare benign neoplasm of the sympathetic nervous system. (auanet.org)
Noncancerous2
- citation needed] Most ganglioneuromas are noncancerous, thus expected outcome is usually good. (wikipedia.org)
- Most ganglioneuromas are noncancerous. (medlineplus.gov)
Neuroblastomas1
- These cells are believed to be the precursors of neuroblastomas and ganglioneuromas. (medscape.com)
Surgical1
- Complete surgical resection of ganglioneuromas is important, because it allows for good tissue sampling and a thorough pathology examination of the specimen to ensure a correct diagnosis of ganglioneuroma. (medscape.com)
Diagnosis2
- however, the diagnosis of ganglioneuroma cannot be based on radiologic findings alone. (medscape.com)
- Ultrasound and CT imaging may suggest the diagnosis while MRI findings can be specific for Ganglioneuroma. (auanet.org)
Asymptomatic1
- A ganglioneuroma is typically asymptomatic, and is typically only discovered when being examined or treated for another condition. (wikipedia.org)
Immunohistochemical2
- Fine-needle endoscopic ultrasound-guided core biopsy revealed characteristic histopathology of ganglioneuroma, as confirmed by immunohistochemical positivity for S100, SOX-10, and synaptophysin. (beaumont.org)
- Ganglioneuroma was diagnosed using immunohistochemical analysis . (bvsalud.org)
Occur2
- Ganglioneuromas usually occur in people over 10 years of age. (medlineplus.gov)
- Pancreatic ganglioneuromas occur mostly in children and rarely in young adults, with no cases reported in adults older than 60 years. (beaumont.org)
Imaging2
- Magnetic resonance imaging (MRI) and computed tomography (CT) scanning are the preferred methods for imaging ganglioneuromas and ganglioneuroblastomas. (medscape.com)
- Therefore it is imperative that, in work-up of adrenal incidentalomas, other less common aetiologies such as ganglioneuroma should be considered, and the latter should be suspected in adrenal mass on imaging without associated hormone hyper production. (journalcra.com)
Citation1
- citation needed] Ganglioneuromas can be diagnosed visually by a CT scan, MRI scan, or an ultrasound of the head, abdomen, or pelvis. (wikipedia.org)
Patients1
- Because ganglioneuromas are benign, treatment may not be necessary, as it would expose patients to more risk than leaving it alone. (wikipedia.org)
Tissue2
- Pathologically, ganglioneuromas are composed of ganglion cells, Schwann cells and fibrous tissue. (wikipedia.org)
- Ganglioneuromas often present as a solitary, painless, slow-growing mass consisting of ganglion cells, Schwann cells, and fibrous tissue. (medscape.com)
Found1
- We describe the case of an incidentally found ganglioneuroma in a woman. (auanet.org)
Images1
- T1-weighted magnetic resonance images of a ganglioneuroma. (medscape.com)
Appearance1
- Grossly, ganglioneuroma may have a trabecular or whorled appearance resembling a leiomyoma. (webpathology.com)
Retroperitoneal10
- Presentation of 2 cases of retroperitoneal ganglioneuroma (paravertebral and adrenal, respectively), accidentally diagnosed during ultrasound study. (cun.es)
- Retroperitoneal ganglioneuroma with nodal involvement in an adult patient with human immunodeficiency virus: a case report and review of the literature. (escholarship.org)
- We present a rare case of a retroperitoneal ganglioneuroma found in a human immunodeficiency virus positive adult, which was complicated by lymph node involvement. (escholarship.org)
- A case of ganglioneuroma presenting as a retroperitoneal mass in a 5-yr-old girl was diagnosed by preoperative fine-needle aspiration cytology. (lookfordiagnosis.com)
- 11. Total laparoscopic excision of retroperitoneal ganglioneuroma using the hanging method and a vessel-sealing device. (nih.gov)
- 12. Robotic and standard surgical intervention as adjunct therapies for retroperitoneal ganglioneuroma resection: a case report. (nih.gov)
- 15. Retroperitoneoscopic resection of retroperitoneal nonadrenal ganglioneuromas: our technique and clinical outcomes. (nih.gov)
- 17. Retroperitoneal ganglioneuroma mimicking right adrenal mass. (nih.gov)
- 18. Retroperitoneal ganglioneuroma encasing the celiac and superior mesenteric arteries. (nih.gov)
- 20. Retroperitoneal ganglioneuroma in childhood--a presentation of two cases. (nih.gov)
Benign ganglioneuroma1
- It is diagnosed during infancy and shows notable heterogeneity with regard to both histology and clinical behavior [ 2 , 3 ], ranging from rapid progression associated with metastatic spread and poor clinical outcome to spontaneous, or therapy-induced, regression into benign ganglioneuroma [ 4 ]. (biomedcentral.com)
Dumbbell Ganglioneuroma2
- 8. Giant Thoracolumbar Dumbbell Ganglioneuroma. (nih.gov)
- Cervical dumbbell ganglioneuroma producing spinal cord compression. (alfamedica.rs)
Ganglioneuroblastomas2
- Magnetic resonance imaging (MRI) and computed tomography (CT) scanning are the preferred methods for imaging ganglioneuromas and ganglioneuroblastomas. (medscape.com)
- ganglioneuromas, and ganglioneuroblastomas. (nih.gov)
Paravertebral1
- 9. Thoracolumbar paravertebral giant ganglioneuroma and scoliosis: a case report and literature review. (nih.gov)
Resection2
- Standard therapy includes en-bloc resection, with accompanying radiation therapy (RT) and chemotherapy if complete resection is not possible. (medscape.com)
- 1. Retroperitoneoscopic resection of a T11-L2 right-sided ganglioneuroma. (nih.gov)
Ganglion cells2
- Pathologically, ganglioneuromas are composed of ganglion cells, Schwann cells and fibrous tissue. (wikipedia.org)
- Ganglioneuromas often present as a solitary, painless, slow-growing mass consisting of ganglion cells, Schwann cells, and fibrous tissue. (medscape.com)
Spinal2
Adrenal masses1
- We estimated the dual-phase enhanced CT findings of 258 adrenal masses (42 ganglioneuromas, 216 lipid-poor adenomas) in 258 patients from July 2008 to July 2020 with ganglioneuromas and July 2016 to July 2020 with lipid-poor adenomas. (springeropen.com)
Cervical2
- However, ganglioneuromas of the cervical spine with intradural extension and multiple locations are extremely rare. (nih.gov)
- We describe a 32-year-old woman with multiple ganglioneuromas of the cervical, dorsal and lumbar spine associated with a few café-au-lait spots and subcutaneous nodules. (nih.gov)
Symptoms1
- A ganglioneuroma usually causes no symptoms. (medlineplus.gov)
Tumours1
- Ganglioneuromas are solid, firm tumours that typically are white when seen with the naked eye. (wikipedia.org)
Scan1
- citation needed] Ganglioneuromas can be diagnosed visually by a CT scan, MRI scan, or an ultrasound of the head, abdomen, or pelvis. (wikipedia.org)
Findings1
- We aimed to retrospectively compare dual-phase enhanced CT findings which were helpful in distinguishing adrenal ganglioneuromas from adrenal lipid-poor adenomas. (springeropen.com)
Rare1
- In particular, when adrenal incidentalomas are detected, it is still a challenge for radiologists to distinguish adrenal ganglioneuromas from adrenal lipid-poor adenomas due to our rare knowledge of adrenal ganglioneuromas [ 6 ]. (springeropen.com)
Typically2
- A ganglioneuroma is typically asymptomatic, and is typically only discovered when being examined or treated for another condition. (wikipedia.org)
- Ganglioneuromas are typically singular in nature, but rarely can present with lymph node involvement and distant metastasis. (escholarship.org)
Nerve1
- 19. Microsurgical excision of ganglioneuroma arising from the C8 nerve root within the neuroforamen. (nih.gov)
Rarely1
- Ganglioneuromas may be present as an isolated finding and, rarely, in association with neurofibromatosis type 1 (NF1). (nih.gov)
Good1
- lots of info, some good news also, the swollen lymph node turned out to be a ganglioneuroma, nothing to do with the cancer. (cancer.org)
Case report3
Spread2
- A ganglioneuroma may become cancerous and spread to other areas. (medlineplus.gov)
- Pathology results revealed metastatic spread of ganglioneuroma to surrounding lymph nodes. (escholarship.org)