Loading...
  • critical
  • While the firing patterns of septal neurons enable the MS/DBB to generate rhythmic output critical for the generation of the hippocampal theta rhythm, the ability to synchronize these action potentials is dependent on the interconnectivity between the three major MS/DBB neuronal populations. (diva-portal.org)
  • classes of GABAergic drugs
  • While the majority of GABAA receptors (those containing α1-, α2-, α3-, or α5-subunits) are benzodiazepine sensitive, there exists a minority of GABAA receptors (α4- or α6-subunit containing) which are insensitive to classical 1,4-benzodiazepines, but instead are sensitive to other classes of GABAergic drugs such as neurosteroids and alcohol. (wikipedia.org)
  • cortical neurons
  • In order to clarify potential trophic interactions between cortical neurons and cholinergic projections, we used double-fluorescent immunohistochemistry to classify NGF-expressing cells in several cortical regions, including the prefrontal cortex, primary motor cortex, parietal cortex and temporal cortex. (frontiersin.org)
  • Whereas some studies suggested that OPCs can generate cortical neurons, other studies rejected these findings. (wikipedia.org)
  • cholinergic neurons
  • Within the cortex, nerve growth factor (NGF) mediates the innervation of cholinergic neurons during development, maintains cholinergic corticopetal projections during adulthood and modulates cholinergic function through phenotypic control of the cholinergic gene locus. (frontiersin.org)
  • neuronal cell
  • Electrophysiological studies on neurons and neuronal cell lines indicate that stimulation of the 5-HT 3 R causes a rapid depolarization produced by an increased membrane permeability to monovalent cations ( Peters and Lambert, 1989 ). (jneurosci.org)
  • synaptic
  • Synaptic communication between neurons leads to the establishment of functional neural circuits that mediate sensory and motor processing, and underlie behavior. (wikipedia.org)
  • Spinal Cord
  • dILA neurons in the dorsal spinal cord are the product of terminal and non-terminal asymmetric progenitor cell divisions, and require Mash1 for their development," Development , vol. 133, no. 11, pp. 2105-2113, 2006. (hindawi.com)
  • 1994
  • Regions in the human brain Gioia, Magda (1994), A cluster analysis of the neurons of the rat interpeduncular nucleus, University of Milan, Italy: Wiley-Blackwell Cajal, S.R. (1909,1911,1995). (wikipedia.org)
  • pyramidal
  • Classification of cells producing NGF in the cortex is lacking, however, and cholinergic corticopetal projections have been shown to innervate both pyramidal and GABAergic neurons in the cortex. (frontiersin.org)
  • projections
  • We found that these neurons send widespread projections to wakefulness-related areas in the hypothalamus and brain stem, including the LHA where these fibers make close appositions to orexin neurons. (frontiersin.org)
  • forebrain
  • Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain. (vanderbilt.edu)
  • In an effort to identify genes that specify the mammalian forebrain, we used a comparative approach to identify mouse homologs of transcription factors expressed in developing Caenorhabditis elegans GABAergic neurons. (vanderbilt.edu)
  • Specification
  • A nonclassical bHLH-Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling," Genes and Development , vol. 22, no. 2, pp. 166-178, 2008. (hindawi.com)
  • functional
  • It is important to know the anatomical and functional interactions between the POA sleep-active neurons and orexin neurons, both of which play important, but opposite roles in regulation of sleep/wakefulness states. (frontiersin.org)
  • To obtain information on the functional significance of the 5-HT 3 R-containing neurons, we sought to determine additional neurochemical features of the neurons that express this receptor in the telencephalon. (jneurosci.org)
  • They noted that CR-50 reacted specifically with Cajal-Retzius neurons, whose functional role was unknown until then. (wikipedia.org)
  • cells
  • However, these studies are not genetically targeted to specific neuron types, and so the cells that are responsible remain to be clarified. (frontiersin.org)
  • We examined the role of the projection from GABAergic neurons in the POA to the orexin neurons in the LHA in inhibiting the latter cells, and the effect of activating this pathway on sleep. (frontiersin.org)
  • Our results show that NGF colocalizes extensively with GABAergic cell markers in all cortical regions examined, with >91% of NGF-labeled cells coexpressing GAD65/67. (frontiersin.org)
  • These data suggest that catfish red cone horizontal cells are GABAergic. (mysciencework.com)
  • Other common methods include tissue culture studies of neurons, genome-wide analysis of non-brain cells in living patients (see PBMC), and transgenic and schizophrenic animal models. (wikipedia.org)
  • The neuroblasts are the cells that undergo mitotic division and produce neurons. (wikipedia.org)
  • The PIR neurons cluster together creating "densely terminating afferent fibers…forming a core imposed on a diffuse background matrix of PIR cells" (Jones 2001). (wikipedia.org)
  • signals
  • As a mouse begins to explore its environment by actively moving its whiskers, motor-related signals drive different activity patterns in specific types of GABAergic neurons, thereby promoting sensorimotor integration. (epfl.ch)
  • dorsal
  • Here we show that GABAergic neurons gating PS (PS-off neurons) are principally located in the ventrolateral periaqueductal gray (vlPAG) and the dorsal part of the deep mesencephalic reticular nucleus immediately ventral to it (dDpMe). (nih.gov)
  • cortex
  • Membrane potential recordings from these genetically defined GABAergic neurons in layers 2 and 3 of mouse barrel cortex reveal that they are differentially modulated by whisker behavior. (epfl.ch)
  • neural
  • Maturation of the GABAergic transmission in normal and pathologic motoneurons," Neural Plasticity , vol. 2011, Article ID 905624, 2011. (hindawi.com)
  • The neural circuit mechanisms underlying such cell-type specific activity of GABAergic neurons are now being unraveled. (epfl.ch)
  • The results demonstrate that the inhibitory neural system is established very early during the development of the crayfish embryo and supports the hypothesis that inhibitory neurons may play an important role in controlling the development of other neural systems which mature later. (edu.au)
  • exhibit
  • GAD-GFP neurons invariably failed to exhibit the potassium-mediated slow depolarizing potential during injection of positive current that was present in all non-GFP neurons. (biomedsearch.com)