Flaviviridae infections. Medical search. Frequent questions

A genus of virus in the family FLAVIVIRIDAE. (bvsalud.org)
Equine arboviral encephalomyelitis is due to infection with arthropod-borne viruses typically belonging to the families Togaviridae (genus Alphavirus ) or Flaviviridae (genus Flavivirus ). (msdvetmanual.com)
Z ported human infections indicated that clinical characteris- ika virus (ZIKV) is a mosquito-transmitted virus in the tics of infection with ZIKV included fever, headache, mal- family Flaviviridae and genus Flavivirus . (folkhalsomyndigheten.se)
Zika virus(ZIKV) belongs to the family Flaviviridae and genus Flavivirus. (bvsalud.org)

Infections with viruses of the family FLAVIVIRIDAE. (uams.edu)
They found that the molecule treatment significantly limited replication of the viruses as well as infection in cells. (yale.edu)
Our report shows, for the first time, that we can use a small-molecule inhibitor to block infection by the flaviviridae family of viruses," Contessa said. (yale.edu)
Infectious hepatitis can be caused by any one of the five unrelated hepatitis viruses, A, B, C, D, or E. These are the viruses that cause liver diseases of the same names, and most cases of hepatitis are caused by viral infection. (coursehero.com)
The hepatitis A and E viruses typically cause an acute infection, hepatitis B and C can cause chronic or acute infections, and hepatitis D causes chronic infection in patients already infected with hepatitis B. Acute hepatitis typically clears on its own within a few weeks, without the need for medical intervention. (coursehero.com)
When the Zika epidemic spread through the American continent and then later to Africa and Asia in 2015, researchers compared the characteristics of the Zika infection to Dengue, considering both these viruses were transmitted primarily through the same vector, the Aedes aegypti female mosquitoes. (frontiersin.org)
Together, this information appraises the current understanding of both Zika and Dengue infections, providing insights for future vaccine design approaches against both viruses. (frontiersin.org)
Proposals are described for the assignment of recently reported viruses, infecting rodents, bats and other mammalian species, to new species within the Hepacivirus and Pegivirus genera (family Flaviviridae). (ox.ac.uk)
there is overlap between the two genera in the type of internal ribosomal entry site and the presence of miR-122 sites in the 5' UTR, the predicted number of N-linked glycosylation sites in the envelope E1 and E2 proteins, the presence of poly U tracts in the 3' UTR and the propensity of viruses to establish a persistent infection. (ox.ac.uk)
Hantavirus Infection Hantaviridae are a family of enveloped single-stranded RNA viruses, which consists of at least 4 serotypes with 9 viruses causing 2 major, sometimes overlapping, clinical syndromes: Hemorrhagic. (msdmanuals.com)
Viruses establish systemic infection and viremia. (slideshare.net)
Viruses are good inducers of interferon, which can account for the flulike symptoms of infection. (slideshare.net)
These febrile diseases result from infection by viruses from 4 viral families: Arenaviridae, Bunyaviridae, Filoviridae, and Flaviviridae. (medscape.com)
Viruses belonging to the family Flaviviridae is a major public health problem worldwide including India. (ibab.ac.in)

The reported occurrences of ZIKV infections are thought to be transmitted mainly by the mosquito species Aedes aegypti and Aedes albopictus . (frontiersin.org)
Using the Aedes -dengue virus infection model, we aim to identify key factors controlling virus multiplication in the mosquito using genome wide approaches and characterize their function using gene editing technologies. (ibab.ac.in)
The four serotypes of dengue virus (DENV) (family Flaviviridae ) are transmitted from infected to susceptible humans primarily by Aedes mosquitoes. (who.int)

It is an arthropod-borne virus (arbovirus) within the family Flaviviridae class. (amrita.edu)
Dengue infection is caused by the dengue virus that belongs to the family Flaviviridae . (mims.com)
The present invention is relative to chimerical peptides, whose primary structure holds at least one segment which inhibits the activation of the NS3 protease of a virus from the Flaviviridae family, they also contain a cell penetrating segment and they are capable of inhibiting or attenuate the viral infection. (patentsencyclopedia.com)
This invention is also relative to pharmaceutical compounds which contain these chimerical peptides for the prevention and/or treatment of the infection caused by a virus of the Flaviviridae family. (patentsencyclopedia.com)
1. Chimerical peptides, characterized by having a primary structure comprising at least one segment inhibitor of the activation of the NS3pro protease from a virus of the Flaviviridae family and a cell penetrating segment and these peptides are able to inhibit or attenuate the infection by the virus. (patentsencyclopedia.com)
10. Chimerical peptides according to the claim 1, where the mentioned virus from the Flaviviridae family is a Hepacivirus and specifically HCV. (patentsencyclopedia.com)
Dengue virus (DENV) is an enveloped, single-stranded RNA virus belonging to the Flaviviridae family. (frontiersin.org)
Proposed update to the taxonomy of the genera Hepacivirus and Pegivirus within the Flaviviridae family. (ox.ac.uk)
HCV is an enveloped RNA virus that belongs to the Flaviviridae family and in most instances causes chronic liver infections. (qxmd.com)
Non-primate hepacivirus (NPHV), equine pegivirus (EPgV) and Theiler's disease associated virus (TDAV) are newly discovered members of two genera in the Flaviviridae family, Hepacivirus and Pegivirus respectively, that include human hepatitis C virus (HCV) and human pegivirus (HPgV). (ox.ac.uk)
DEN-1, 2, 3 and 4) under the family Flaviviridae. (who.int)
HCV is defined as an envelope, single stranded positive sense RNA (9.5kb) affiliated with the Flaviviridae family. (rapidtest.com)
The Bovine Viral Diarrhea Virus (BVDV) is a Pestivirus in the Flaviviridae family that possesses wide distribution and is characterized by the abillity of producing persistent infection, immune cross reaction with other Pestivírus and host inespecificity. (ufrgs.br)

Urban demographic expansion, deforestation and agricultural settlements in peri-urban areas, are known causes of the increase in the probability of concurrent infection of these two diseases. (who.int)
Concurrent infections of malaria and dengue are when both the diseases occur simultaneously in an individual. (who.int)
however, the risk that these species might represent to the epidemiology of BVDV infection and other diseases justify this investigation. (ufrgs.br)
Clinical presentation of the infection is nonspecific and may often be confused with symptoms of other flaviviral diseases (dengue, West Nile [WN], and chikungunya). (bvsalud.org)

Hepatitis caused by viral infection can be a chronic or acute disease. (coursehero.com)
Inflammation of brain parenchymal tissue as a result of viral infection. (childrensmercy.org)
Recognition of viral infection by the innate immune system occurs through the cytoplasmic recognition of cellular receptors of viral nucleic acids. (medscape.com)
however, serologic testing and necropsy are required for definitive diagnosis of viral infection and subsequent encephalomyelitis. (msdvetmanual.com)
15. Thomas EA, John M, Bhatia A. Muco-Cutaneous manifstations of dengue viral infection in Punjab. (rjptonline.org)

The current scenario regarding the widespread Zika virus (ZIKV) has resulted in numerous diagnostic studies, specifically in South America and in locations where there is frequent entry of travelers returning from ZIKV-affected areas, including pregnant women with or without clinical symptoms of ZIKV infection. (frontiersin.org)
This situation has created an alarming public health emergency of international concern requiring the detection of this life-threatening viral candidate due to increased cases of newborn microcephaly associated with ZIKV infection. (frontiersin.org)
Previously, only sporadic cases of negligible concern associated with human ZIKV infection were reported ( Hayes, 2009 ). (frontiersin.org)
Recent outbreaks of ZIKV infections have become fatal on a daily basis in the Americas, where this obscure viral candidate has been placed at the forefront of global healthcare. (frontiersin.org)
Considering the calamity of ZIKV infection, there is an urgent need to develop rapid detection methods for ZIKV along with DENV, which shares common clinical symptoms with ZIKV. (frontiersin.org)
The Zika Virus (ZIKV) happens to be one of the recent infections investigated after the Ebola pandemic. (amrita.edu)
netic and serologic properties of the ZIKV associated with In 1977, ZIKV infection was confi rmed among 7 pa- this epidemic. (folkhalsomyndigheten.se)
Several ZIKV human recent fl avivirus infection in several patients. (folkhalsomyndigheten.se)

The development of animal models of dengue virus (DENV) infection and disease has been challenging, as epidemic DENV does not naturally infect non-human species. (mdpi.com)
however, a new model using high doses of DENV has recently been shown to develop hemorrhagic signs after infection. (mdpi.com)

Aunque en general los pegivirus no son patógenos, en ocasiones se asocian coinfecciones por pegivirus al LINFOMA NO HODGKINIANO en el ser humano y a una hepatitis viral, la enfermedad de Theiler, en los caballos. (bvsalud.org)

Flaviviridae ) pathogenic to humans (1). (cdc.gov)
The study demonstrates that NPHV and EPgV infections are widespread and enzootic in the study horse population and confirms that NPHV and potentially EPgV have higher frequencies of viral clearance than HCV and HPgV infections in humans. (ox.ac.uk)

Despite revised clinical classifications of dengue infections by the World Health Organization, the wide spectrum of the manifestations of dengue illness continues to pose challenges in diagnosis and patient management for clinicians. (frontiersin.org)
To investigate their epidemiology, persistence and clinical features of infection, large cohorts of horses and other mammalian species were screened for NPHV, EPgV and TDAV viraemia and for past exposure through serological assays for NPHV and EPgV-specific antibodies. (ox.ac.uk)
Since there are similarities in the clinical characteristics between these two infections, diagnosis of malaria and dengue co-infections might be either misdiagnosed or misinterpreted as mono-infections. (who.int)
The HCV Ab ELISA Test is for clinical lab diagnosis of patients who are suspected of having a hepatitis C virus infection, and for blood donor screening. (rapidtest.com)
We review the endemic and emerging alpha- and betacoronavirus infections of wildlife, livestock, and companion animals, and provide information on the receptor usage, known hosts, and clinical signs associated with each host for 15 coronaviruses discovered in people and animals. (preprints.org)
11 Directors of clinical laboratories also are mandated to notify the Ministry of Health whenever any blood sample provides evidence of recent dengue infection. (who.int)
Dengue virus infection has emerged as marker in clinical practice ( 11 ). (who.int)
Based on the clinical examination, hematological disorder due to dengue fever was chiefly considered, while differential diagnoses included oral squamous cell carcinoma of tongue and buccal mucosa and other infections like influenza, measles, rubella and bacterial sepsis. (bvsalud.org)
Both types of assays in association with the clinical presentation (jaundice, ALT elevation) have been used to adequate identify acute or chronic HCV infections. (medscape.com)

An important difference to note, however, was that the Zika epidemic diffused in a shorter time span compared to the persisting feature of Dengue infections, which is endemic in many Asian countries. (frontiersin.org)

Arboviral Infections. (slideshare.net)
Some arboviral infections can be of particular concern for pregnant women or their fetuses. (cdc.gov)

After infection the hepatitis virus can remain dormant in the infected individual for one to three months before symptoms of the disease emerge. (coursehero.com)
This review discusses similarities between Dengue and Zika infections, comparing their disease transmissions and vectors involved, and both the innate and adaptive immune responses in these infections. (frontiersin.org)
Finally, a summary of the immune biomarkers that have been reported for dengue and Zika viral infections are discussed which may be useful indicators for future anti-viral targets or predictors for disease severity. (frontiersin.org)
The disease is endemic in at least 100 countries in the tropics and subtropics with 50 - 100 million infections and 22,000 deaths yearly, causing it to be the leading cause of illness and death in these regions (Waggoner et al. (frontiersin.org)
By comparing viraemia frequencies in horses with and without liver disease, no evidence was obtained that supported an association between active NPHV and EPgV infections with hepatopathy. (ox.ac.uk)
There is evidence of BVDV infection in camelids, in which the disease is similar to that seen in cattle. (ufrgs.br)
Subsequently we will be translating this knowledge to design effective disease transmission blocking strategies for dengue and other viral infections.slating this knowledge to design effective disease transmission blocking strategies for Dengue and other viral infections. (ibab.ac.in)
Clinically-apparent disease usually occurs with the first or second infections, rarely with the third or fourth. (who.int)
We describe a reported fatal case of HRTV infection in the Maryland and Virginia region, states not widely recognized to have human HRTV disease cases. (cdc.gov)

Reoviridae Infections" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
This graph shows the total number of publications written about "Reoviridae Infections" by people in this website by year, and whether "Reoviridae Infections" was a major or minor topic of these publications. (umassmed.edu)
Below are the most recent publications written about "Reoviridae Infections" by people in Profiles. (umassmed.edu)

This 3rd generation of tests have improved sensitivity and have lessened the time period (60 days) between infection and the subsequent appearance of antibodies to HCV. (rapidtest.com)
These tests detect antibodies to HCV (anti-HCV) and are used for screening and diagnosing HCV infection. (medscape.com)

Consideration of the genetic identity of both the Dengue and Zika flaviviruses as well as the cross-reactivity of relevant T cells along with the actions of CD4+ cytotoxic cells in these infections are also presented. (frontiersin.org)
O Zika virus (ZIKAV) é um RNA vírus, do gênero Flavivírus, família Flaviviridae. (bvsalud.org)
in all cases infection appeared relatively mild, self- sus monkey during a yellow fever study in the Zika forest limiting, and nonlethal ( 6 , 8 - 10 ). (folkhalsomyndigheten.se)
Questions are limited to clinicians who would like information related to Zika virus infection. (cdc.gov)

Potential pathogenic mechanisms involved in the association between lichen planus and hepatitis C virus infection. (qxmd.com)

In 2020, because of the changing epidemiology of HCV infections in the United States, CDC expanded previous risk-based testing recommendations to include universal screening for all adults aged ≥18 years at least once and for all pregnant persons during each pregnancy ( 12 ). (cdc.gov)

M-positive test) tick-borne encephalitis infection. (cdc.gov)
Several arboviral vaccines have been licensed for many years and can be used to prevent infection in travelers, namely Japanese encephalitis, yellow fever, and tick-borne encephalitis vaccines. (cdc.gov)

The live recombinant vaccine has shown effectiveness of 97.5% in preventing infection among 90,000 individuals in an active Ebola virus outbreak in the Democratic Republic of Congo. (medscape.com)

An important concept in the evaluation of data regarding transfusion-transmitted bacterial infections (TTBIs) is the definition of a case. (medscape.com)

Malaria and dengue are endemic in similar tropical regions, and therefore, may result in the possibility of co-infection. (who.int)

These recommendations evolved from observations during the SARS epidemic that failure to implement basic source control measures with patients, visitors, and healthcare personnel with signs and symptoms of respiratory tract infection may have contributed to SARS coronavirus (SARS-CoV) transmission. (cdc.gov)
The majority of infections occur in children and are subclinical or have features limited to transient fever and gastrointestinal symptoms. (curehunter.com)
This point out the high level of co-infection with malaria amongst patients with severe symptoms who tested positive for Dengue Fever, and has implications on the approach for vector control and surveillance activities. (who.int)

With the exception of a vaccine for yellow fever and ribavirin, which is used as a drug treatment for some arenaviral infections, no cures or drug treatments for viral hemorrhagic fever exist. (medscape.com)
1. Heydari M, Metanat M, Rouzbeh-Far MA, Tabatabaei SM, Rakhshani M, Sepehri-Rad N, Keshtkar-Jahromi M. Dengue fever as an emerging infection in southeast Iran. (rjptonline.org)
A reduction in platelet number or function can occur through a variety of mechanisms, including autoimmune destruction, spleen sequestration, bone marrow infiltration by tumor cells, infection (e.g. dengue fever), and adverse drug reaction. (bvsalud.org)

Search for substances that could effectively inhibit this type of infections is now a priority. (saratoga.com)

Invasive fungal infections, particularly those caused by Candida species, are common in hospitalized, immunocompromised, or critically ill patients and are associated with considerable morbidity and mortality. (mims.com)

During 2010-2021, hepatitis C virus (HCV) acute and chronic infections (hereinafter referred to as HCV infections) increased in the United States, consequences of which include cirrhosis, liver cancer, and death. (cdc.gov)
Rates of acute infections more than tripled among reproductive-aged persons during this time (from 0.8 to 2.5 per 100,000 population among persons aged 20-29 years and from 0.6 to 3.5 among persons aged 30-39 years). (cdc.gov)
Because acute HCV infection can lead to chronic infection, this has resulted in increasing rates of HCV infections during pregnancy. (cdc.gov)
Rates of HCV acute and chronic infections (referred hereinafter as HCV infections) have been steadily increasing in the United States since 2010, with rates of acute infections more than tripling among reproductive-aged persons as of 2021, from 0.8 to 2.5 per 100,000 population among persons aged 20-29 years and from 0.6 to 3.5 among persons aged 30-39 years ( 4 , 5 ). (cdc.gov)
As a result of increasing rates of acute infections in reproductive-aged persons and subsequent chronic infections, overall rates of HCV infections during pregnancy have increased by 20% during 2016-2020 and up to tenfold during 2000-2019 ( 6 , 7 ). (cdc.gov)
After an acute HCV infection, HCV RNA could be detectable in serum within 2 weeks following exposure. (medscape.com)
Both test results are positive in case of acute or chronic infection. (medscape.com)
On the other hand, HCV RNA results can be positive with negative anti-HCV findings in cases of early stages of acute infection, false positive results, or chronic infection in an immunosuppressed individual. (medscape.com)

Studies have estimated that chronic HCV infection will develop in 5.8%-7.2% of all perinatally exposed (i.e., exposed during pregnancy or delivery) infants and children ( 13 , 14 ), and curative direct-acting antiviral (DAA) therapy can be administered beginning at age 3 years ( 15 , 16 ). (cdc.gov)
A negative test is sufficient to exclude a diagnosis of chronic HCV infection in immune-competent patients. (medscape.com)

It is important, however, to differentiate between the two conditions, as malaria is treatable and any delay in treatment may result in a poor outcome The reported frequencies of concurrent infection in febrile patients presenting to outpatient departments of hospitals in various studies have been quite variable and range from 1% in French Guiana2 to 6% in India3 and 27% in Pakistan. (who.int)

HCV is now accepted as the major agent for non-A and non-B hepatitis transfusion infection. (rapidtest.com)

Seroprevalence studies conducted in the three largest outbreak clusters revealed that 73.2% of residents with recent infection were asymptomatic. (who.int)

DRUG RESISTANCE: There are no known antiviral treatments available for human infections. (saratoga.com)

With an estimated 50 million infections annually, 3 the burden of dengue is a heavy one indeed, 4 especially to countries in the Asia Pacific region. (who.int)

The geographic distribu- tion of the infection is uneven, with most illnesses occur- ring in the Siberian and Ural regions. (cdc.gov)
this may also occur after recovery from infection or following spontaneous resolution of HCV infection. (medscape.com)

The team plans to develop the molecule into a drug to treat the viral infections, which don't currently have any approved antiviral therapy. (yale.edu)

We found that the TBEV strains that most likely caused the infection with hemorrhagic syndrome also carry unique mutations in protein E and Vladimir A. Ternovoi,* Gennady P. Kurzhukov, belong to the Far Eastern genomic subtype. (cdc.gov)

Organisms19

Diseases8

Chemicals and Drugs8

Phenomena and Processes4

Information Science2

Health Care2

Genus4

Viruses14

Aedes3

Family13

Diseases4

Viral infection5

ZIKV8

DENV2

Pegivirus1

Humans2

Clinical9

Dengue infections1

Arboviral Infections2

Disease9

Reoviridae3

Antibodies2

Zika4

Hepatitis C virus infecti1

Epidemiology1

Tick-borne enceph2

Ebola1

Bacterial1

Endemic1

Symptoms3

Fever3

Inhibit1

Species1

Acute8

Chronic HCV infection2

Febrile1

Transfusion1

Asymptomatic1

Human infections1

Million infections1

Occur2

Antiviral therapy1

Hemorrhagic1