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  • dysfunction
  • During the past years possible side effects have been described in several countries encompassing a collection of symptoms consistent with pronounced autonomic dysfunction coupled with severe non-migraine-like headache, excessive fatigue, cognitive dysfunction, gastrointestinal discomfort and widespread pain of a neuropathic character. (sanevax.org)
  • muscle fatigue
  • Muscle fatigue, for example, results when the contractile properties of muscle are reduced, and continued exertion is impossible unless the muscle is allowed to rest. (infoplease.com)
  • In muscle tissue, the depletion of glycogen (stored glucose), a source of energy for muscle cells, and the accumulation of lactic acid , which is produced through the breakdown of glucose, was long thought to the cause of muscle fatigue, but it is now known that the lactic acid produced is used as an energy source as well. (infoplease.com)
  • A new explanation of muscle fatigue suggests that it is related to the control of the flow of the calcium ions in muscle. (infoplease.com)
  • World-renowned muscle fatigue researchers, Roger Enoka and Doug Stuart (1992), describe fatigue as an over-all concept intended to symbolize an acute impairment of performance that includes both an increase in perceived effort necessary to exert a desired force and an eventual inability to produce this force. (unm.edu)
  • The main area of muscle fatigue difference in men and women is in the contractile mechanisms of muscle (Hunter, 2016). (unm.edu)
  • On several occasions I have had a rush of muscle fatigue. (medhelp.org)
  • muscle fatigue- does it come and go? (medhelp.org)
  • i'm noticing a major increase in muscle fatigue. (medhelp.org)
  • Physical fatigue, or muscle fatigue, is the temporary physical inability of a muscle to perform optimally. (wikipedia.org)
  • The onset of muscle fatigue during physical activity is gradual, and depends upon an individual's level of physical fitness, and also upon other factors, such as sleep deprivation and overall health. (wikipedia.org)
  • International Civil Aviati
  • The International Civil Aviation Organization (ICAO) defines fatigue as "A physiological state of reduced mental or physical performance capability resulting from sleep loss or extended wakefulness, circadian phase, or workload. (wikipedia.org)
  • The International Civil Aviation Organization (ICAO) that codifies standards and regulations for international air-navigation defines fatigue as: "A physiological state of reduced mental or physical performance capability resulting from sleep loss or extended wakefulness, circadian phase, or workload (mental and/or physical activity) that can impair a crew member's alertness and ability to safely operate an aircraft or perform safety related duties. (wikipedia.org)
  • Physiological
  • Physiological processes that contribute to fatigue are grouped into two categories: 1) Central, which is muscle activation signaling from the brain, and 2) Peripheral, which are the physiological mechanisms occurring at the neuromuscular junction and within the contracting muscle. (unm.edu)
  • These glutamate autoreceptors are able to inhibit synaptic fatigue in order to prevent the detrimental physiological consequences that could result from dysfunctional blood pressure regulation in the aorta (not true) When synaptic vesicles release neurotransmitters into the synapse that bind with post-synaptic membrane proteins to pass a signal, neurotransmitter re-uptake occurs to recycle neurotransmitters in the presynaptic cell in order to be released again. (wikipedia.org)
  • apathy
  • AIDS fatigue, when public health messages are ignored for similar reasons Information fatigue Voter fatigue, voting apathy related to too-frequent elections S.E. Smith. (wikipedia.org)
  • In politics, voter fatigue is the apathy that the electorate can experience under certain circumstances, one of which could be (in exceptional circumstances) that they are required to vote too often, or that they feel disengaged. (wikipedia.org)
  • Voter fatigue and voter apathy should be distinguished from what arises when voters are not allowed or unable to vote, or when disenfranchisement occurs, or voters are engaged generally but repelled by the options available. (wikipedia.org)
  • phenomenon
  • Condom fatigue is a term used by medical professionals and safer sex educators to refer to the phenomenon of decreased condom use. (wikipedia.org)
  • Condom fatigue is not a universal phenomenon. (wikipedia.org)
  • As a common phenomenon, static fatigue is manifested in many kinds of embrittlement, of which the mechanisms are closely related to the nucleation and growth of cracks. (wikipedia.org)
  • For different exposure times in air, the static fatigue is temperature dependence, indicating kinetic considerations can be taken to explain the phenomenon. (wikipedia.org)
  • AIDS fatigue is a phenomenon wherein individuals or societies who had been concerned about the impact of HIV or AIDS become desensitized to the having a strong emotional response to HIV issues after receiving continual messages about the danger over a long period of time. (wikipedia.org)
  • Since corrosion-fatigue cracks initiate at a metal's surface, surface treatments like plating, cladding, nitriding and shot peening were found to improve the materials' resistance to this phenomenon. (wikipedia.org)
  • It has also been hypothesized that synaptic fatigue could be a result of postsynaptic receptor desensitization or changes in postsynaptic passive conductance, but recent evidence has suggested that it is primarily a presynaptic phenomenon. (wikipedia.org)
  • The existence and observations of synaptic fatigue are accepted universally, although the exact mechanisms underlying the phenomenon are not completely understood. (wikipedia.org)
  • anemia
  • One of the main symptoms of anemia is fatigue. (healthline.com)
  • In some instances this abnormal fatigue may be associated with systemic disorders such as anemia, a deficiency of protein or oxygen in the blood, addiction to drugs, increased or decreased function of the endocrine glands, or kidney disease in which there is a large accumulation of waste products. (infoplease.com)
  • As a result, cancer treatments can induce anemia which can cause fatigue. (nccn.org)
  • Treatment of anemia with erythropoietin may help decrease fatigue. (nccn.org)
  • At the end of life, fatigue is usually associated with other symptoms, especially anemia, side effects from many medications and previous treatments, and poor nutritional status. (wikipedia.org)
  • If the fatigue is caused or exacerbated by a specific medical condition, such as anemia, then treatment of that medical condition should reduce the fatigue. (wikipedia.org)
  • Anemia: Loss of oxygen-carrying red blood cells is a common cause of fatigue. (wikipedia.org)
  • inability
  • fatigue, in physiology, inability to perform reasonable and necessary physical or mental activity. (infoplease.com)
  • Symptoms associated with fatigue include slower reaction times, difficulty concentrating on tasks resulting in procedural mistakes, lapses in attention, inability to anticipate events, higher toleration for risk, forgetfulness, and reduced decision-making ability. (wikipedia.org)
  • Physical fatigue is the transient inability of a muscle to maintain optimal physical performance, and is made more severe by intense physical exercise. (wikipedia.org)
  • Mental fatigue is a temporary inability to maintain optimal cognitive performance. (wikipedia.org)
  • Olfactory fatigue, also known as odor fatigue or olfactory adaptation, is the temporary, normal inability to distinguish a particular odor after a prolonged exposure to that airborne compound. (wikipedia.org)
  • Synaptic fatigue, or short-term synaptic depression, is an activity-dependent form of short term synaptic plasticity that results in the temporary inability of neurons to fire and therefore transmit an input signal. (wikipedia.org)
  • Some cells like aortic baroreceptor neurons could have devastating effects including the inability to regulate aortic blood pressure if the onset of synaptic fatigue were to affect them. (wikipedia.org)
  • one's
  • Regular, mild to moderate exercise can boost energy levels, elevate one's mood, and lessen the feeling of fatigue. (bccancer.bc.ca)
  • At its worst, cancer-related fatigue is a draining, ongoing exhaustion that limits one's ability to enjoy life and do activities. (nccn.org)
  • Another commonly believed way to reduce olfactory fatigue is to smell one's own unperfumed skin (typically the crook of the elbow) on the theory this is the "baseline" smell for each individual. (wikipedia.org)
  • AIDS
  • Experts attribute this to "AIDS fatigue" among younger people who have no memory of the worst phase of the epidemic in the 1980s and early 1990s, as well as "condom fatigue" among those who have grown tired of and disillusioned with the unrelenting safer sex message. (wikipedia.org)
  • defines fatigue
  • The American Society for Testing and Materials defines fatigue life, Nf, as the number of stress cycles of a specified character that a specimen sustains before failure of a specified nature occurs. (wikipedia.org)
  • Condom
  • Condom fatigue has been partially blamed for an increase in HIV infection rates, though this has not been substantiated in any study. (wikipedia.org)
  • endurance
  • More research in this area will eventually elucidate new and difference recovery strategies for men and women after fatiguing endurance exercise (Hunter). (unm.edu)
  • For some materials, notably steel and titanium, there is a theoretical value for stress amplitude below which the material will not fail for any number of cycles, called a fatigue limit, endurance limit, or fatigue strength. (wikipedia.org)
  • muscles
  • The evidence of ROS having a causal influence to fatigue has been shown in small muscles, at the neuromuscular junction and in whole-body exercise (like running) by elite athletes (Reid). (unm.edu)
  • mechanisms
  • Proposed mechanisms by which cancer can cause fatigue include an increase in pro-inflammatory cytokines, dysregulation of the hypothalamic-pituitary-adrenal axis, disruption of circadian rhythms, muscle loss and cancer wasting, and genetic problems. (wikipedia.org)
  • What are the Mechanisms for Sex Differences in Fatigue? (unm.edu)
  • exhaustion
  • If excessive fatigue occurs over a prolonged period, exhaustion (marked loss of vital and nervous power) may result. (infoplease.com)
  • The disease is characterized by six months of incapacitating fatigue experienced as profound exhaustion and extremely poor stamina, and problems with concentration and short-term memory. (dailystrength.org)
  • 2016
  • Dr. Sandra Hunter (2016) explains that every human cell has a sex (defined by the chromosome complement of XX in men and XY in women) that influences fatigue in women and men differently. (unm.edu)
  • tasks
  • Hunter summarizes that women are less fatigable then men during isometric fatiguing tasks for several muscle groups. (unm.edu)
  • Without proper amount of sleep, it will feel like certain tasks seem complicated, concentration will drop and ultimately result in fatal mistakes The Federal Motor Carrier Safety Administration identifies three main factors in driver fatigue: Circadian rhythm effects, sleep deprivation and cumulative fatigue effects, and industrial or "time-on-task" fatigue. (wikipedia.org)
  • people
  • People receiving radiation therapy, by contrast, often find their fatigue steadily increases until the end of treatment. (wikipedia.org)
  • Fatigue is common in people with cancer, but it's different for each person. (cancer.org)
  • People looking for answers as to the source of their fatigue too often leave their doctors office rejected and disappointed. (tradebit.com)
  • Decision fatigue helps explain why ordinarily sensible people. (wikipedia.org)
  • Dean Spears of Princeton University has argued that decision fatigue caused by the constant need to make financial trade-offs is a major factor in trapping people in poverty. (wikipedia.org)
  • circadian
  • These factors can occur together to produce a combination of sleep deprivation, circadian rhythm effects, and 'time-on task' fatigue. (wikipedia.org)
  • corrosive
  • Corrosion fatigue is fatigue in a corrosive environment. (wikipedia.org)
  • The effects of corrosive environments on the fatigue behavior of metals were studied as early as 1930. (wikipedia.org)
  • Curves B and C represent the fatigue behavior of the same material in two corrosive environments. (wikipedia.org)
  • However, the presence of a corrosive environment during fatigue loading eliminates this stress advantage, since the fatigue limit becomes almost insensitive to the strength level for a particular group of alloys. (wikipedia.org)
  • This effect is schematically shown for several steels in the diagram on the left, which illustrates the debilitating effect of a corrosive environment on the functionality of high-strength materials under fatigue. (wikipedia.org)
  • Voter
  • Voter fatigue can be used as a criticism of the direct democracy system, in those specific situations in which voters are constantly asked to decide on policy via referenda (though it should be borne in mind that such situations may be practically rare) or an out-of-cycle recall election. (wikipedia.org)
  • However, proponents often counter that voter fatigue may be lessened by direct democracy as voters will feel their vote has more effect. (wikipedia.org)
  • Voter fatigue can cause notoriously low voter turnout rates, and potentially more protest vote, and supposedly occurs for a variety of reasons: voters are not interested in the issue. (wikipedia.org)
  • Amongst the methods that can be used to combat voter fatigue are: Making it mandatory to vote, as e.g. in Australia, Belgium or Brazil. (wikipedia.org)
  • occurs
  • Alarm fatigue or alert fatigue occurs when one is exposed to a large number of frequent alarms (alerts) and consequently becomes desensitized to them. (wikipedia.org)
  • Alarm fatigue occurs in many industries, including construction and mining (where backup alarms sound so frequently that they often become senseless background noise), healthcare (where electronic monitors tracking clinical information such as vital signs and blood glucose sound alarms so frequently, and often for such minor reasons, that they lose the urgency and attention-grabbing power which they are intended to have), and the nuclear power industry. (wikipedia.org)
  • Fatigue occurs when a material is subjected to repeated loading and unloading. (wikipedia.org)
  • often
  • The amount of fatigue, how often is happens, and how long it lasts can be different for each person. (bccancer.bc.ca)
  • A decreased attention span and difficulty understanding and thinking are often associated with fatigue. (bccancer.bc.ca)
  • Fatigue often lessens or stops when treatment ends, but sometimes it lingers. (nccn.org)
  • Symptoms of CFS often develop suddenly and include a strong, noticeable fatigue that comes and goes or remains for months. (kidshealth.org)
  • Fatigue is often caused by more than one problem. (cancer.org)
  • Fatigue is a process that has a degree of randomness (stochastic), often showing considerable scatter even in seemingly identical sample in well controlled environments. (wikipedia.org)
  • It is often manifested by static fatigue. (wikipedia.org)
  • In this scenario, the static fatigue often depends on the presence of initial flaws. (wikipedia.org)
  • fracture
  • Engineers have used any of three methods to determine the fatigue life of a material: the stress-life method, the strain-life method, and the linear-elastic fracture mechanics method. (wikipedia.org)
  • Static fatigue describes the fracture happening at a stress level less than the value required to cause ordinary tensile fracture. (wikipedia.org)
  • For example, as shown in Figure 1, in a test of the static fatigue of a 2024 aluminum coated with mercury, the alloy is subject to a stress level less than the value causing plastic flow, and the time it takes to fracture is measured. (wikipedia.org)
  • Usually a stress called static fatigue limit is present, representing the boundary below which the material does not fracture, no matter how long the test duration is. (wikipedia.org)
  • For this reason, emphasis is given to crack-propagation velocity measurements (using fracture mechanics) to study corrosion fatigue. (wikipedia.org)
  • Since fatigue crack grows in a stable fashion below the critical stress-intensity factor for fracture (fracture toughness), the process is called sub-critical crack growth. (wikipedia.org)
  • deprivation
  • Sleep deprivation and cumulative fatigue effects describe how individuals who fail to have an adequate period of sleep (7-8 hours in 24 hours) or who have been awake longer than the conventional 16-17 hours will suffer sleep deprivation. (wikipedia.org)
  • temporary
  • Temporary fatigue is likely to be a minor illness like the common cold as one part of the sickness behavior response that happens when the immune system fights an infection. (wikipedia.org)
  • Auditory fatigue is defined as a temporary loss of hearing after exposure to sound. (wikipedia.org)
  • Usually, minor bending of the stereocilia of the inner ear is associated with temporary hearing loss and is involved in auditory fatigue. (wikipedia.org)
  • Temporary threshold shifts related to auditory fatigue are related to the amplitude of a stimulus-driven traveling wave. (wikipedia.org)
  • exertion
  • The fatigue is not due to strenuous ongoing exertion, is not much relieved by rest, and is not due to a previous medical condition. (wikipedia.org)
  • Fatigue is a normal response to physical exertion or stress, but can also be a sign of a physical disorder. (wikipedia.org)
  • accidents
  • It has been estimated that 4-7% of civil aviation incidents and accidents can be attributed to fatigued pilots. (wikipedia.org)
  • In the last 16 years, fatigue has been associated with 250 fatalities in air carrier accidents. (wikipedia.org)
  • Fatigue is a major safety concern in many fields, but especially in transportation, because fatigue can result in disastrous accidents. (wikipedia.org)
  • periods
  • Regulators attempt to mitigate fatigue by limiting the amount of hours pilots are allowed to fly over varying periods of time. (wikipedia.org)
  • Those with a conventional sleep pattern (sleeping for seven or eight hours at night) experience periods of maximum fatigue in the early hours of the morning and a lesser period in the early afternoon. (wikipedia.org)
  • A sleep deficit accumulates with successive sleep-deprived days, and additional fatigue may be caused by breaking daily sleep into two shorter periods in place of a single unbroken period of sleep. (wikipedia.org)
  • common
  • Here are some common strategies for managing fatigue. (bccancer.bc.ca)
  • Macroscopic and microscopic discontinuities (at the crystalline grain scale) as well as component design features which cause stress concentrations (holes, keyways, sharp changes of load direction etc.) are common locations at which the fatigue process begins. (wikipedia.org)
  • disastrous
  • George Loewenstein has suggested that the disastrous failure of men in high office to control impulses in their private lives may at times be attributed to decision fatigue stemming from the burden of day-to-day decision making. (wikipedia.org)
  • cause
  • Less directly, cancer may cause fatigue when it creates toxic substances that disrupt cell functions. (nccn.org)
  • This is the first accident in history for which pilot fatigue was cited as the primary cause. (wikipedia.org)
  • Because each presynaptic cell can link up to thousands of connections with other neurons, synaptic fatigue and its recovery can cause interactions with other neuronal circuits and can affect the kinetics with other processes of neurons. (wikipedia.org)
  • neuromuscular
  • Physical fatigue can be caused by a lack of energy in the muscle, by a decrease of the efficiency of the neuromuscular junction or by a reduction of the drive originating from the central nervous system. (wikipedia.org)
  • affects
  • One United States Air Forces study found significant discrepancies regarding how fatigue affects different individuals. (wikipedia.org)
  • Stanford University Professor of Psychology Carol Dweck found "that while decision fatigue does occur, it primarily affects those who believe that willpower runs out quickly. (wikipedia.org)
  • Fatigue is considered an internal precondition for unsafe acts because it negatively affects the human operator's internal state. (wikipedia.org)
  • Industrial or "time-on-task" fatigue describes fatigue that is accumulated during the working period, and affects performance at different times during the shift. (wikipedia.org)
  • different
  • To the exerciser, the word 'fatigue' denotes many different concepts, such as not completing a set or being too exhausted to run a few more steps on a long distance run. (unm.edu)
  • Fatigue is different from drowsiness, where a patient feels that sleep is required. (wikipedia.org)
  • Anosmia is the permanent loss of the sense of smell, and is different from olfactory fatigue. (wikipedia.org)
  • Synaptic fatigue can affect many synapses of many different types of neurons. (wikipedia.org)