• amyloidosis
  • Myalgia (rare in isolation) Erysipeloid (a skin reaction on the legs, rare in isolation) Fever without any of the other symptoms listed above (25%) AA-amyloidosis with kidney failure is a complication and may develop without overt crises. (wikipedia.org)
  • Among people with familial Mediterranean fever, this particular mutation is also associated with an increased risk of developing amyloidosis, a complication in which abnormal protein deposits can lead to kidney failure. (wikipedia.org)
  • Clinical
  • Although an occasional similar case was found in previous published series, including some in which such manifestations were interpreted as "Henoch" purpura (from which Siegal clearly differentiated the condition), this landmark article was essentially the first to describe the clinical presentation of what is now known as familial Mediterranean fever. (annals.org)
  • disease
  • the disease clearly has Mediterranean roots and FMF seems to attack Spaniards, Greeks, Japanese, Northern Europeans, Italians and Ashkenzi Jews (www.genome.gov). (bartleby.com)
  • Yellow fever is a deadly disease caused by a viral infection that is transmitted through the bite of an infected mosquito. (bartleby.com)
  • Acute rheumatic fever (ARF) is defined by Mosby (2010) as a systemic inflammatory disease which is enabled development with inadequate treatment of upper respiratory tract infections of group A beta-hemolytic streptococci. (bartleby.com)
  • The disease is more prevalent among populations surrounding the Mediterranean Sea and the Middle East. (renalandurologynews.com)
  • Fever is a hallmark of disease and may be present on vital signs. (clinicaladvisor.com)
  • This disease is very common in populations of the Mediterranean area, and due to its high carrier frequency and occurrence rate in these populations, it has been the focus of much research work. (biomedsearch.com)
  • Familial Mediterranean fever (FMF) is a disease of early onset which can lead to significant morbidity. (bmj.com)
  • affects people
  • The condition usually affects people of Mediterranean ancestry, especially non-Ashkenazi (Sephardic) Jews, Armenians, and Arabs, although people from other ethnic groups may also be affected. (northside.com)