• cardiac
  • If left uncorrected, patency leads to pulmonary hypertension and possibly congestive heart failure and cardiac arrhythmias. (wikipedia.org)
  • development
  • If failure to thrive is prolonged, the effects may be long lasting, and normal growth and development may not be achieved. (health.am)
  • The ductus arteriosus is formed from the left 6th aortic arch during embryonic development and attaches to the final part of the aortic arch (the isthmus of aorta) and the first part of the pulmonary artery Failure of the DA to close after birth results in a condition called patent ductus arteriosus and the generation of a left-to-right shunt. (wikipedia.org)