• cells
  • These results suggest that, consistent with a GTP-dependent regulation of Rab function, GDP-bound Rab11b indirectly inhibits Ca 2+ -triggered exocytosis by causing the loss of hGH from the PC12 cells, whereas GTP-bound Rab11b directly impairs Ca 2+ -triggered exocytosis. (jneurosci.org)
  • In this study, we examine the mechanism by which the voltage-dependent K + (Kv) channel Kv2.1 ( KCNB1 ) facilitates depolarization-induced exocytosis in INS 832/13 cells and β-cells from human donors with and without type 2 diabetes (T2D). (diabetesjournals.org)
  • Exocytosis is "infiltration of the epidermis by inflammatory or circulating blood cells. (wikipedia.org)
  • Cellular
  • Especially, regulating exocytosis of the nanoparticles is a key factor in the fabrication of effective nanocarriers for chemotherapeutic treatments but orthogonal control of exocytosis in the cellular environment is a major challenge. (rsc.org)
  • form
  • However, a truncated channel (Kv2.1-ΔC318) that retains electrical function and syntaxin 1A binding, but lacks the ability to form clusters, does not enhance granule recruitment or exocytosis. (diabetesjournals.org)
  • model
  • Herein, we present the first example of regulating exocytosis of gold nanoparticles (AuNPs), a model drug carrier, by using a simple host-guest supramolecular system. (rsc.org)