• patients
  • The effects of carbon monoxide on exercise tolerance as assessed by the distance walked in 12 minutes were studied in 15 patients with severe chronic bronchitis and emphysema (mean forced expiratory volume in one second 0.56 1, mean forced vital capacity 1.54 1). (bmj.com)
  • There was a significant reduction in the walking distance when the patients breathed air after exposure to carbon monoxide (p less than 0.01), and the significant increase in walking distance seen after exercise when breathing oxygen at 2 1/minute via nasal cannulae was abolished if carbon monoxide has previously been administered. (bmj.com)
  • Thus concentrations of carboxyhaemoglobin frequently found in bronchitic patients who smoke may reduce their tolerance of everyday exercise, possibly by interfering with the transport of oxygen to exercising muscles. (bmj.com)
  • Among the benefits expected to result from a therapeutic intervention in patients with impaired systemic functioning is an increase in exercise tolerance. (ersjournals.com)
  • This proposal will focus on (1) estimating oxidative capacity of specific muscle groups during exercise using near infrared spectroscopy and (2) describing body composition to better understand exercise capacity and mitochondrial function in ambulatory spinal muscular atrophy (SMA) patients and disease controls. (clinicaltrials.gov)
  • The results from this study would provide preliminary data, using non-invasive methods, on oxidative capacity in ambulatory SMA patients and disease controls to aid in the design of exercise intervention studies. (clinicaltrials.gov)
  • Patients with chronic heart failure (CHF) and/or chronic obstructive pulmonary disease (COPD) often have reduced exercise tolerance, limiting participation in daily activities. (hindawi.com)
  • Advanced heart failure (HF) patients may stay for a long period of time in the hospital for the treatment of HF and prolonged inactivity causes complications that result in worsening of exercise tolerance. (ahajournals.org)
  • This study investigated the effects of FES on neurovascular control and exercise tolerance in HF hospitalized patients. (ahajournals.org)
  • Is pulmonary vascular resistance index predictive of exercise tolerance in adult patients with idiopathic pulmonary arterial hypertension. (biomedsearch.com)
  • The primary objective is to comparatively evaluate the isolated effects of a long-acting beta2-adrenergic (formoterol fumarate 12µg b.i.d. via Aeroliser) and combined with a long-acting anti-cholinergic (tiotropium bromide 18µg o.d via Handihaler) on breathlessness, dynamic hyperinflation and exercise tolerance in patients with advanced, but stable, chronic obstructive pulmonary disease. (clinicaltrials.gov)
  • Patients are assigned to one of the following three groups (1) endurance training consisted of 20 min exercise sessions on a calibrated ergocycle two times a week, with a target training intensity at 60% of individual maximum oxygen uptake, (2) systemic weightlifting training two times a week with eight different exercises, each session consist of 15 repetitions of each muscle group, (3) combination of endurance training and systemic weightlifting training. (clinicaltrials.gov)
  • Intervention
  • Without knowledge of these features, any absolute or per cent increase in tolerance time to a single constant-load exercise bout must be interpreted with caution regarding the physiological benefit(s) that have accrued from the intervention. (ersjournals.com)
  • These recommendations were based on the demonstrations that the improvement in the maximum work rate attained on the ramp-type incremental exercise test, in response to a particular intervention, was relatively small and often close to the limit of the "minimum clinically important difference" 3 . (ersjournals.com)
  • In contrast, the change in time to the limit of tolerance ( t LIM ) on a constant-load test, chosen to be a high fraction of the maximum incremental work rate, was shown to be appreciably larger and hence considered to be more discriminatory, to the extent that investigators now often forego the post-intervention maximum incremental test 4 - 6 . (ersjournals.com)
  • physiological
  • Exercise tolerance or physiological fitness appears to be important in quantifying the relation between alcohol intake and blood pressure and should be considered in describing this relation. (ahajournals.org)
  • Physical exercise is important for maintaining physical fitness and can contribute to maintaining a healthy weight, regulating digestive health, building and maintaining healthy bone density, muscle strength, and joint mobility, promoting physiological well-being, reducing surgical risks, and strengthening the immune system. (wikipedia.org)
  • maximal
  • 2. The effects of 2 weeks on two levels of salt intake (50 and 150 mmol/day) on the ability to exercise (60% of maximal oxygen uptake) in a hot environment (35°C) were studied in eight healthy normotensive subjects. (clinsci.org)
  • Each evaluation include a stepwise exercise test on an ergocycle up to the individual maximal capacity during which minute ventilation (VE), oxygen consumption (VO2), carbon dioxide production (VCO2), and arterial lactic acid concentration will be measured and the peripheral muscle strength will be determined with the one repetition maximum for eight different muscle groups. (clinicaltrials.gov)
  • clinical
  • In the American Thoracic Society/American College of Chest Physicians statement on cardiopulmonary exercise testing, the authors recognised that "although the incremental protocol is most widely used in clinical practice, constant work rate protocols are gaining popularity because of their clinical applicability, particularly for monitoring response(s) to therapy" 1 . (ersjournals.com)
  • BACKGROUND: Clinical trials for adults with pulmonary arterial hypertension use exercise capacity, as measured by walking distance, as the primary endpoint to measure symptomatic improvement. (biomedsearch.com)
  • abnormalities
  • The objective of the proposed study is to more accurately define the lung and exercise abnormalities in a group of 20 boys from 8-18 years of age with Fabry disease who have not been treated with enzyme replacement therapy (Fabrazyme). (clinicaltrials.gov)
  • adult
  • Childhood obesity is a growing global concern, and physical exercise may help decrease some of the effects of childhood and adult obesity. (wikipedia.org)
  • In the United States, a 1995 CDC/ACSM consensus statement and a Surgeon General's 1996 report state that every adult should participate in moderate exercise, such as walking, swimming, and household tasks, for a minimum of 30 minutes daily. (wikipedia.org)
  • functional
  • Anaerobic exercise also include weight training, functional training, eccentric training, Interval training, sprinting, and high-intensity interval training increase short-term muscle strength. (wikipedia.org)
  • In the U.S. human space program, the only in-flight countermeasure to skeletal muscle functional deficits that has been utilized thus far is physical exercise. (wikipedia.org)
  • capacity
  • Thus, normal exercise capacity as determined by pVO(2) is related to the indexed stroke volume in males and left atrial pressure in females. (diva-portal.org)
  • Whether or not lung function and exercise capacity is abnormal in children is unknown. (clinicaltrials.gov)
  • RESULTS: There is a weak correlation between changes in PVRI and exercise capacity. (biomedsearch.com)
  • Efforts should be made to try to understand the current status of in-flight and post-flight exercise performance capacity and what the goals/target areas for protection are with the current in flight exercise program. (wikipedia.org)
  • dietary
  • 1. Salt restriction is recommended in the treatment of hypertension and is included in national dietary guidelines, but its effect on exercise in hot conditions has not been extensively studied. (clinsci.org)
  • Prospective countermeasures may include pharmacologic and/or dietary interventions, innovative exercise hardware providing improved loading modalities, locomotor training devices, passive exercise devices, and artificial gravity either as an integral component of the spacecraft or as a discrete device contained within it. (wikipedia.org)
  • muscle
  • However, the relationships between in-flight exercise, muscle changes and performance are not well understood. (wikipedia.org)
  • Collective knowledge gained from these mission has aided in the evolution of exercise hardware and protocols in attempts to refine the approach to prevention of spaceflight-induced muscle atrophy and the concomitant deficits in skeletal muscle function. (wikipedia.org)
  • intake
  • Plasma renin activity and aldosterone concentration were elevated after 2 weeks on the reduced salt intake and remained so during exercise. (clinsci.org)
  • 5. The estimated sweat rate during exercise was similar on the two salt intakes but the loss of sodium was less on the low salt intake. (clinsci.org)
  • Plasma
  • 4. Plasma sodium, potassium and osmolality were similar on the two salt intakes both before and during exercise. (clinsci.org)
  • moderate
  • 6. On the basis of these results it is concluded that moderate salt restriction does not impair the ability to exercise in a hot environment. (clinsci.org)
  • People who participate in moderate to high levels of physical exercise have a lower mortality rate compared to individuals who by comparison are not physically active. (wikipedia.org)
  • Moderate levels of exercise have been correlated with preventing aging by reducing inflammatory potential. (wikipedia.org)
  • oxygen
  • No differences in mean oxygen uptake, heart rate or rectal temperature during exercise were observed between the two salt intakes. (clinsci.org)
  • physical
  • Physical exercise is any bodily activity that enhances or maintains physical fitness and overall health and wellness. (wikipedia.org)
  • Frequent and regular physical exercise boosts the immune system[citation needed] and helps prevent certain "diseases of affluence" such as coronary heart disease, type 2 diabetes, and obesity[citation needed]. (wikipedia.org)
  • minutes
  • The majority of the benefits from exercise are achieved with around 3500 metabolic equivalent (MET) minutes per week. (wikipedia.org)
  • normal
  • This is due to the lack of normal pH fall during exercise, which impairs the creatine kinase equilibrium and exaggerates the rise of ADP. (wikipedia.org)