• AMPA
  • α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptor antagonists are of potential interest for the treatment of certain acute and chronic neurodegenerative diseases, including amyotrophic lateral sclerosis. (aspetjournals.org)
  • occur
  • Graded potentials that occur at approximately the same time on a membrane are summed. (brainscape.com)
  • Backpropagating action potentials cannot occur because after an action potential travels down a given segment of the axon, the voltage gated sodium channels' (Na+ channels) m gate becomes closed, thus blocking any transient opening of the h gate from causing a change in the intracellular [Na+], and preventing the generation of an action potential back towards the cell body. (wikipedia.org)
  • Scaling has been found to occur when the strength of all of a neuron's excitatory inputs are scaled up or down. (wikipedia.org)
  • AMPAR
  • This is because they lack surface AMPAR to pass current at hyperpolarized potentials, but do possess NMDARs that will pass current at more positive potentials (because of relief of magnesium block). (wikipedia.org)
  • stimuli
  • For example, repetitive presentation of sound stimuli can lead to a long-lasting increase in the auditory-evoked potential in human and mouse cortex as assessed, respectively, with surface electrodes and transcranial fluorescence imaging ( 20 , 21 ). (pnas.org)
  • occurs
  • We have recently discovered a phenomenon that may be related to intestinal hypersensitivity and hyper-reflexia, sustained slow postsynaptic excitation (SSPE), which occurs in intrinsic sensory neurones of the small intestine. (bmj.com)
  • response
  • The Bienenstock, Cooper and Munro model (BCM model) proposes that a certain threshold exists such that a level of postsynaptic response below the threshold leads to LTD and above it leads to LTP. (wikipedia.org)