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  • TRANSLATIONAL
  • Over twelve factors are involved in PEPTIDE CHAIN INITIATION, TRANSLATIONAL in eukaryotic cells. (curehunter.com)
  • 21536732 ). In tissues responsive to insulin, controls fatty acid synthesis and glycolysis by exerting translational control of adipogenic transcription factors such as CEBPB, CEBPD and ATF4 that have G/C rich or uORF in their 5'UTR. (uniprot.org)
  • Molecular
  • Inhibition of eukaryotic translation initiation by the marine natural product pateamine A". Molecular Cell. (wikipedia.org)
  • Although the basic molecular mechanisms are conserved across the three domains of life, the Bacteria (eubacteria), Archaea (archaebacteria), and Eukarya (eukaryotes), important divergences have taken place as eukaryotic species have evolved. (hindawi.com)
  • Plasmodium
  • Thus, to complete their life cycle, Plasmodium sporozoites exploit the mechanism that regulates stress responses in eukaryotic cells. (gla.ac.uk)
  • COP9
  • Its primary sequence contains a PCI (Proteasome, COP9, Initiation factor 3) domain, a spectrin domain, and a 10-amino acid repeat domain (Pincheira et al. (atlasgeneticsoncology.org)
  • COP9 constitutive photomorphogenic homolog subunit 5 has been shown to interact with Macrophage migration inhibitory factor, GFER, BCL3, Ubiquitin carboxy-terminal hydrolase L1, S100A7 and C-jun. (wikipedia.org)
  • complex
  • Consequently translation comes to a halt since initiation is no longer possible without any available ternary complex. (acris-antibodies.com)
  • The activity of this complex is regulated by rapamycin, insulin, growth factors, phosphatidic acid, certain amino acids and their derivatives (e.g. (wikipedia.org)
  • Mitogens, such as insulin like growth factor 1 (IGF1), can activate the MAPK/ERK pathway, which can inhibit the TSC1/TSC2 complex, activating mTORC1. (wikipedia.org)
  • genomes
  • Epigenomic maintenance is a continuous process and plays an important role in stability of eukaryotic genomes by taking part in crucial biological mechanisms like DNA repair. (wikipedia.org)
  • occurs
  • DNA damage, due to environmental factors and normal metabolic processes inside the cell, occurs at a rate of 10,000 to 1,000,000 molecular lesions per cell per day. (wikipedia.org)
  • sequences
  • Within metazoa (animal kingdom), the core binding factor (CBF)-DNA complex retains a high degree of conservation within the CCAAT binding motif, as well as the sequences flanking this pentameric motif. (wikipedia.org)
  • In an experiment done with core binding factors (CBF) and DNA complexes, researchers were able to determine the preferential sequences of the promoter in a region over and immediately adjacent to the CAAT box, and two regions on either side of the CAAT box. (wikipedia.org)
  • However, the initiation sequences are generally either AT-rich or exhibit bent or curved DNA topology. (wikipedia.org)
  • Distinct
  • Although the various stages of interphase are not usually morphologically distinguishable, each phase of the cell cycle has a distinct set of specialized biochemical processes that prepare the cell for initiation of cell divisions. (wikipedia.org)
  • cells
  • Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. (uniprot.org)
  • May act as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. (uniprot.org)
  • In human cells, both normal metabolic activities and environmental factors such as radiation can cause DNA damage, resulting in as many as 1 million individual molecular lesions per cell per day. (wikipedia.org)
  • cellular
  • The download elementary differential tracking issued in this detection matched the single images of the cellular failure maximum factor bottom( STEP1) genome as it provides to post articles where online entries feel human. (mydigishots.com)
  • growth
  • Somatoliberin precursor (Growth hormone-releasing factor) (GRF) (Growth hormone-releasing hormone) (GHRH) (Somatocrinin) (Somatorelin) (Sermorelin). (yellowcouch.org)
  • begin
  • Although tau monomer has been considered to be natively unstructured, our findings belie this assumption and suggest that initiation of pathological aggregation could begin with conversion of tau monomer from an inert to a seed-competent form. (elifesciences.org)
  • rate
  • The rate of DNA repair is dependent on many factors, including the cell type, the age of the cell, and the extracellular environment. (wikipedia.org)
  • cell type
  • These factors vary by cell type and gestational age and can be affected by changes to the in utero environment and maternal immunity. (jci.org)