• dose
  • The usual starting dose for adults is 4 nanograms of epoprostenol for each kilogram of body weight, for each minute it is given. (drugs.com)
  • After 2 years (epoprostenol dose 32 ng/kg/min) she was in class II with a good effort tolerance (6MWD 490 m), and a second invasive evaluation documented an improvement of hemodynamics (mPAP 26 mmHg, CI 2.9 l/min/m2, PVR 4.7 WU). (medcraveonline.com)
  • found
  • Zwissler also found that inhaled epoprostenol produced the same reduction in pulmonary vascular resistance and increase in PaO2 at 10ng/kg/min as it did at 25ng/kg/min. (everydayebm.org)
  • No evidence of platelet dysfunction or an increase in surgical bleeding after administration of inhaled epoprostenol has been found. (wikipedia.org)
  • blood
  • It can be used during kidney dialysis (to stop your blood from clotting), or it can be used to treat primary and secondary pulmonary hypertension - where Epoprostenol Gebro widens the blood vessels in the lungs and so lowers the blood pressure in your lungs. (drugs.com)
  • During dialysis, Epoprostenol Gebro will be slowly injected into the blood going into the dialysis machine. (drugs.com)
  • further
  • Stability of epoprostenol XX, either diluted for immediate use and tested at 25°C, 30°C and 40°C for up to 72 h, or following storage for up to 8 days at 5°C after reconstitution and immediate dilution with further exposure at 25°C and 30°C for up to 48 h, was assessed at 3,000, 15,000 and 60,000 ng/mL. (ersjournals.com)
  • The relative potency of reconstituted and immediately diluted epoprostenol XX after storage for 8 days at 5°C was ≥98% and remained ≥90% after further storage for 24-48h at 25°C or 30°C, depending on concentration. (ersjournals.com)