• sequence
  • The precursor protein goes through the following processing steps before becoming active: ER signal sequence cleavage propeptide cleavage modification of heme cofactor covalent linkage of heme cofactor. (wikipedia.org)
  • amino
  • The human CysLTR1 gene maps to the X chromosome at position Xq13-Xq21, contains three exons with the entire open reading frame located in exon 3, and codes for a protein composed of 337 amino acids. (wikipedia.org)
  • major
  • The major function of eosinophil peroxidase is to catalyze the formation of hypohalous acids from hydrogen peroxide and halide ions in solution. (wikipedia.org)
  • cell
  • The protein has been directly implicated in epithelial cell damage, exfoliation and bronchospasm in allergic diseases. (imperialinnovations.co.uk)
  • CysLTR1 is a G protein-coupled receptor that links to and when bound to its CysLT ligands activates the Gq alpha subunit and/or Ga subunit of its coupled G protein, depending on the cell type. (wikipedia.org)