• endothelial
  • These approaches range from the use of natural membranes, biological polymers and biosynthetic material compositions, to completely synthetic materials as matrices for corneal endothelial cell sheet generation. (mdpi.com)
  • This review gives an overview about currently used materials for the generation of transplantable corneal endothelial cell sheets with a special focus on thermo-responsive polymer coatings. (mdpi.com)
  • Human corneal endothelial cells (HCECs) do not replicate after wounding. (mdpi.com)
  • Therefore, corneal endothelial deficiency can result in irreversible corneal edema. (mdpi.com)
  • Descemet stripping automated endothelial keratoplasty (DSAEK) allows selective replacement of the diseased corneal endothelium. (mdpi.com)
  • These findings indicate that cultured adult HCECs, transplanted with DSAEK surgery, maintain corneal transparency after transplantation and suggest the feasibility of performing DSAEK with HCECs to treat endothelial dysfunction. (mdpi.com)
  • Corneal endothelial cells (CECs) are firmly attached to the underlying Descemet's membrane. (mdpi.com)
  • Corneal endothelial cells are believed to be of neural crest origin [ 1 , 2 ] and form a monolayer of hexagonal cells. (mdpi.com)
  • Due to technical difficulties, treatment for corneal endothelial decompensation, such as pseudophakic or aphakic bullous keratopathy and Fuchs dystrophy, has been limited to penetrating keratoplasty (PKP). (mdpi.com)